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Trial · NCT04667104

Results by group211

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants With a Reduction of at Least 2 log10 International Unit/Millilitres (IU/mL) in Hepatitis B Surface Antigen (HBsAg) Levels From Baseline to Week 24TP 2:JNJ-3989 200 mg+JNJ-6379 250 mg+PegIFN-alpha2a 180 mcg+NA64.690% Confidence Interval 51.73percentage of participants
Percentage of Participants With Treatment Emergent Adverse Events (TEAEs) as a Measure of Safety and TolerabilityTP 1:JNJ-73763989 200 mg+JNJ-56136379 250 mg+NA52.1percentage of participants
Percentage of Participants With Treatment Emergent Adverse Events (TEAEs) as a Measure of Safety and TolerabilityTP 2:JNJ-3989 200 mg+JNJ-6379 250 mg+PegIFN-alpha2a 180 mcg+NA87.5percentage of participants
Percentage of Participants With Treatment Emergent Adverse Events (TEAEs) as a Measure of Safety and TolerabilityFollow-Up (FU) Period-nucleos(t)Ide Analog (NA)60.4percentage of participants
Percentage of Participants With Serious Adverse Events (SAEs) as a Measure of Safety and TolerabilityTP 1:JNJ-73763989 200 mg+JNJ-56136379 250 mg+NA0percentage of participants
Percentage of Participants With Serious Adverse Events (SAEs) as a Measure of Safety and TolerabilityTP 2:JNJ-3989 200 mg+JNJ-6379 250 mg+PegIFN-alpha2a 180 mcg+NA2.1percentage of participants
Percentage of Participants With Serious Adverse Events (SAEs) as a Measure of Safety and TolerabilityFollow-Up (FU) Period-nucleos(t)Ide Analog (NA)8.3percentage of participants
Number of Participants With Clinically Significant Abnormalities in Vital Signs as a Measure of Safety and TolerabilityTP 1:JNJ-73763989 200 mg+JNJ-56136379 250 mg+NA0Participants
Number of Participants With Clinically Significant Abnormalities in Vital Signs as a Measure of Safety and TolerabilityTP 2:JNJ-3989 200 mg+JNJ-6379 250 mg+PegIFN-alpha2a 180 mcg+NA0Participants
Number of Participants With Clinically Significant Abnormalities in Vital Signs as a Measure of Safety and TolerabilityFollow-Up (FU) Period-nucleos(t)Ide Analog (NA)0Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityTP 1:JNJ-73763989 200 mg+JNJ-56136379 250 mg+NATreatment-emergent (TE)-Grade 3 ALT elevations1Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityTP 2:JNJ-3989 200 mg+JNJ-6379 250 mg+PegIFN-alpha2a 180 mcg+NATreatment-emergent (TE)-Grade 3 ALT elevations1Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityFollow-Up (FU) Period-nucleos(t)Ide Analog (NA)Treatment-emergent (TE)-Grade 3 ALT elevations1Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityTP 1:JNJ-73763989 200 mg+JNJ-56136379 250 mg+NATE-Grade 3 total bilirubin elevations0Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityTP 2:JNJ-3989 200 mg+JNJ-6379 250 mg+PegIFN-alpha2a 180 mcg+NATE-Grade 3 total bilirubin elevations0Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityFollow-Up (FU) Period-nucleos(t)Ide Analog (NA)TE-Grade 3 total bilirubin elevations1Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityTP 1:JNJ-73763989 200 mg+JNJ-56136379 250 mg+NATE-Grade 3 direct bilirubin elevations0Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityTP 2:JNJ-3989 200 mg+JNJ-6379 250 mg+PegIFN-alpha2a 180 mcg+NATE-Grade 3 direct bilirubin elevations0Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityFollow-Up (FU) Period-nucleos(t)Ide Analog (NA)TE-Grade 3 direct bilirubin elevations2Participants
Number of Participants With Clinically Significant Abnormalities in Laboratory Findings as a Measure of Safety and TolerabilityTP 1:JNJ-73763989 200 mg+JNJ-56136379 250 mg+NATreatment-emergent-High serum indirect bilirubin0Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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