Trial · NCT07908368
Pulse Wave vs. Saline Contrast EIT for Pulmonary Perfusion in ARDS
NCT07908368, Recruiting, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Pulse Wave vs. Saline Contrast EIT for Pulmonary Perfusion in ARDS. Trials, record NCT07908368. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07908368
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pulse Wave vs. Saline Contrast EIT for Pulmonary Perfusion in ARDS
- NCT number
- NCT07908368
- Status
- Recruiting
- Enrollment
- 20 participants, estimated
- Lead sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT), Mechanical Ventilation
- First posted
- 2026-11-02
- Last updated
- 2026-11-02
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pulmonary perfusion was assessed using both pulse wave and saline bolus EIT at PEEP levels of 5 and 15 cmH₂O. | Under both PEEP 5 cmH₂O and PEEP 15 cmH₂O conditions, EIT data were acquired after 30 minutes of stable ventilation. | At a PEEP of 5 cmH₂O, pulse wave EIT data were recorded for 3 minutes. Subsequently, during an inspiratory or expiratory hold, a 10 mL bolus of 10% hypertonic saline was administered via the central venous catheter while EIT data were simultaneously recorded for another 3 minutes. This procedure was repeated at a PEEP of 15 cmH₂O. Pulmonary perfusion data were obtained through offline analysis of the EIT data. |
| Secondary | At PEEP 5 cmH₂O and 15 cmH₂O, perform EIT monitoring of pulmonary perfusion during a 15-second inspiratory or expiratory hold. | Under both PEEP 5 cmH₂O and PEEP 15 cmH₂O conditions, EIT data were acquired after 30 minutes of stable ventilation. | At a PEEP of 5 cmH₂O, EIT data were first recorded for 1 minute, followed by a 15-second inspiratory hold, after which data acquisition was continued for an additional 2 minutes. The entire procedure was repeated at a PEEP of 15 cmH₂O. Pulmonary perfusion data were subsequently analyzed using offline software. |
| Secondary | Under PEEP 5 cmH₂O conditions, EIT data were acquired during bolus injections of either 10 mL of 0.9% saline or 10 mL of 10% hypertonic saline for pulmonary perfusion analysis. | Under a PEEP of 5 cmH₂O, EIT data acquisition was performed after 30 minutes of stable ventilation. | At a PEEP of 5 cmH₂O, the following protocol was performed: First, EIT data were recorded for 1 minute, followed by a bolus injection of 10 mL of 0.9% saline via the central venous catheter; data acquisition then continued for an additional 2 minutes. Then, the procedure was repeated with a bolus injection of 10 mL of 10% hypertonic saline. Pulmonary perfusion data were subsequently analyzed using offline software. |
| Secondary | The ventilation-perfusion matching percentage was assessed using both pulse wave and saline bolus EIT at PEEP levels of 5 and 15 cmH₂O. | Under both PEEP 5 cmH₂O and PEEP 15 cmH₂O conditions, EIT data were acquired after 30 minutes of stable ventilation. | The ventilation-perfusion matching percentage was derived from EIT images using offline analysis software. |
| Secondary | The ventilation-perfusion matching percentage was monitored by EIT during 15-second inspiratory or expiratory holds at PEEP levels of 5 and 15 cmH₂O. | Under both PEEP 5 cmH₂O and PEEP 15 cmH₂O conditions, EIT data were acquired after 30 minutes of stable ventilation. | The ventilation-perfusion matching percentage was derived from EIT images using offline analysis software. |
| Secondary | Under PEEP 5 cmH₂O conditions, EIT data were acquired during bolus injections of either 10 mL of 0.9% saline or 10 mL of 10% hypertonic saline for ventilation-perfusion matching percentage. | Under a PEEP of 5 cmH₂O, EIT data acquisition was performed after 30 minutes of stable ventilation. | The ventilation-perfusion matching percentage was derived from EIT images using offline analysis software. |
| Secondary | The dead space percentage was assessed using both pulse wave and saline bolus EIT at PEEP levels of 5 and 15 cmH₂O. | Under both PEEP 5 cmH₂O and PEEP 15 cmH₂O conditions, EIT data were acquired after 30 minutes of stable ventilation. | The ventilation-perfusion matching percentage was derived from EIT images using offline analysis software. |
| Secondary | The dead space percentage was monitored by EIT during 15-second inspiratory or expiratory holds at PEEP levels of 5 and 15 cmH₂O. | Under both PEEP 5 cmH₂O and PEEP 15 cmH₂O conditions, EIT data were acquired after 30 minutes of stable ventilation. | The ventilation-perfusion matching percentage was derived from EIT images using offline analysis software. |
| Secondary | Under PEEP 5 cmH₂O conditions, the dead space percentage was obtained by EIT monitoring following bolus injections of either 10 mL of 0.9% saline or 10 mL of 10% hypertonic saline. | Under PEEP 5 cmH₂O conditions, EIT data were acquired after 30 minutes of stable ventilation. | The ventilation-perfusion matching percentage was derived from EIT images using offline analysis software. |
| Secondary | The shunt percentage was assessed using both pulse wave and saline bolus EIT at PEEP levels of 5 and 15 cmH₂O. | Under both PEEP 5 cmH₂O and PEEP 15 cmH₂O conditions, EIT data were acquired after 30 minutes of stable ventilation. | The ventilation-perfusion matching percentage was derived from EIT images using offline analysis software. |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07908368
GET https://conductscience.org/api/trials/v1/NCT07908368/registered