ConductScience.org, home

85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last2,341 to 2,360 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
ERN + Simvastatin vs Placebo + Simvastatin: Composite End Point of CHD Death, Nonfatal MI, Ischemic Stroke, Hospitalization for Non-ST Segment Elevation Acute Coronary Syndrome (ACS), or Symptom-driven Coronary or Cerebral Revascularization282 of 1,718

274 of 1,696

0.3 points

-2.2 to 2.7

3,414NCT00120289

Niacin Plus Statin to Prevent Vascular Events

ERN + Simvastatin vs Placebo + Simvastatin: Cardiovascular Mortality45 of 1,718

38 of 1,696

0.4 points

-0.7 to 1.4

3,414NCT00120289

Niacin Plus Statin to Prevent Vascular Events

ERN + Simvastatin vs Placebo + Simvastatin: Composite Endpoint of CHD Death, Non-fatal MI, High-risk ACS or Ischemic Stroke171 of 1,718

158 of 1,696

0.6 points

-1.3 to 2.6

3,414NCT00120289

Niacin Plus Statin to Prevent Vascular Events

ERN + Simvastatin vs Placebo + Simvastatin: Composite Endpoint of CHD Death, Non-fatal MI, or Ischemic Stroke156 of 1,718

138 of 1,696

0.9 points

-0.9 to 2.8

3,414NCT00120289

Niacin Plus Statin to Prevent Vascular Events

ERN + Simvastatin vs Placebo + Simvastatin: serious adverse events587 of 1,718

551 of 1,696

1.7 points

-1.5 to 4.8

3,414NCT00120289

Niacin Plus Statin to Prevent Vascular Events

M-M-R II ® vs Placebo: serious adverse events11 of 1,722

5 of 1,689

0.3 points

-0.1 to 0.9

3,411NCT04333732

CROWN CORONATION: COVID-19 Research Outcomes Worldwide Network for CORONAvirus prevenTION

Belimumab 10 mg/kg vs Placebo: Number of Participants With All-cause Mortality During Years 2 to 538 of 1,695

58 of 1,670

-1.2 points

-2.4 to -0.1

3,365NCT01705977

Belimumab Assessment of Safety in SLE

Belimumab 10 mg/kg vs Placebo: Number of Participants With New Primary Malignancies During Years 2 to 524 of 1,695

22 of 1,670

0.1 points

-0.7 to 0.9

3,365NCT01705977

Belimumab Assessment of Safety in SLE

Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Fever Above 39.5 Degrees Celsius/103.1 Degrees Fahrenheit18 of 2,527

5 of 831

0.1 points

-0.7 to 0.6

3,358NCT00289783

Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine

QVA149 vs Long Acting B2 Agonist (LABA) and Inhaled Corticosteroid (ICS): serious adverse events308 of 1,678

334 of 1,680

-1.5 points

-4.2 to 1.1

3,358NCT01782326

QVA vs. Salmeterol/Fluticasone, 52-week Exacerbation Study, FLAME (EFfect of Indacaterol Glycopyronium Vs Fluticasone Salmeterol on COPD Exacerbations)

DTaP-IPV vs DAPTACEL®+IPOL®: serious adverse events21 of 2,733

3 of 621

0.3 points

-0.7 to 0.8

3,354NCT01346293

Study of DTap-IPV Compared to DAPTACEL® and IPOL® as the 5th Dose in Children 4 to 6 Years of Age

CKD Enhanced Clinical Decision Support (CKD-CDS Intervention) vs Usual Care: Number of Patients With Optimal Blood Pressure Control334 of 1,633

388 of 1,719

-2.1 points

-4.9 to 0.7

3,352NCT03890588

Chronic Kidney Disease Clinical Decision Support

CKD Enhanced Clinical Decision Support (CKD-CDS Intervention) vs Usual Care: Number of Participants With CKD Diagnosis417 of 1,568

389 of 1,783

4.8 points

1.9 to 7.7

3,351NCT03890588

Chronic Kidney Disease Clinical Decision Support

Rotarix Group vs Placebo Group: Number of Subjects With Any Unsolicited Adverse Events (AEs)310 of 1,666

368 of 1,667

-3.5 points

-6.2 to -0.7

3,333NCT01171963

Study to Assess the Efficacy, Immunogenicity and Safety of Liquid Human Rotavirus Vaccine, in Healthy Chinese Infants

Rotarix Group vs Placebo Group: Number of Subjects With Any Serious Adverse Events (SAEs)183 of 1,666

246 of 1,667

-3.8 points

-6.0 to -1.5

3,333NCT01171963

Study to Assess the Efficacy, Immunogenicity and Safety of Liquid Human Rotavirus Vaccine, in Healthy Chinese Infants

Rotarix Group vs Placebo Group: serious adverse events183 of 1,666

246 of 1,667

-3.8 points

-6.0 to -1.5

3,333NCT01171963

Study to Assess the Efficacy, Immunogenicity and Safety of Liquid Human Rotavirus Vaccine, in Healthy Chinese Infants

Silk-Like Linen vs Standard Cotton Linen: Rate of Development of Unit-acquired Pressure Ulcers45 of 1,626

42 of 1,706

0.3 points

-0.8 to 1.4

3,332NCT02925741

Silk-Like Bed Linens for Prevention of Unit-Acquired Ulcers

Fluarix Group vs Fluzone Group: Number of Subjects Reporting Rare Serious Events11 of 2,115

11 of 1,210

-0.4 points

-1.1 to 0.2

3,325NCT00383123

Study Comparing the Immune Response and Safety of Fluarix and Fluzone Influenza Vaccines in Children

Plain Soap and Water vs Alcohol Based Hand Rubs: Surgical Site Infection128 of 1,682

127 of 1,635

-0.2 points

-2.0 to 1.7

3,317NCT00987402

Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation

Doxorubicin + Cyclophosphamide Followed by Docetaxel (AC -> T) vs Docetaxel + Doxorubicin and Cyclophosphamide (TAC): Local, Regional or Metastatic Relapse, or Second Primary Cancer, or Death From Any Cause (Disease-Free Survival)356 of 1,649

352 of 1,649

0.2 points

-2.6 to 3.0

3,298NCT00312208

Docetaxel in Breast Cancer

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

No key needed

Code

Show the call in
curl "https://conductscience.org/api/comparisons/v1?page=118"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=118

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT00120289-13dc40ff",
        "title": "ERN + Simvastatin vs Placebo + Simvastatin: Composite End Point of CHD Death, Nonfatal MI, Ischemic Stroke, Hospitalization for Non-ST Segment Elevation Acute Coronary Syndrome (ACS), or Symptom-driven Coronary or Cerebral Revascularization",
        "summary": "282 of 1718 against 274 of 1696; risk difference 0.3 points, 95% interval -2.2 to 2.7; NCT00120289, Niacin Plus Statin to Prevent Vascular Events",
        "record": "/library/comparisons/NCT00120289-13dc40ff",
        "nct_id": "NCT00120289",
        "kind": "outcome",
        "participants": 3414,
        "risk_difference": {
          "value": 0.0025877501262986657,
          "lower": -0.022212514811306403,
          "upper": 0.02736597756856697
        },
        "group_1": "282 of 1,718",
        "group_2": "274 of 1,696",
        "difference": "0.3 points",
        "interval": "-2.2 to 2.7",
        "trial_title": "Niacin Plus Statin to Prevent Vascular Events"
      },
      {
        "id": "NCT00120289-5269d466",
        "title": "ERN + Simvastatin vs Placebo + Simvastatin: Cardiovascular Mortality",
        "summary": "45 of 1718 against 38 of 1696; risk difference 0.4 points, 95% interval -0.7 to 1.4; NCT00120289, Niacin Plus Statin to Prevent Vascular Events",
        "record": "/library/comparisons/NCT00120289-5269d466",
        "nct_id": "NCT00120289",
        "kind": "outcome",
        "participants": 3414,
        "risk_difference": {
          "value": 0.003787587585388892,
          "lower": -0.006711562320149066,
          "upper": 0.014356917572183837
        },
        "group_1": "45 of 1,718",
        "group_2": "38 of 1,696",
        "difference": "0.4 points",
        "interval": "-0.7 to 1.4",
        "trial_title": "Niacin Plus Statin to Prevent Vascular Events"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=119",
  "request_id": "-WE94078HFTh_hfX"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
No account. 60 calls a minute from one address.

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

Genes

NCBI Gene

One gene with its proteins, patents, drugs, trials, grants and papers.

Trials

ClinicalTrials.gov

Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.

Sequences

Patent publications

Paste a sequence and see the patents that disclose it.

Opens sequences.conductscience.org

For software

Read Trial comparisons from software.

Every answer on this page is also JSON, under /api/comparisons/v1. No key.

GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome

Ask an assistant

  • In FOURIER, how did serious adverse events compare between evolocumab and placebo?
  • Which metformin trials reported deaths, and what was the risk difference?
  • What was the number needed to treat for HELIOS-B's composite outcome?
  • Which placebo-controlled heart failure trials had the most participants?