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Trial · NCT04442503

Results by group78

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline (CFB) in the 17-item Hamilton Rating Scale for Depression (HAM-D) Total Score at Day 15PlaceboBaseline28.8Standard Deviation 2.34score on a scale
Change From Baseline (CFB) in the 17-item Hamilton Rating Scale for Depression (HAM-D) Total Score at Day 15SAGE-217 50 mgBaseline28.6Standard Deviation 2.49score on a scale
Change From Baseline (CFB) in the 17-item Hamilton Rating Scale for Depression (HAM-D) Total Score at Day 15PlaceboChange from Baseline at Day 15-11.4Standard Deviation 8.50score on a scale
Change From Baseline (CFB) in the 17-item Hamilton Rating Scale for Depression (HAM-D) Total Score at Day 15SAGE-217 50 mgChange from Baseline at Day 15-15.6Standard Deviation 7.62score on a scale
Change From Baseline in the 17-item HAM-D Total ScorePlaceboBaseline28.8Standard Deviation 2.34score on a scale
Change From Baseline in the 17-item HAM-D Total ScoreSAGE-217 50 mgBaseline28.6Standard Deviation 2.49score on a scale
Change From Baseline in the 17-item HAM-D Total ScorePlaceboChange from Baseline at Day 3-6.3Standard Deviation 6.78score on a scale
Change From Baseline in the 17-item HAM-D Total ScoreSAGE-217 50 mgChange from Baseline at Day 3-9.5Standard Deviation 7.40score on a scale
Change From Baseline in the 17-item HAM-D Total ScorePlaceboChange from Baseline at Day 28-13.5Standard Deviation 8.77score on a scale
Change From Baseline in the 17-item HAM-D Total ScoreSAGE-217 50 mgChange from Baseline at Day 28-16.3Standard Deviation 8.34score on a scale
Change From Baseline in the 17-item HAM-D Total ScorePlaceboChange from Baseline at Day 45-14.8Standard Deviation 9.09score on a scale
Change From Baseline in the 17-item HAM-D Total ScoreSAGE-217 50 mgChange from Baseline at Day 45-17.7Standard Deviation 8.40score on a scale
Change From Baseline in Clinical Global Impressions - Severity Scale (CGI-S) ScorePlaceboBaseline4.9Standard Deviation 0.58score on a scale
Change From Baseline in Clinical Global Impressions - Severity Scale (CGI-S) ScoreSAGE-217 50 mgBaseline5.0Standard Deviation 0.66score on a scale
Change From Baseline in Clinical Global Impressions - Severity Scale (CGI-S) ScorePlaceboChange from Baseline at Day 15-1.6Standard Deviation 1.38score on a scale
Change From Baseline in Clinical Global Impressions - Severity Scale (CGI-S) ScoreSAGE-217 50 mgChange from Baseline at Day 15-2.2Standard Deviation 1.51score on a scale
Percentage of Participants With HAM-D ResponsePlaceboDay 1538.9percentage of participants
Percentage of Participants With HAM-D ResponseSAGE-217 50 mgDay 1557.0percentage of participants
Percentage of Participants With HAM-D ResponsePlaceboDay 4554.1percentage of participants
Percentage of Participants With HAM-D ResponseSAGE-217 50 mgDay 4561.9percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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