Trial · NCT07911176
Timing, Trajectories and Prediction in Severe Dental Crowding: The Create SPACE (cSPACE)
NCT07911176, Not applicable, Not yet recruiting, Vastra Gotaland Region
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Timing, Trajectories and Prediction in Severe Dental Crowding: The Create SPACE (cSPACE). Trials, record NCT07911176. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07911176
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Timing, Trajectories and Prediction in Severe Dental Crowding: The Create SPACE (cSPACE)
- NCT number
- NCT07911176
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 300 participants, estimated
- Lead sponsor
- Vastra Gotaland Region
- Conditions
- Crowding of Teeth, Malocclusion; Displaced Teeth, Malocclusion in Children
- Interventions
- Early first premolar extraction with observation, Early first premolar extraction with planned fixed orthodontic treatment
- First posted
- 2026-11-02
- Last updated
- 2026-11-02
Source ClinicalTrials.gov
Registered outcomes20
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Final Peer Assessment Rating (PAR) | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | The primary analysis will compare the three randomized treatment strategies with respect to the final PAR score at 18 years of age, adjusted for baseline PAR score, according to the prespecified statistical analysis plan. PAR scores will be assessed on digital study models. |
| Secondary | Spontaneous alignment of crowded teeth | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Dental alignment assessed on digital study models using tooth size arch length discrepency (TSALD, mm) and Little's Irregularity Index (LII, mm) |
| Secondary | Spontaneus extraction space closure | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Space closure closure assessed on digital study models using extent of space closure (mm). |
| Secondary | Sagittal skeletal relationship assessed by ANB Angle | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Sagittal skeletal relationship asessed using ANB angle (degrees) on lateral cephalometric radiographs. |
| Secondary | Sagittal skeletal relationship assessed by Wits appraisal | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Sagittal skeletal relationship asessed using Wits appraisal (mm) on lateral cephalometric radiographs. |
| Secondary | Change in jaw inclination (ML/NSL Angle) | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Vertical skeletal relationship asessed using jaw the ML/NSL angle (degrees) on lateral cephalometric radiographs. |
| Secondary | Facial height changes | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Vertical skeletal relationship asessed using facial height (mm) measurements on lateral cephalometric radiographs. |
| Secondary | Nasolabial angle changes | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Soft-tissue relationships assessed using nasolabial angle (degrees) anon lateral cephalometric radiographs and profile photographs. |
| Secondary | Lip positions relative to Rickett's estethic line | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Soft-tissue relationships assessed as the distance from the upper and lower lips to Ricketts' estethic line (mm) on lateral cephalometric radiographs and profile photographs. |
| Secondary | Tooth inclination changes on cephalometric radiographs | Baseline, 14 years of age, 16 years of age, and 18 years of age (through study completion). | Tooth inclination assessed on lateral cephalometric radiographs using anagular measurments (degrees). |
1 to 10 of 20Source ClinicalTrials.gov
See all 20 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07911176
GET https://conductscience.org/api/trials/v1/NCT07911176/registered