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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.
Most participants first33,758 with no events in either group come last1,141 to 1,160 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| LCZ696 vs Enalapril: Number of Patients - All-cause Mortality | 711 of 4,187 835 of 4,212 | -2.8 points -4.5 to -1.2 | 8,399 | NCT01035255 This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure |
| Standard Implementation Strategy Period vs Enhanced Contact Investigation Intervention Period: Number of Contacts Initiating TB Preventative Therapy | 122 of 2,829 264 of 5,560 | -0.4 points -1.3 to 0.5 | 8,389 | NCT05640648 Human-centered Design and Communities of Practice to Improve Home-based Tuberculosis Contact Investigation in Uganda |
| Standard Implementation Strategy Period vs Enhanced Contact Investigation Intervention Period: Initiation of TB Preventative Therapy | 122 of 2,829 264 of 5,560 | -0.4 points -1.3 to 0.5 | 8,389 | NCT05640648 Human-centered Design and Communities of Practice to Improve Home-based Tuberculosis Contact Investigation in Uganda |
| Simvastatin Plus Ezetimibe vs Placebo: Major Vascular Events Analyzed Amongst Patients Initially Randomized to Simvastatin Plus Ezetimibe Versus Placebo (Original Protocol-defined Primary Outcome) | 639 of 4,193 749 of 4,191 | -2.6 points -4.2 to -1.0 | 8,384 | NCT00125593 Study of Heart and Renal Protection |
| HEPLISAV vs Engerix-B: serious adverse events | 345 of 5,587 148 of 2,781 | 0.9 points -0.2 to 1.9 | 8,368 | NCT02117934 Safety and Immunogenicity Study of the Hepatitis B Vaccine, HEPLISAV™, Compared to Engerix-B® Vaccine |
| Heparin/Edoxaban Tosylate vs Heparin/Warfarin: serious adverse events | 801 of 4,118 852 of 4,122 | -1.2 points -2.9 to 0.5 | 8,240 | NCT00986154 Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study). |
| Omecamtiv Mecarbil vs Placebo: deaths from any cause | 1,078 of 4,120 1,078 of 4,112 | -0.1 points -2.0 to 1.8 | 8,232 | NCT02929329 Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction |
| Dutasteride 0.5 mg vs Placebo: serious adverse events | 748 of 4,105 837 of 4,126 | -2.1 points -3.8 to -0.4 | 8,231 | NCT00056407 "REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk |
| Omecamtiv Mecarbil vs Placebo: serious adverse events | 2,373 of 4,110 2,435 of 4,101 | -1.6 points -3.8 to 0.5 | 8,211 | NCT02929329 Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction |
| Tafamidis Treated-Overall vs Tafamidis Untreated-Overall: Number of All-Cause Deaths | 158 of 2,521 1,038 of 5,686 | -12.0 points -13.3 to -10.6 | 8,207 | NCT00628745 Transthyretin Amyloidosis Outcome Survey (THAOS) |
| AMR101 vs Placebo: Total Mortality. | 274 of 4,089 310 of 4,090 | -0.9 points -2.0 to 0.2 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: Unstable Angina Determined to be Caused by Myocardial Ischemia by Invasive / Non-invasive Testing and Requiring Emergent Hospitalization. | 108 of 4,089 157 of 4,090 | -1.2 points -2.0 to -0.4 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: Total Mortality, Nonfatal MI (Including Silent MI), or Nonfatal Stroke. | 549 of 4,089 690 of 4,090 | -3.4 points -5.0 to -1.9 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: Fatal or Nonfatal Stroke. | 98 of 4,089 134 of 4,090 | -0.9 points -1.6 to -0.2 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: Fatal or Nonfatal MI (Including Silent MI). | 250 of 4,089 355 of 4,090 | -2.6 points -3.7 to -1.4 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: CV Death. | 174 of 4,089 213 of 4,090 | -1.0 points -1.9 to -0.0 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: Composite of CV Death, Nonfatal MI (Including Silent MI), or Nonfatal Stroke. | 459 of 4,089 606 of 4,090 | -3.6 points -5.0 to -2.1 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: Composite of CV Death or Nonfatal MI (Including Silent MI). | 392 of 4,089 507 of 4,090 | -2.8 points -4.2 to -1.5 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: Non-elective Coronary Revascularization Represented as the Composite of Emergent or Urgent Classifications. | 216 of 4,089 321 of 4,090 | -2.6 points -3.6 to -1.5 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
| AMR101 vs Placebo: deaths from any cause | 274 of 4,089 310 of 4,090 | -0.9 points -2.0 to 0.2 | 8,179 | NCT01492361 A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin |
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=58
{
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"id": "NCT01035255-c1d0a2ad",
"title": "LCZ696 vs Enalapril: Number of Patients - All-cause Mortality",
"summary": "711 of 4187 against 835 of 4212; risk difference -2.8 points, 95% interval -4.5 to -1.2; NCT01035255, This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure",
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},
{
"id": "NCT05640648-51e37c9d",
"title": "Standard Implementation Strategy Period vs Enhanced Contact Investigation Intervention Period: Number of Contacts Initiating TB Preventative Therapy",
"summary": "122 of 2829 against 264 of 5560; risk difference -0.4 points, 95% interval -1.3 to 0.5; NCT05640648, Human-centered Design and Communities of Practice to Improve Home-based Tuberculosis Contact Investigation in Uganda",
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"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
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}ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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