Trial · NCT05103228
Cumulative Pregnancy Rate With Lower and Higher Gonadotropin Dose During IVF Among Poor Responders
NCT05103228, Not applicable, Completed, Peter Kovacs MD; results first posted 2024-12-13
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cumulative Pregnancy Rate With Lower and Higher Gonadotropin Dose During IVF Among Poor Responders. Trials, record NCT05103228. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05103228
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cumulative Pregnancy Rate With Lower and Higher Gonadotropin Dose During IVF Among Poor Responders
- NCT number
- NCT05103228
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 190 participants, actual
- Lead sponsor
- Peter Kovacs MD
- Conditions
- Infertility, Ovarian Dysfunction
- Interventions
- Follitropin Alfa, Follitropin delta, human menopausal gonadotropin
- First posted
- 2021-11-02
- Last updated
- 2024-12-13
- Results first posted
- 2024-12-13
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Cumulative Clinical Pregnancy Rate | 18 months | an ultrasound confirmation of an intrauterine gestational sac with an embryo with detectable heartbeat in it after the fresh + if available frozen embryo transfer treatments |
| Secondary | Live Birth Rate | 12 months | delivery of a viable newborn after 24 weeks gestation |
| Secondary | Cumulative Live Birth Rate | 12 months | Cumulative live birth: delivery of a viable newborn after 24 weeks gestation after the fresh embryo transfer or if it is unsuccessful but surplus embryos were frozen then after any of the subsequent frozen embryo transfer cycles. All these transfers (fresh and frozen) are the result of a single stimulation. If a live birth is reached during the fresh or any of the subsequent frozen transfers from the same stimulation then it is considered a positive outcome; if the fresh transfer or any of the subsequent frozen transfers from the same stimulation do not result in a live birth it is considered a negative result. |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Cumulative Clinical Pregnancy Rate | 18 months | intention to treat | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Live Birth Rate | 12 months | Intentition to treat population | live births | NUMBER |
| SECONDARY | Cumulative Live Birth Rate | 12 months | live births | NUMBER |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Cumulative Clinical Pregnancy Rate | Lower Gonadotropin Dose Stimulation | 27 | Participants | ||
| Cumulative Clinical Pregnancy Rate | Higher Gonadotropin Dose Stimulation | 17 | Participants | ||
| Live Birth Rate | Lower Gonadotropin Dose Stimulation | 15 | live births | ||
| Live Birth Rate | Higher Gonadotropin Dose Stimulation | 10 | live births | ||
| Cumulative Live Birth Rate | Lower Gonadotropin Dose Stimulation | 17 | live births | ||
| Cumulative Live Birth Rate | Higher Gonadotropin Dose Stimulation | 13 | live births |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Lower Gonadotropin Dose Stimulation | 98 | |
| Overall Study | STARTED | Higher Gonadotropin Dose Stimulation | 92 | |
| Overall Study | COMPLETED | Lower Gonadotropin Dose Stimulation | 94 | |
| Overall Study | COMPLETED | Higher Gonadotropin Dose Stimulation | 91 | |
| Overall Study | NOT COMPLETED | Lower Gonadotropin Dose Stimulation | 4 | |
| Overall Study | NOT COMPLETED | Higher Gonadotropin Dose Stimulation | 1 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Lower Gonadotropin Dose Stimulation | 0 | 94 |
| Total, all-cause mortality | Higher Gonadotropin Dose Stimulation | 1 | 91 |
| Total, other adverse events | Lower Gonadotropin Dose Stimulation | 0 | 94 |
| Total, other adverse events | Higher Gonadotropin Dose Stimulation | 0 | 91 |
| Total, serious adverse events | Lower Gonadotropin Dose Stimulation | 0 | 94 |
| Total, serious adverse events | Higher Gonadotropin Dose Stimulation | 0 | 91 |
Source ClinicalTrials.gov
Papers20
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons3
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Lower Gonadotropin Dose Stimulation vs Higher Gonadotropin Dose Stimulation: Cumulative Clinical Pregnancy Rate | Trial comparisons |
| Lower Gonadotropin Dose Stimulation vs Higher Gonadotropin Dose Stimulation: deaths from any cause | Trial comparisons |
| Lower Gonadotropin Dose Stimulation vs Higher Gonadotropin Dose Stimulation: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05103228
GET https://conductscience.org/api/trials/v1/NCT05103228/registered