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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last1,041 to 1,060 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Oral Semaglutide vs Placebo: Number of Participants From Randomization to First Occurrence of CKD Endpoint:Renal Death;Onset of Persistent≥50% Reduction in eGFR (CKD-EPI);Onset of Persistent eGFR(CKD-EPI)<15 mL/Min/1.73 m^2;Initiation of Chronic Renal Replacement Therapy112 of 4,825

129 of 4,825

-0.4 points

-1.0 to 0.3

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Heart Failure Requiring Hospitalisation or Urgent Heart Failure Visit146 of 4,825

167 of 4,825

-0.4 points

-1.1 to 0.3

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Non-fatal Stroke144 of 4,825

161 of 4,825

-0.4 points

-1.1 to 0.3

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of an Expanded MACE Composite Endpoint Consisting of: CV Death/Non-fatal Myocardial Infarction/ Non-fatal Stroke/Coronary Revascularisation/Unstable Angina Pectoris Requiring Hospitalisation670 of 4,825

777 of 4,825

-2.2 points

-3.6 to -0.8

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Onset of Persistent 50% or More Reduction in eGFR71 of 4,825

86 of 4,825

-0.3 points

-0.8 to 0.2

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomization to First Occurrence of a Major Adverse Cardiovascular Event (MACE), a Composite Endpoint Consisting of: Cardiovascular (CV) Death/Non-fatal Myocardial Infarction/Non-fatal Stroke579 of 4,825

668 of 4,825

-1.8 points

-3.2 to -0.5

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Chronic Limb Ischemia Hospitalisation63 of 4,825

88 of 4,825

-0.5 points

-1.0 to -0.0

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of a Composite Heart Failure Endpoint Consisting of: CV Death/Heart Failure Requiring Hospitalisation/Urgent Heart Failure Visit405 of 4,825

443 of 4,825

-0.8 points

-1.9 to 0.3

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Acute Limb Ischemia16 of 4,825

17 of 4,825

-0.0 points

-0.3 to 0.2

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomization to Time of Occurrence of CV Death301 of 4,825

320 of 4,825

-0.4 points

-1.4 to 0.6

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Unstable Angina Requiring Hospitalisation74 of 4,825

80 of 4,825

-0.1 points

-0.6 to 0.4

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of a Severe Hypoglycaemic Episode76 of 4,825

84 of 4,825

-0.2 points

-0.7 to 0.3

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Coronary Revascularisation200 of 4,825

263 of 4,825

-1.3 points

-2.2 to -0.5

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: deaths from any cause528 of 4,825

579 of 4,825

-1.1 points

-2.3 to 0.2

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to Time to Occurrence of All-cause Death528 of 4,825

577 of 4,825

-1.0 points

-2.3 to 0.3

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of a Composite Endpoint Consisting of : All-cause Death/ Non-fatal MI/ Non-fatal Stroke779 of 4,825

902 of 4,825

-2.5 points

-4.1 to -1.0

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Initiation of Chronic Renal Replacement Therapy (Dialysis or Kidney Transplantation)40 of 4,825

48 of 4,825

-0.2 points

-0.6 to 0.2

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Oral Semaglutide vs Placebo: serious adverse events2,312 of 4,825

2,427 of 4,825

-2.4 points

-4.4 to -0.4

9,650NCT03914326

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Xylitol vs Control: Number of Infants <2500 Grams385 of 4,305

679 of 5,260

-4.0 points

-5.2 to -2.7

9,565NCT02333227

Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi

Patients Receiving cCTA and FFRCT >0.80 vs Patients Receiving cCTA and FFRCT≤0.80: deaths from any cause7 of 4,737

28 of 4,737

-0.4 points

-0.7 to -0.2

9,474NCT02499679

Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care

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Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=53

{
  "data": {
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      {
        "id": "NCT03914326-500caf2e",
        "title": "Oral Semaglutide vs Placebo: Number of Participants From Randomization to First Occurrence of CKD Endpoint:Renal Death;Onset of Persistent≥50% Reduction in eGFR (CKD-EPI);Onset of Persistent eGFR(CKD-EPI)<15 mL/Min/1.73 m^2;Initiation of Chronic Renal Replacement Therapy",
        "summary": "112 of 4825 against 129 of 4825; risk difference -0.4 points, 95% interval -1.0 to 0.3; NCT03914326, A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes",
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        "trial_title": "A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes"
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      {
        "id": "NCT03914326-550f751d",
        "title": "Oral Semaglutide vs Placebo: Number of Participants From Randomisation to First Occurrence of Heart Failure Requiring Hospitalisation or Urgent Heart Failure Visit",
        "summary": "146 of 4825 against 167 of 4825; risk difference -0.4 points, 95% interval -1.1 to 0.3; NCT03914326, A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes",
        "record": "/library/comparisons/NCT03914326-550f751d",
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        "group_2": "167 of 4,825",
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        "interval": "-1.1 to 0.3",
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  "terms": [
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      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
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trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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