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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last2,141 to 2,160 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Part B (Blinded): mRNA-1273 at Month 6 vs Part B (Blinded): mRNA-1273.222 at Month 6: Part B: Number of Participants With a First Occurrence of CDC-based COVID-19 Starting 14 Days After Month 6 Dose Until End of Follow up in RM6 Cohort Between Month 6 Monovalent and Bivalent Boost Groups151 of 1,976

142 of 2,012

0.6 points

-1.0 to 2.2

3,988NCT05168813

Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern

Part B (Blinded): mRNA-1273 at Month 6 vs Part B (Blinded): mRNA-1273.222 at Month 6: Part B: Number of Participants With a First Occurrence of COVE-based Severe COVID-19 Starting 14 Days After Month 6 Dose Until End of Follow up in RM6 Cohort Between Month 6 Monovalent and Bivalent Groups1 of 1,976

0 of 2,012

0.1 points

-0.1 to 0.3

3,988NCT05168813

Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern

Part B (Blinded): mRNA-1273 at Month 6 vs Part B (Blinded): mRNA-1273.222 at Month 6: Part B: Number of Participants With a First Occurrence of COVE-based COVID-19 Starting 14 Days After Month 6 Dose Until End of Follow up in RM6 Cohort Between Month 6 Monovalent and Bivalent Boost Group8 of 1,976

7 of 2,012

0.1 points

-0.4 to 0.5

3,988NCT05168813

Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern

Telcagepant 140 mg vs Placebo: Number of Participants With Clinical Adverse Events (AEs)1,582 of 2,660

804 of 1,326

-1.2 points

-4.4 to 2.1

3,986NCT01125774

Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)

Telcagepant 140 mg vs Placebo: Number of Participants Who Discontinued Study Due to a Clinical AE66 of 2,660

36 of 1,326

-0.2 points

-1.4 to 0.8

3,986NCT01125774

Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)

Telcagepant 140 mg vs Placebo: serious adverse events25 of 2,660

10 of 1,326

0.2 points

-0.5 to 0.7

3,986NCT01125774

Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)

Active Antihypertensive Treatment vs Usual Care: Recurrent Stroke28 of 1,988

43 of 1,987

-0.8 points

-1.6 to 0.1

3,975NCT01840072

China Antihypertensive Trial in Acute Ischemic Stroke

Active Antihypertensive Treatment vs Usual Care: Other Vascular Events48 of 1,988

59 of 1,987

-0.6 points

-1.6 to 0.5

3,975NCT01840072

China Antihypertensive Trial in Acute Ischemic Stroke

Active Antihypertensive Treatment vs Usual Care: Mortality68 of 1,988

54 of 1,987

0.7 points

-0.4 to 1.8

3,975NCT01840072

China Antihypertensive Trial in Acute Ischemic Stroke

Active Antihypertensive Treatment vs Usual Care: A Combination of All-cause Mortality and Major Disability at the 3-month Post-treatment Follow-up.500 of 1,988

502 of 1,987

-0.1 points

-2.8 to 2.6

3,975NCT01840072

China Antihypertensive Trial in Acute Ischemic Stroke

Tiotropium vs Placebo: serious adverse events342 of 1,952

336 of 1,965

0.4 points

-1.9 to 2.8

3,917NCT00387088

Tiotropium / Respimat One Year Study in COPD.

Telcagepant 140 mg vs Placebo: Number of Participants With Laboratory AEs76 of 2,610

30 of 1,305

0.6 points

-0.5 to 1.6

3,915NCT01125774

Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)

Telcagepant 140 mg vs Placebo: Number of Participants Who Discontinued Study Due to a Laboratory AE8 of 2,610

2 of 1,305

0.2 points

-0.3 to 0.5

3,915NCT01125774

Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)

EBQI-Supported WH-PACT Implementation vs Routine WH-PACT Implementation: deaths from any cause5 of 2,720

3 of 1,180

-0.1 points

-0.6 to 0.2

3,900NCT02039856

Implementation of Women's Health Patient Aligned Care Teams

Tiotropium vs Placebo: Number of Patients With at Least One Hospitalisation for a COPD Exacerbation161 of 1,939

198 of 1,953

-1.8 points

-3.7 to -0.0

3,892NCT00387088

Tiotropium / Respimat One Year Study in COPD.

Tiotropium vs Placebo: Number of Patients With at Least One COPD Exacerbation685 of 1,939

842 of 1,953

-7.8 points

-10.8 to -4.7

3,892NCT00387088

Tiotropium / Respimat One Year Study in COPD.

Letrozole vs Placebo: serious adverse events80 of 1,951

87 of 1,938

-0.4 points

-1.7 to 0.9

3,889NCT00382070

Letrozole in Treating Postmenopausal Women Who Have Received Hormone Therapy for Hormone Receptor-Positive Breast Cancer

Group 1: Ad26.Mos4.HIV + Clade C and Mosaic gp140 vs Group 2: Placebo: Number of Participants With Serious Adverse Events (SAEs)82 of 1,942

77 of 1,945

0.3 points

-1.0 to 1.5

3,887NCT03964415

A Study of Heterologous Vaccine Regimen of Adenovirus Serotype 26 Mosaic4 Human Immunodeficiency Virus(Ad26.Mos4.HIV), Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals Who Have Sex With Cis-gender Men and/or Transgender Individuals

Group 1: Ad26.Mos4.HIV + Clade C and Mosaic gp140 vs Group 2: Placebo: Number of Participants With Medically-attended Adverse Events (MAAEs)999 of 1,942

1,002 of 1,945

-0.1 points

-3.2 to 3.1

3,887NCT03964415

A Study of Heterologous Vaccine Regimen of Adenovirus Serotype 26 Mosaic4 Human Immunodeficiency Virus(Ad26.Mos4.HIV), Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals Who Have Sex With Cis-gender Men and/or Transgender Individuals

Group 1: Ad26.Mos4.HIV + Clade C and Mosaic gp140 vs Group 2: Placebo: Number of Participants Who Discontinued the Study or Study Intervention Due to Adverse Events (AEs)11 of 1,942

16 of 1,945

-0.3 points

-0.8 to 0.3

3,887NCT03964415

A Study of Heterologous Vaccine Regimen of Adenovirus Serotype 26 Mosaic4 Human Immunodeficiency Virus(Ad26.Mos4.HIV), Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals Who Have Sex With Cis-gender Men and/or Transgender Individuals

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

No key needed

Code

Show the call in
curl "https://conductscience.org/api/comparisons/v1?page=108"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=108

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT05168813-1bc0a9aa",
        "title": "Part B (Blinded): mRNA-1273 at Month 6 vs Part B (Blinded): mRNA-1273.222 at Month 6: Part B: Number of Participants With a First Occurrence of CDC-based COVID-19 Starting 14 Days After Month 6 Dose Until End of Follow up in RM6 Cohort Between Month 6 Monovalent and Bivalent Boost Groups",
        "summary": "151 of 1976 against 142 of 2012; risk difference 0.6 points, 95% interval -1.0 to 2.2; NCT05168813, Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern",
        "record": "/library/comparisons/NCT05168813-1bc0a9aa",
        "nct_id": "NCT05168813",
        "kind": "outcome",
        "participants": 3988,
        "risk_difference": {
          "value": 0.0058404632931158,
          "lower": -0.010398267347622156,
          "upper": 0.022136695903160374
        },
        "group_1": "151 of 1,976",
        "group_2": "142 of 2,012",
        "difference": "0.6 points",
        "interval": "-1.0 to 2.2",
        "trial_title": "Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern"
      },
      {
        "id": "NCT05168813-774041bd",
        "title": "Part B (Blinded): mRNA-1273 at Month 6 vs Part B (Blinded): mRNA-1273.222 at Month 6: Part B: Number of Participants With a First Occurrence of COVE-based Severe COVID-19 Starting 14 Days After Month 6 Dose Until End of Follow up in RM6 Cohort Between Month 6 Monovalent and Bivalent Groups",
        "summary": "1 of 1976 against 0 of 2012; risk difference 0.1 points, 95% interval -0.1 to 0.3; NCT05168813, Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern",
        "record": "/library/comparisons/NCT05168813-774041bd",
        "nct_id": "NCT05168813",
        "kind": "outcome",
        "participants": 3988,
        "risk_difference": {
          "value": 0.0005060728744939271,
          "lower": -0.001444596914272216,
          "upper": 0.002861128099984624
        },
        "group_1": "1 of 1,976",
        "group_2": "0 of 2,012",
        "difference": "0.1 points",
        "interval": "-0.1 to 0.3",
        "trial_title": "Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=109",
  "request_id": "6a8SuAd_rLqJ7fap"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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