Trial · NCT06706414
NT-NOA - Novel Treatment of Some Men With Non-Obstructive Azoospermia
NCT06706414, Phase 1, Phase 2, Completed, Martin Blomberg Jensen
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. NT-NOA - Novel Treatment of Some Men With Non-Obstructive Azoospermia. Trials, record NCT06706414. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06706414
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- NT-NOA - Novel Treatment of Some Men With Non-Obstructive Azoospermia
- NCT number
- NCT06706414
- Status
- Completed
- Phases
- Phase 1, Phase 2
- Enrollment
- 16 participants, actual
- Lead sponsor
- Martin Blomberg Jensen
- Conditions
- Infertility, Male
- Interventions
- Denosumab (Prolia), Letrozole (Aromatase Inhibitors)
- First posted
- 2024-11-26
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Sperm in the semen sample or TESE on day 90 | Day 80 (semen sample) and 90 (TESE) after inclusion | Finding of sperm in the semen sample (day 80) or TESE (day 90), that subsequently will be compared with prior TESE if available. |
| Secondary | The change in expression of proliferation (KI-67, PCNA) and apoptosis (cPARP, TUNEL assay) markers in TESE tissue at day 90 compared to prior TESE if available | Day 90 after inclusion | TESE |
| Secondary | The number of participants with sperm in the ejaculate (sperm pr. milliliter) assessed by semen samples delivered on day 14 | Day 14 after inclusion | Semen sample |
| Secondary | The number of participants with sperm in the ejaculate (sperm pr. milliliter) assessed by semen samples delivered on day 80 | Day 80 after inclusion | Semen sample |
| Secondary | The number of pregnancies achieved by sperm from the ejaculate or by TESE | Day 180 after inclusion | Survey |
| Secondary | The change in serum levels of reproductive hormones (FSH, LH, AMH, Inhibin B og INSL3) on day 14 | Day 14 after inclusion | Serum sample |
| Secondary | The change in serum levels of reproductive hormones (FSH, LH, AMH, Inhibin B og INSL3) on day 80 | Day 80 after inclusion | Serum sample |
| Secondary | The change in serum levels of sex steroids (Testosterone, Estradiol and SHBG) on day 14 | Day 14 after inclusion | Serum sample |
| Secondary | The change in serum levels of sex steroids (Testosterone, Estradiol and SHBG) on day 80 | Day 80 after inclusion | Serum sample |
| Secondary | The change in seminal fluid levels of reproductive hormones (AMH, Inhibin B, INSL3) on day 14 | Day 14 after inclusion | Seminal fluid |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers22
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06706414
GET https://conductscience.org/api/trials/v1/NCT06706414/papers?page=2