Trial · NCT04591678
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 11 of 11
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Muscle strength | 22 months | To evaluate the effect of nusinersen treatment on muscle strength in ambulatory SMA adults |
| Secondary | Change in Six Minute Walk Test | 22 months | 6 Minute Walk Test (6WMT) |
| Secondary | Change in Hammersmith Functional Motor Scale Expanded | 22 months | Hammersmith Functional Motor Scale Expanded (HFMSE) |
| Secondary | Change in SMA Functional Rating Scale | 22 months | modified SMA Functional Rating Scale(SMA-FRS) |
| Secondary | Change in Forced Vital Capacity | 22 months | Forced Vital Capacity (FVC) |
| Secondary | Change in Negative Inspiratory Force | 22 months | Negative Inspiratory Force (NIF) |
| Secondary | Change in lean muscle mass | 22 months | Muscle mass measured using Dual-Energy X-Ray Absorptiometry (DXA) |
| Secondary | Change in Quality of Life | 22 months | Quality of life will be measured using 36-Item Short Form Survey (SF-36) |
| Secondary | Change in Ulnar and Peroneal muscle measures | 22 months | Compound Muscle Action Potential Amplitude (CMAP) will be recorded |
| Secondary | Change in Motor Unit Number Estimation (MUNE) | 22 months | Ulnar nerve (Recording at the Abductor Digiti Minimi muscle) MUNE scores will be recorded |
| Secondary | Number of participants that experience Adverse Events (AEs) and Serious Adverse Events (SAEs) | 22 months | Number of participants who experience adverse outcomes |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT04591678/registered