Trial · NCT07889050
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 12 of 12
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Postoperative pain assessed by Visual Analog Scale (VAS) | 24 hours after root canal treatment | Postoperative pain will be self-assessed by participants using a 100 mm Visual Analog Scale (VAS), consisting of a horizontal line where participants mark the point that best represents their level of pain intensity. The left end (0 mm) indicates "no pain" and the right end (100 mm) indicates "the most severe pain I have ever felt in my life." Scores are measured in millimeters, with higher scores indicating greater pain intensity. Participants will record their VAS score in a standardized pain diary at each assessment time point, along with any rescue analgesic (paracetamol 500 mg) use, including time and dose, and any adverse events or unexpected occurrences. A blinded researcher, unaware of group allocation, will telephone participants at each designated time point to record pain scores and remind them to complete the diary. |
| Secondary | Postoperative pain assessed by Visual Analog Scale (VAS) at 6 Hours | 6 hours after root canal treatment | Postoperative pain will be self-assessed using a 100 mm Visual Analog Scale (VAS). The left end (0 mm) indicates "no pain" and the right end (100 mm) indicates "the most severe pain I have ever felt in my life." Higher scores indicate greater pain intensity. |
| Secondary | Postoperative pain assessed by Visual Analog Scale (VAS) at 12 Hours | 12 hours after root canal treatment | Postoperative pain will be self-assessed using a 100 mm Visual Analog Scale (VAS). The left end (0 mm) indicates "no pain" and the right end (100 mm) indicates "the most severe pain I have ever felt in my life." Higher scores indicate greater pain intensity. |
| Secondary | Postoperative pain assessed by Visual Analog Scale (VAS) at 48 Hours | 48 hours after root canal treatment | Postoperative pain will be self-assessed using a 100 mm Visual Analog Scale (VAS). The left end (0 mm) indicates "no pain" and the right end (100 mm) indicates "the most severe pain I have ever felt in my life." Higher scores indicate greater pain intensity. |
| Secondary | Postoperative pain assessed by Visual Analog Scale (VAS) at 72 Hours | 72 hours after root canal treatment | Postoperative pain will be self-assessed using a 100 mm Visual Analog Scale (VAS). The left end (0 mm) indicates "no pain" and the right end (100 mm) indicates "the most severe pain I have ever felt in my life." Higher scores indicate greater pain intensity. |
| Secondary | Postoperative pain assessed by Visual Analog Scale (VAS) at 7 Days | 7 days (168 hours) after root canal treatment | Postoperative pain will be self-assessed using a 100 mm Visual Analog Scale (VAS). The left end (0 mm) indicates "no pain" and the right end (100 mm) indicates "the most severe pain I have ever felt in my life." Higher scores indicate greater pain intensity. |
| Secondary | Pain Catastrophizing as Assessed by Pain Catastrophizing Scale (PCS) | Baseline, prior to root canal treatment | Pain catastrophizing will be assessed using the Pain Catastrophizing Scale (PCS), a validated self-report questionnaire measuring the tendency to exaggerate the threat value of pain. Higher scores indicate greater pain catastrophizing. |
| Secondary | Dental anxiety assessed by Modified Dental Anxiety Scale (MDAS) | Baseline, prior to root canal treatment | Dental anxiety will be assessed using the Modified Dental Anxiety Scale (MDAS), a validated self-report questionnaire measuring anxiety related to dental treatment. Higher scores indicate greater dental anxiety. |
| Secondary | Salivary irisin level at baseline | Baseline, prior to root canal treatment | Salivary irisin concentration will be measured in unstimulated saliva samples collected using the passive drooling method, analyzed by enzyme-linked immunosorbent assay (ELISA). |
| Secondary | Salivary irisin level at 24 Hours | 24 hours after root canal treatment | Salivary irisin concentration will be measured in unstimulated saliva samples collected using the passive drooling method, analyzed by enzyme-linked immunosorbent assay (ELISA). |
| Secondary | Salivary irisin level at 72 Hours | 72 hours after root canal treatment | Salivary irisin concentration will be measured in unstimulated saliva samples collected using the passive drooling method, analyzed by enzyme-linked immunosorbent assay (ELISA). |
| Secondary | Salivary irisin level in healthy reference group | At the time of saliva sample collection, single time point | Salivary irisin concentration will be measured in a single unstimulated saliva sample collected from healthy participants without an indication for root canal treatment, using the passive drooling method and analyzed by enzyme-linked immunosorbent assay (ELISA), to establish normative reference values. |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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