Trial · NCT03864523
Effect of Pioglitazone Administered to Patients With Adrenomyeloneuropathy
NCT03864523, Phase 2, Completed, Pujol, Aurora, M.D.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Pioglitazone Administered to Patients With Adrenomyeloneuropathy. Trials, record NCT03864523. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03864523
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Pioglitazone Administered to Patients With Adrenomyeloneuropathy
- NCT number
- NCT03864523
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 18 participants, actual
- Lead sponsor
- Pujol, Aurora, M.D.
- Conditions
- Adrenomyeloneuropathy, X-linked Adrenoleukodystrophy
- Interventions
- Pioglitazone
- First posted
- 2019-03-06
- Last updated
- 2019-09-10
Source ClinicalTrials.gov
Registered outcomes56
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 2 Minute Walk Test (2MWT) | 24 months | The score at this test corresponds to the distance traveled by the patient during 2 minutes, on a flat surface |
| Secondary | Timed Up and Go (TUG) test | 24 months | It consists in standing up, walking 3 meters, turning around, walk back to the chair and sitting back down, at regular pace |
| Secondary | Time to walk 25 Feet (TW25) | 24 months | In this test the patient should walk 7.62 meters (25 feet) as quickly, but safely, as possible without running |
| Secondary | 6 Minute Walk Test (6MWT) | 24 months | It measures the distance an individual is able to walk over a total of six minutes on a hard, flat surface |
| Secondary | Sensory disturbances: tactile | 24 months | For the evaluation the Total Neuropathy Score (TNS) will be used (0-4) |
| Secondary | Sensory disturbances: painful | 24 months | For the evaluation the Total Neuropathy Score (TNS) will be used (0-4) |
| Secondary | Sensory disturbances: vibratory | 24 months | For the evaluation the Total Neuropathy Score (TNS) will be used (0-4) |
| Secondary | Expanded disability status scale (EDSS) | 24 months | This scale measures motor function, ranging from 0 (normal neurological examination) to 10 (death) |
| Secondary | Dynamometer test (optional) | 24 months | It measures the muscle strength |
| Secondary | Ashworth scale | 24 months | The Modified Ashworth Scale measures spasticity in patients who have lesions of the CNS or neurological disorders. The modified Ashworth scale ranges from 0 (no increase in tone) to 4 (Affected part(s) rigid in flexion or extension) |
1 to 10 of 56Source ClinicalTrials.gov
See all 56 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03864523
GET https://conductscience.org/api/trials/v1/NCT03864523/registered?page=2