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Trial · NCT03827018

Results by group20

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Time to Flare by Week 26MavrilimumabNA95% Confidence Interval NA to NAweeks
Time to Flare by Week 26Placebo25.195% Confidence Interval 16.0 to NAweeks
Sustained Remission Rate at Week 26Mavrilimumab83.295% Confidence Interval 67.9 to 91.6percentage of participants
Sustained Remission Rate at Week 26Placebo49.995% Confidence Interval 29.6 to 67.3percentage of participants
Time to Elevated Erythrocyte Sedimentation Rate (ESR) by Week 26Mavrilimumab26.195% Confidence Interval 16.1 to NAweeks
Time to Elevated Erythrocyte Sedimentation Rate (ESR) by Week 26Placebo12.195% Confidence Interval 8.1 to 16.6weeks
Time to Elevated C-Reactive Protein (CRP) by Week 26MavrilimumabNA95% Confidence Interval 8.1 to NAweeks
Time to Elevated C-Reactive Protein (CRP) by Week 26Placebo12.395% Confidence Interval 3.3 to 24.1weeks
Time to Signs/Symptoms of Giant Cell Arteritis (GCA) or New or Worsening Vasculitis on Imaging by Week 26MavrilimumabNA95% Confidence Interval NA to NAweeks
Time to Signs/Symptoms of Giant Cell Arteritis (GCA) or New or Worsening Vasculitis on Imaging by Week 26Placebo25.195% Confidence Interval 15.1 to NAweeks
Cumulative Corticosteroid Dose at Week 26Mavrilimumab2074.15Standard Deviation 708.433mg
Cumulative Corticosteroid Dose at Week 26Placebo2402.98Standard Deviation 1014.446mg
Percentage of Participants Who Completed the 26-Week Corticosteroid Taper and Who Had a Normal ESRMavrilimumab45.295% Confidence Interval 29.8 to 61.3percentage of participants
Percentage of Participants Who Completed the 26-Week Corticosteroid Taper and Who Had a Normal ESRPlacebo14.395% Confidence Interval 4.0 to 32.7percentage of participants
Percentage of Participants Who Completed the 26-Week Corticosteroid Taper and Who Had a Normal CRP LevelMavrilimumab23.895% Confidence Interval 12.1 to 39.5percentage of participants
Percentage of Participants Who Completed the 26-Week Corticosteroid Taper and Who Had a Normal CRP LevelPlacebo14.395% Confidence Interval 4.0 to 32.7percentage of participants
Percentage of Participants Who Completed the 26-week Corticosteroid Taper and Who Had No Signs or Symptoms of GCA Nor New or Worsening Vasculitis by Imaging by Week 26Mavrilimumab71.495% Confidence Interval 55.4 to 84.3percentage of participants
Percentage of Participants Who Completed the 26-week Corticosteroid Taper and Who Had No Signs or Symptoms of GCA Nor New or Worsening Vasculitis by Imaging by Week 26Placebo32.195% Confidence Interval 15.9 to 52.4percentage of participants
Cumulative Corticosteroid Dose at the End of the Washout Safety Follow-up PeriodMavrilimumab2464.93Standard Deviation 1106.636mg
Cumulative Corticosteroid Dose at the End of the Washout Safety Follow-up PeriodPlacebo2845.45Standard Deviation 1320.115mg

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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