Trial · NCT05284110
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 12 of 12
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Middle cerebral artery mean velocity (MCAV) | Change from baseline (hour 0) to hour 4 (post-intervention/control) | MCAV will be assessed using continuous bilateral transcranial Doppler ultrasound. |
| Primary | Middle cerebral artery mean velocity reactivity to carbon dioxide | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Participants will breathe a 5% carbon dioxide mixture for 3 min during which time MCAV reactivity to CO2 will be assessed using continuous bilateral transcranial Doppler ultrasound. |
| Primary | Cerebral autoregulation | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Participants will be asked to complete a series of repeated sit to stand moves (coached by a member of the research team) for a 5-minute period, during which time MCAV will be assessed using continuous bilateral transcranial Doppler ultrasound. Beat by beat blood pressure will also be assessed using finger photoplethysmography. |
| Secondary | Brachial artery endothelial function | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Brachial artery endothelial function will be assessed through flow-mediated dilation using vascular ultrasound. |
| Secondary | Finger blood pressure | Change from baseline (hour 0) to hour 4 (post-intervention/control) | During all procedures, beat by beat finger blood pressure will be measured on the middle finger of the right hand using photoplethysmography. |
| Secondary | Superficial femoral artery endothelial function | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Superficial femoral artery endothelial function will be assessed through flow-mediated dilation using vascular ultrasound. |
| Secondary | Skin blood flow response to hyperemia | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Skin blood flow response to hyperemia will be assessed using a laser doppler probe attached to the shin and forearm. |
| Secondary | Stroop color-word test | Change from baseline (hour 0) to hour 4 (post-intervention/control) | The Stroop color-word test will be implemented to assess attention and inhibitory control. |
| Secondary | California Verbal Learning Test-2 | Change from baseline (hour 0) to hour 4 (post-intervention/control) | Immediate recall of the California Verbal Learning Test-2 will be used to assess verbal learning and memory. |
| Secondary | Brachial artery blood flow | Change from baseline to 1-hour/2-hour/3-hour/4-hour | Vascular ultrasound will be used to assess brachial artery blood flow every hour during the intervention |
| Secondary | Femoral artery blood flow | Change from baseline to 1-hour/2-hour/3-hour/4-hour | Vascular ultrasound will be used to assess femoral artery blood flow every hour during the intervention |
| Secondary | Pain intensity | Change from baseline to 1-hour/2-hour/3-hour/4-hour | Pain intensity will be assessed using a 10cm visual analogue scale. |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT05284110/registered