Registered outcomes19

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

1 to 19 of 19

List	Outcome	Time frame	Description
Primary	Sperm in the semen sample or TESE on day 90	Day 80 (semen sample) and 90 (TESE) after inclusion	Finding of sperm in the semen sample (day 80) or TESE (day 90), that subsequently will be compared with prior TESE if available.
Secondary	The change in expression of proliferation (KI-67, PCNA) and apoptosis (cPARP, TUNEL assay) markers in TESE tissue at day 90 compared to prior TESE if available	Day 90 after inclusion	TESE
Secondary	The number of participants with sperm in the ejaculate (sperm pr. milliliter) assessed by semen samples delivered on day 14	Day 14 after inclusion	Semen sample
Secondary	The number of participants with sperm in the ejaculate (sperm pr. milliliter) assessed by semen samples delivered on day 80	Day 80 after inclusion	Semen sample
Secondary	The number of pregnancies achieved by sperm from the ejaculate or by TESE	Day 180 after inclusion	Survey
Secondary	The change in serum levels of reproductive hormones (FSH, LH, AMH, Inhibin B og INSL3) on day 14	Day 14 after inclusion	Serum sample
Secondary	The change in serum levels of reproductive hormones (FSH, LH, AMH, Inhibin B og INSL3) on day 80	Day 80 after inclusion	Serum sample
Secondary	The change in serum levels of sex steroids (Testosterone, Estradiol and SHBG) on day 14	Day 14 after inclusion	Serum sample
Secondary	The change in serum levels of sex steroids (Testosterone, Estradiol and SHBG) on day 80	Day 80 after inclusion	Serum sample
Secondary	The change in seminal fluid levels of reproductive hormones (AMH, Inhibin B, INSL3) on day 14	Day 14 after inclusion	Seminal fluid
Secondary	The change in seminal fluid levels of reproductive hormones (AMH, Inhibin B, INSL3) on day 80	Day 80 after inclusion	Seminal fluid
Secondary	The change in the endocrine gonadal function (Inhibin B/FSH ratio, Testosterone/LH ratio and AMH/testosterone ratio) on day 14	Day 14 after inclusion	Serum sample
Secondary	The change in the endocrine gonadal function (Inhibin B/FSH ratio, Testosterone/LH ratio and AMH/testosterone ratio) on day 80	Day 80 after inclusion	Serum sample
Other	The change in seminal fluid levels of RANKL, OPG, AMH and Inhibin B on day 14	Day 14 after inclusion	Seminal fluid
Other	The change in seminal fluid levels of RANKL, OPG, AMH and Inhibin B on day 80	Day 80 after inclusion	Seminal fluid
Other	The change in serum levels of minerals (calcium, phosphate, magnesium, zink, bikarbonate, citrate) on day 14	Day 14 after inclusion	Serum
Other	The change in serum levels of minerals (calcium, phosphate, magnesium, zink, bikarbonate, citrate) on day 80	Day 80 after inclusion	Serum
Other	The change in seminal fluid levels of minerals (calcium, phosphate, magnesium, zink, bikarbonate, citrate) on day 14	Day 14 after inclusion	Seminal fluid
Other	The change in seminal fluid levels of minerals (calcium, phosphate, magnesium, zink, bikarbonate, citrate) on day 80	Day 80 after inclusion	Seminal fluid

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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