Trial · NCT07894393
Haemodynamic Effects of Four Sevoflurane Wash-In Strategies After Tracheal Intubation
NCT07894393, Not applicable, Completed, Ataturk University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Haemodynamic Effects of Four Sevoflurane Wash-In Strategies After Tracheal Intubation. Trials, record NCT07894393. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07894393
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Haemodynamic Effects of Four Sevoflurane Wash-In Strategies After Tracheal Intubation
- NCT number
- NCT07894393
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 102 participants, actual
- Lead sponsor
- Ataturk University
- Conditions
- Anesthesia, General, Hypotension
- Interventions
- End-tidal-controlled sevoflurane wash-in, Low-flow high-concentration wash-in (0.5 L/min, 8% sevoflurane), Low-flow wash-in (1 L/min, 4% sevoflurane), Moderate-flow wash-in (2 L/min, 4% sevoflurane)
- First posted
- 2026-10-26
- Last updated
- 2026-10-26
Source ClinicalTrials.gov
Registered outcomes17
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Cardiac index | 10 minutes after endotracheal intubation | Cardiac index (L/min/m2) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line, compared between the four wash-in groups. |
| Secondary | Systolic arterial pressure | Before induction (T0), 30 seconds after intubation (T1), when 0.8 MAC is reached (T2) and 10 minutes after intubation (T3) | Systolic arterial pressure (mmHg) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. |
| Secondary | Diastolic arterial pressure | Before induction (T0), 30 seconds after intubation (T1), when 0.8 MAC is reached (T2) and 10 minutes after intubation (T3) | Diastolic arterial pressure (mmHg) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. |
| Secondary | Mean arterial pressure | Before induction (T0), 30 seconds after intubation (T1), when 0.8 MAC is reached (T2) and 10 minutes after intubation (T3) | Mean arterial pressure (mmHg) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. |
| Secondary | Heart rate | Before induction (T0), 30 seconds after intubation (T1), when 0.8 MAC is reached (T2) and 10 minutes after intubation (T3) | Heart rate (beats/min) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. |
| Secondary | Cardiac index at other time points | Before induction (T0), 30 seconds after intubation (T1) and when 0.8 MAC is reached (T2) | Cardiac index (L/min/m2) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. |
| Secondary | Stroke volume index | Before induction (T0), 30 seconds after intubation (T1), when 0.8 MAC is reached (T2) and 10 minutes after intubation (T3) | Stroke volume index (mL/m2) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. |
| Secondary | Pulse pressure variation | 30 seconds after intubation (T1), when 0.8 MAC is reached (T2) and 10 minutes after intubation (T3) | Pulse pressure variation (%) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. Not assessed at T0 because patients were breathing spontaneously. |
| Secondary | Cardiac cycle efficiency | Before induction (T0), 30 seconds after intubation (T1), when 0.8 MAC is reached (T2) and 10 minutes after intubation (T3) | Cardiac cycle efficiency (unitless index, range -1 to +1) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. |
| Secondary | Maximum rate of arterial pressure rise (dP/dt) | Before induction (T0), 30 seconds after intubation (T1), when 0.8 MAC is reached (T2) and 10 minutes after intubation (T3) | Maximum rate of rise of the radial arterial pressure, dP/dt (mmHg/ms) measured with the pressure recording analytical method (PRAM; MostCare Up) via a radial arterial line. At each time point, the highest value among five consecutive beats was recorded. |
1 to 10 of 17Source ClinicalTrials.gov
See all 17 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07894393
GET https://conductscience.org/api/trials/v1/NCT07894393/registered