Trial · NCT05284110
Breaking up Sedentary Time in Rheumatoid Arthritis
NCT05284110, Not applicable, Unknown, Liverpool John Moores University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Breaking up Sedentary Time in Rheumatoid Arthritis. Trials, record NCT05284110. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05284110
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Breaking up Sedentary Time in Rheumatoid Arthritis
- NCT number
- NCT05284110
- Status
- Unknown
- Phases
- Not applicable
- Enrollment
- 12 participants, estimated
- Lead sponsor
- Liverpool John Moores University
- Conditions
- Rheumatoid Arthritis, Sedentary Behavior, Endothelial Dysfunction
- Interventions
- Physical activity
- First posted
- 2022-03-17
- Last updated
- 2023-10-04
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Middle cerebral artery mean velocity (MCAV) | Change from baseline (hour 0) to hour 4 (post-intervention/control) | MCAV will be assessed using continuous bilateral transcranial Doppler ultrasound. |
| Primary | Middle cerebral artery mean velocity reactivity to carbon dioxide | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Participants will breathe a 5% carbon dioxide mixture for 3 min during which time MCAV reactivity to CO2 will be assessed using continuous bilateral transcranial Doppler ultrasound. |
| Primary | Cerebral autoregulation | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Participants will be asked to complete a series of repeated sit to stand moves (coached by a member of the research team) for a 5-minute period, during which time MCAV will be assessed using continuous bilateral transcranial Doppler ultrasound. Beat by beat blood pressure will also be assessed using finger photoplethysmography. |
| Secondary | Brachial artery endothelial function | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Brachial artery endothelial function will be assessed through flow-mediated dilation using vascular ultrasound. |
| Secondary | Finger blood pressure | Change from baseline (hour 0) to hour 4 (post-intervention/control) | During all procedures, beat by beat finger blood pressure will be measured on the middle finger of the right hand using photoplethysmography. |
| Secondary | Superficial femoral artery endothelial function | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Superficial femoral artery endothelial function will be assessed through flow-mediated dilation using vascular ultrasound. |
| Secondary | Skin blood flow response to hyperemia | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Skin blood flow response to hyperemia will be assessed using a laser doppler probe attached to the shin and forearm. |
| Secondary | Stroop color-word test | Change from baseline (hour 0) to hour 4 (post-intervention/control) | The Stroop color-word test will be implemented to assess attention and inhibitory control. |
| Secondary | California Verbal Learning Test-2 | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Immediate recall of the California Verbal Learning Test-2 will be used to assess verbal learning and memory. |
| Secondary | Brachial artery blood flow | Change from baseline to 1-hour/2-hour/3-hour/4-hour | Vascular ultrasound will be used to assess brachial artery blood flow every hour during the intervention |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Verbal Learning | Secondary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05284110
GET https://conductscience.org/api/trials/v1/NCT05284110/registered