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Trial · NCT04658654

Registered outcomes15

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryVerbal Learning Test (VLT) (15 words)Change from baseline to 24 weeks of chronic intake
SecondaryAlzheimer's disease Assessment Scale- Cognitive Sub-scale (ADAS-Cog scale)Change from baseline to 24 weeks of chronic intake
SecondaryMini Mental State Examination (MMSE)Change from baseline to 24 weeks of chronic intake
SecondaryPattern Separation TaskChange from baseline to 24 weeks of chronic intake
SecondaryTrail-Making Test (TMT)Change from baseline to 24 weeks of chronic intake
SecondaryLetter Digit Substitution Test (LDST)Change from baseline to 24 weeks of chronic intake
SecondaryHospital Anxiety and Depression Scale (HADS)Change from baseline to 24 weeks of chronic intake
SecondaryAlzheimer's disease co-operative study activities of daily living (ADCS-ADL) scaleChange from baseline to 24 weeks of chronic intake
SecondaryNeuropsychiatric Inventory (NPI)Change from baseline to 24 weeks of chronic intake
SecondaryQoL-ADChange from baseline to 24 weeks of chronic intake
SecondaryEuroQolChange from baseline to 24 weeks of chronic intake
SecondaryBoston Naming TaskChange from baseline to 24 weeks of chronic intake
OtherConversion to Alzheimer's disease (AD)24 weeks
OtherPharmacokinetic validation of roflumilast and its active metabolite roflumilast N-Oxide in plasmaAcute, 12 weeks chronic intake and 24 weeks chronic intake
OtherTau in tearsChange from baseline to 24 weeks of chronic intake

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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