Trial · NCT04383262
Registered outcomes24
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 20 of 24
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Reflux Symptom Index (RSI) | Baseline to 12-week post-treatment. | The absolute change from baseline (i.e., Pretreatment) in symptom severity as indicated by RSI Score over time, with the primary treatment comparison at Week 12 (End of Treatment Visit) |
| Primary | Change in Daily Symptom Reflux Diary (DRSD) | Baseline to 12-week post-treatment. | The absolute change from baseline (i.e., Pretreatment) in symptom severity as indicated by Weekly Total DRSD Score (WTDS) over time, with the primary treatment comparison at Week 12 (End of Treatment Visit) |
| Other | Change in Reflux Finding (RFS) | Baseline to 12-week post-treatment. | The absolute change from baseline in endoscopic signs severity as indicated by Reflux Finding Score (RFS) over time, with the primary treatment comparison at Week 12 |
| Other | Change in Reflux Symptom Scale (RSS). | Baseline to 12-week post-treatment. | The absolute change from baseline in symptom severity as indicated by Reflux Symptom Score (RSS) over time, with the primary treatment comparison at Week 12 |
| Other | Change in Reflux Sign Assessment (RSA) | Baseline to 12-week post-treatment. | The absolute change from baseline in endoscopic signs severity as indicated by Reflux Sign Assessment (RSA) score over time, with the primary treatment comparison at Week 12 |
| Other | Change in Voice Handicap Index 10 (VHI-10) | Baseline to 12-week post-treatment. | The absolute change from baseline in symptom severity as indicated by Voice Handicap Index-10 (VHI-10) score over time, with the primary treatment comparison at Week 12 |
| Other | Change in symptom-free days | Baseline to week 12 | The absolute change from baseline in weekly overall reflux symptom-free days as indicated by Weekly Symptom-Free Days (WSFD; i.e. the total number of symptom-free days per week, with symptom-free defined as "Did not have" response for all items on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "throat-clearing" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "throat-clearing" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "throat-clearing" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "sensation of something stuck in the throat" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "sensation of something stuck in the throat" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "sensation of something stuck in the throat" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "excess mucus in the throat" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "excess mucus in the throat" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "excess mucus in the throat" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "throat pain" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "throat pain" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "throat pain" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "problem with the sound of your voice" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "problem with the sound of your voice" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "problem with the sound of your voice" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "difficulty swallowing" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "difficulty swallowing" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "difficulty swallowing" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "heartburn" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "heartburn" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "heartburn (sensation of burning feeling behind the breastbone)" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "regurgitation" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "regurgitation" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "regurgitation (liquid or food moving upwards towards your throat or mouth)" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "abdominal pain" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "abdominal pain" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "abdominal pain" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "bad breath" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "bad breath" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "bad breath" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "cough" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "cough" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "cough" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in "difficulty breathing" | Baseline to 12-week post-treatment | The absolute change from baseline in weekly "difficulty breathing" symptom-free days (i.e. the total number of days per week that the patient responded "Did not have" for "difficulty breathing" item on the DRSD), over time, with the primary exploratory treatment comparison at Week 12 |
| Other | Change in Reflux Symptom Index (RSI) up to week 4 | Baseline to week 4 post-treatment. | The absolute change from baseline in symptom severity as indicated by RSI score over time, (up to Week 4), with the primary treatment comparison at Week 4 |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT04383262/registered