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Trial · NCT04396366

Results by group208

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline In Bacterial Load Colony-forming Units of Potentially Pathogenic Microorganisms in Sputum at Week 12QBW251 300 mg b.i.d-0.192Standard Deviation 1.4621CFU/mL
Change From Baseline In Bacterial Load Colony-forming Units of Potentially Pathogenic Microorganisms in Sputum at Week 12Placebo0.340Standard Deviation 1.6476CFU/mL
Number of Participants With Absence of Any Colony-forming Units of Potentially Pathogenic Bacteria SputumQBW251 300 mg b.i.d0Participants
Number of Participants With Absence of Any Colony-forming Units of Potentially Pathogenic Bacteria SputumPlacebo0Participants
Change From Baseline in Quality of Life Questionnaire for Bronchiectasis (QOL-B) (Respiratory Symptoms Domain)QBW251 300 mg b.i.dDay 28 n=12,195.247Standard Deviation 10.9936score on a scale
Change From Baseline in Quality of Life Questionnaire for Bronchiectasis (QOL-B) (Respiratory Symptoms Domain)PlaceboDay 28 n=12,197.212Standard Deviation 9.5209score on a scale
Change From Baseline in Quality of Life Questionnaire for Bronchiectasis (QOL-B) (Respiratory Symptoms Domain)QBW251 300 mg b.i.dDay 56 n=12,201.852Standard Deviation 5.8026score on a scale
Change From Baseline in Quality of Life Questionnaire for Bronchiectasis (QOL-B) (Respiratory Symptoms Domain)PlaceboDay 56 n=12,201.852Standard Deviation 11.7429score on a scale
Change From Baseline in Quality of Life Questionnaire for Bronchiectasis (QOL-B) (Respiratory Symptoms Domain)QBW251 300 mg b.i.dDay 84 n=13,202.849Standard Deviation 9.4612score on a scale
Change From Baseline in Quality of Life Questionnaire for Bronchiectasis (QOL-B) (Respiratory Symptoms Domain)PlaceboDay 84 n=13,203.519Standard Deviation 11.9848score on a scale
Change From Baseline in Fibrinogen Plasma ConcentrationQBW251 300 mg b.i.d-0.193Standard Deviation 0.6278g/L
Change From Baseline in Fibrinogen Plasma ConcentrationPlacebo-0.127Standard Deviation 0.4828g/L
Change From Baseline in Daily Rescue Medication Use (Salbutamol/Albuterol)QBW251 300 mg b.i.d-0.37Standard Deviation 1.069number of puffs
Change From Baseline in Daily Rescue Medication Use (Salbutamol/Albuterol)Placebo0.14Standard Deviation 0.895number of puffs
Change From Baseline in Pre-bronchodilator Forced Exploratory Volume in the First Second (FEV1)QBW251 300 mg b.i.dDay 28 n=20,20-0.002Standard Deviation 0.1113liters
Change From Baseline in Pre-bronchodilator Forced Exploratory Volume in the First Second (FEV1)PlaceboDay 28 n=20,200.012Standard Deviation 0.1541liters
Change From Baseline in Pre-bronchodilator Forced Exploratory Volume in the First Second (FEV1)QBW251 300 mg b.i.dDay 56 n=18,180.031Standard Deviation 0.1086liters
Change From Baseline in Pre-bronchodilator Forced Exploratory Volume in the First Second (FEV1)PlaceboDay 56 n=18,180.007Standard Deviation 0.1137liters
Change From Baseline in Pre-bronchodilator Forced Exploratory Volume in the First Second (FEV1)QBW251 300 mg b.i.dDay 84 n=17,190.045Standard Deviation 0.1650liters
Change From Baseline in Pre-bronchodilator Forced Exploratory Volume in the First Second (FEV1)PlaceboDay 84 n=17,190.022Standard Deviation 0.1260liters

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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