ConductScience.org, home

85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last41 to 60 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
PCV13-vaccinated Participants vs Unvaccinated Participants: VE for First Event of ACP at 0-3 Years of Follow-up4,543 of 72,303

27,984 of 320,959

-2.4 points

-2.6 to -2.2

393,262NCT05794191

A Study To Learn About The Effects Of Pneumococcal Vaccine In People With HIV

Aims 1, 2B, and 3 Groups vs Aim 2A Group: deaths from any cause22,208 of 386,276

0 of 25

5.7 points

-7.6 to 5.8

386,301NCT05214573

Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk

Aims 1, 2B, and 3 Groups vs Aim 2A Group: serious adverse events40,642 of 386,276

0 of 25

10.5 points

-2.8 to 10.6

386,301NCT05214573

Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk

Rivaroxaban vs Apixaban: deaths from any cause1,958 of 176,990

1,840 of 176,990

0.1 points

-0.0 to 0.1

353,980NCT05256797

Prediction of the COBRRA AF Anticoagulant Trial in Healthcare Claims Data

Arm 1: Routine Care (Mupirocin/CHG) vs Arm 2: Iodophor/CHG Decolonization: Number of Participants With ICU Attributable MRSA Clinical Cultures1,377 of 168,301

1,682 of 185,022

-0.1 points

-0.2 to -0.0

353,323NCT03140423

Mupirocin-Iodophor ICU Decolonization Swap Out Trial

Arm 1: Routine Care (Mupirocin/CHG) vs Arm 2: Iodophor/CHG Decolonization: Number of Participants With ICU-attributable Staphylococcus Aureus Clinical Cultures2,708 of 168,301

3,563 of 185,022

-0.3 points

-0.4 to -0.2

353,323NCT03140423

Mupirocin-Iodophor ICU Decolonization Swap Out Trial

Arm 1: Routine Care (Mupirocin/CHG) vs Arm 2: Iodophor/CHG Decolonization: Number of Participants With ICU-attributable Bloodstream Infections1,766 of 168,301

1,956 of 185,022

-0.0 points

-0.1 to 0.1

353,323NCT03140423

Mupirocin-Iodophor ICU Decolonization Swap Out Trial

Cases vs Controls: Number of Participants BMI <30 With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person1,398 of 92,915

3,188 of 249,186

0.2 points

0.1 to 0.3

342,101NCT04969653

The Incidence of Venous Thromboembolism in Atopic Dermatitis

Intervention Arm vs Usual Care Arm: Receipt of Flu Vaccine76,295 of 148,291

96,561 of 190,427

0.7 points

0.4 to 1.1

338,718NCT05027464

Developing and Testing a COVID-19 Vaccination Acceptance Intervention

Intervention Arm vs Usual Care Arm: Receipt of Any Dose COVID-19 Vaccination57,621 of 148,291

65,407 of 190,427

4.5 points

4.2 to 4.8

338,718NCT05027464

Developing and Testing a COVID-19 Vaccination Acceptance Intervention

SGLT-2i (Incl. Empa) (Matched to DPP-4i) vs DPP-4i (Matched to SGLT-2i): deaths from any cause1,371 of 163,812

2,524 of 163,812

-0.7 points

-0.8 to -0.6

327,624NCT03817463

A Study to Observe the Effectiveness of Empagliflozin, Other SGLT-2 Inhibitors, or DPP-4 Inhibitors in Patients With Type 2 Diabetes

Intervention Health Facility Participants vs Control Health Facility Participants: deaths from any cause3,917 of 159,587

3,677 of 154,684

0.1 points

-0.0 to 0.2

314,271NCT02148952

BetterBirth: A Trial of the WHO Safe Childbirth Checklist Program

Cases vs Controls: Number of Male Participants With Diagnosis of Risk of Venous Thromboembolism After the Start of Follow-up for Each Person1,070 of 61,882

3,170 of 247,459

0.4 points

0.3 to 0.6

309,341NCT04969653

The Incidence of Venous Thromboembolism in Atopic Dermatitis

Preoperative Geriatric Consult or Assessment vs No Preoperative Geriatric Consult or Assessment: 30-day Hospital Readmission643 of 7,352

20,656 of 259,147

0.8 points

0.1 to 1.5

266,499NCT02975375

The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery

Preoperative Geriatric Consult or Assessment vs No Preoperative Geriatric Consult or Assessment: deaths from any cause103 of 7,352

6,172 of 259,147

-1.0 points

-1.2 to -0.7

266,499NCT02975375

The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery

Preoperative Geriatric Consult or Assessment vs No Preoperative Geriatric Consult or Assessment: Non-independent Discharge Location5,264 of 7,352

145,822 of 259,147

15.3 points

14.3 to 16.4

266,499NCT02975375

The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery

Preoperative Geriatric Consult or Assessment vs No Preoperative Geriatric Consult or Assessment: Patient Safety Event1,129 of 7,352

50,256 of 259,147

-4.0 points

-4.9 to -3.2

266,499NCT02975375

The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery

Preoperative Geriatric Consult or Assessment vs No Preoperative Geriatric Consult or Assessment: Number of Participants With All-Cause Mortality at 90-days103 of 7,352

6,172 of 259,147

-1.0 points

-1.2 to -0.7

266,499NCT02975375

The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery

Polypharmacy vs No Polypharmacy: Institutional Discharge34,128 of 146,029

23,098 of 120,470

4.2 points

3.9 to 4.5

266,499NCT03133182

Polypharmacy and Outcomes After Elective Noncardiac Surgery

Polypharmacy vs No Polypharmacy: Hospital Readmission13,202 of 146,029

8,097 of 120,470

2.3 points

2.1 to 2.5

266,499NCT03133182

Polypharmacy and Outcomes After Elective Noncardiac Surgery

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

No key needed

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=3

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT05794191-8181103b",
        "title": "PCV13-vaccinated Participants vs Unvaccinated Participants: VE for First Event of ACP at 0-3 Years of Follow-up",
        "summary": "4543 of 72303 against 27984 of 320959; risk difference -2.4 points, 95% interval -2.6 to -2.2; NCT05794191, A Study To Learn About The Effects Of Pneumococcal Vaccine In People With HIV",
        "record": "/library/comparisons/NCT05794191-8181103b",
        "nct_id": "NCT05794191",
        "kind": "outcome",
        "participants": 393262,
        "risk_difference": {
          "value": -0.024355905493700133,
          "lower": -0.026358286689202724,
          "upper": -0.022317628326311127
        },
        "group_1": "4,543 of 72,303",
        "group_2": "27,984 of 320,959",
        "difference": "-2.4 points",
        "interval": "-2.6 to -2.2",
        "trial_title": "A Study To Learn About The Effects Of Pneumococcal Vaccine In People With HIV"
      },
      {
        "id": "NCT05214573-deaths",
        "title": "Aims 1, 2B, and 3 Groups vs Aim 2A Group: deaths from any cause",
        "summary": "22208 of 386276 against 0 of 25; risk difference 5.7 points, 95% interval -7.6 to 5.8; NCT05214573, Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk",
        "record": "/library/comparisons/NCT05214573-deaths",
        "nct_id": "NCT05214573",
        "kind": "deaths",
        "participants": 386301,
        "risk_difference": {
          "value": 0.05749257007942508,
          "lower": -0.0757016796695989,
          "upper": 0.058231067159930726
        },
        "group_1": "22,208 of 386,276",
        "group_2": "0 of 25",
        "difference": "5.7 points",
        "interval": "-7.6 to 5.8",
        "trial_title": "Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "None stated"
    }
  ],
  "next": "/api/comparisons/v1?page=4",
  "request_id": "NO8379cTWC8NACvl"
}
trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

Genes

NCBI Gene

One gene with its proteins, patents, drugs, trials, grants and papers.

Open193,990 genes2026-11-11

Trials

ClinicalTrials.gov

Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.

Open611,552 trials2026-11-12

Sequences

Patent publications

Paste a sequence and see the patents that disclose it.

For invited accounts.

Opens sequences.conductscience.org

By invitation39,249,078 sequences2026-11-05

For software

Read Trial comparisons from software.

Every answer on this page is also JSON, under /api/comparisons/v1. No key.

GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome

Ask an assistant

  • In FOURIER, how did serious adverse events compare between evolocumab and placebo?
  • Which metformin trials reported deaths, and what was the risk difference?
  • What was the number needed to treat for HELIOS-B's composite outcome?
  • Which placebo-controlled heart failure trials had the most participants?