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Diseases

One record for each disease in Open Targets 26.09 that a drug is studied for. Each joins the disease to its names and its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus, the drugs Open Targets' clinical reports study for it, each with its stage and the sources of that stage, the targets ChEMBL's mechanism records give those drugs, and the ClinicalTrials.gov trials that study it, with the comparisons and papers of those trials. Comparisons are those in CTTI's AACT copy of 23 Mar 2026.

6 sources

Search Diseases.

A disease's name or other name; its Open Targets ID, such as MONDO_0004975; or its ID in MeSH, Orphanet, the Disease Ontology or the NCI Thesaurus, such as D000544, ORPHA:238616, DOID:10652 or C2866, each Alzheimer disease's. Case and punctuation do not matter. Other words find the diseases whose names hold every one.

3,631 diseases from Open Targets.

Try searching

Diseases 3,631

Most trials with posted results first1 to 20 of 3,631

Show the results as
DiseaseDrugsApproved drugsTrialsWith posted resultsTargets
breast cancer

MONDO_0007254

1,032824,7811,278609
non-small cell lung carcinoma

MONDO_0005233

1,066594,8571,247629
type 2 diabetes mellitus

MONDO_0005148

613703,4321,174333
prostate cancer

MONDO_0008315

757332,173705537
plasma cell myeloma

MONDO_0009693

553382,088659446
rheumatoid arthritis

MONDO_0008383

454811,276572332
acute myeloid leukemia

MONDO_0018874

587192,158545470
chronic obstructive pulmonary disease

MONDO_0005002

328441,135528232
asthma

MONDO_0004979

423901,387526247
melanoma

MONDO_0005105

589221,589503429
major depressive disorder

MONDO_0002009

4721151,484498336
colorectal cancer

MONDO_0005575

741202,239435531
hepatitis C virus infection

MONDO_0005231

20617933429156
schizophrenia

MONDO_0005090

345581,137408269
myelodysplastic syndrome

MONDO_0018881

421101,221374354
HIV infectious disease

MONDO_0005109

454631,556362334
B-cell chronic lymphocytic leukemia

MONDO_0004948

345141,022335417
hypertensive disorder

MONDO_0005044

4171871,037309246
multiple sclerosis symptom measurement

EFO_0803536

27940877305352
head and neck squamous cell carcinoma

MONDO_0010150

42441,056294381

Request

GET /api/diseases/v1

A disease's name or other name; its Open Targets ID, such as MONDO_0004975; or its ID in MeSH, Orphanet, the Disease Ontology or the NCI Thesaurus, such as D000544, ORPHA:238616, DOID:10652 or C2866, each Alzheimer disease's. Case and punctuation do not matter. Other words find the diseases whose names hold every one.

Only the diseases with a trial that posted results to ClinicalTrials.gov.

No key needed

Code

Show the call in
curl "https://conductscience.org/api/diseases/v1"

Response

The first 2 of this page's 20 results. GET /api/diseases/v1

{
  "data": {
    "total": 3631,
    "results": [
      {
        "id": "MONDO_0007254",
        "title": "breast cancer",
        "name": "breast cancer",
        "summary": "1,032 drugs, 82 approved. 4,781 trials, 1,278 with posted results.",
        "record": "/library/diseases/MONDO_0007254",
        "stage": "Approval",
        "counts": {
          "drugs": 1032,
          "approved": 82,
          "targets": 609,
          "trials": 4781,
          "trials_with_results": 1278,
          "comparisons": 1000,
          "papers": 2768
        }
      },
      {
        "id": "MONDO_0005233",
        "title": "non-small cell lung carcinoma",
        "name": "non-small cell lung carcinoma",
        "summary": "1,066 drugs, 59 approved. 4,857 trials, 1,247 with posted results.",
        "record": "/library/diseases/MONDO_0005233",
        "stage": "Approval",
        "counts": {
          "drugs": 1066,
          "approved": 59,
          "targets": 629,
          "trials": 4857,
          "trials_with_results": 1247,
          "comparisons": 902,
          "papers": 2691
        }
      }
    ],
    "columns": [
      {
        "key": "name",
        "label": "Disease",
        "under": "id"
      },
      {
        "key": "counts.drugs",
        "label": "Drugs"
      },
      {
        "key": "counts.approved",
        "label": "Approved drugs"
      },
      {
        "key": "counts.trials",
        "label": "Trials"
      },
      {
        "key": "counts.trials_with_results",
        "label": "With posted results"
      },
      {
        "key": "counts.targets",
        "label": "Targets"
      }
    ],
    "order": "Most trials with posted results first",
    "kinds": {
      "all": 3631,
      "with-results": 2111
    }
  },
  "release": "diseases-2026-09-18-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ChEMBL, through Open Targets",
      "license": "CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
      "notice": null,
      "short": "CC BY-SA 3.0"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
      "short": "No license stated"
    },
    {
      "source": "NLM's MeSH",
      "license": "NLM's",
      "notice": null,
      "short": "NLM's terms"
    },
    {
      "source": "Open Targets",
      "license": "CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
      "notice": null,
      "short": "CC0 1.0"
    },
    {
      "source": "PubMed",
      "license": "NLM's terms",
      "notice": null,
      "short": "NLM's terms"
    }
  ],
  "next": "/api/diseases/v1?page=2",
  "request_id": "njyOXuRctj47Xh_B"
}

What it holds

Holds
3,631 diseases
From Open Targets. Counted 14 Nov 2026.
Release
18 Sept 2026
diseases-2026-09-18-0.1.0
Checked
Trial links passed automated checks: NLM's indexing of the trials' papers confirms 82% of the links by the disease's name that it can check, and 80% of the rest
Access
Open
No account. 60 calls a minute from one address.

The 5 lists in a disease's record, and how many diseases have each.

  • Drugs

    The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

    3,631100.0% of diseases

  • Targets

    The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

    3,11585.8% of diseases

  • Trials

    Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 31 more are not shown, since the checks do not confirm them.

    3,33491.8% of diseases

  • Comparisons in its trials

    Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

    1,54342.5% of diseases

  • Papers from its trials

    The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

    2,41366.5% of diseases

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

Genes

NCBI Gene

One gene with its proteins, patents, drugs, trials, grants and papers.

Trials

ClinicalTrials.gov

Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.

Trial comparisons

ClinicalTrials.gov

Comparisons of the groups of clinical trials, such as a risk ratio or a number needed to treat, calculated from the counts each trial posted.

Sequences

Patent publications

Paste a sequence and see the patents that disclose it.

Opens sequences.conductscience.org

Instruments

The conductscience.com catalog

One instrument from the ConductScience store with the tests, measures and species it is used for, the papers that used it, and the MeSH topics of those papers.

Drugs and targets

Open Targets

One drug with its targets, the diseases it is studied for, and the trials that name it, with their comparisons, papers and cognitive tests.

Companies

ClinicalTrials.gov

One company with the trials it leads or helps run, the drugs those trials test, the conditions they study and the organizations it runs them with.

Cell lines

Cellosaurus

One cell line with the problems Cellosaurus records for it, its relatives, the cell banks that hold it, and the papers that used it.

For software

Read Diseases from software.

Every answer on this page is also JSON, under /api/diseases/v1. No key.

GET https://conductscience.org/api/diseases/v1?q=Alzheimer%27s%20disease

Ask an assistant

  • Which drugs have been studied for Parkinson disease, and what stage does Open Targets give each?
  • Which trials of type 2 diabetes mellitus posted results, and how many people took part in each?
  • Which targets do the drugs studied for Alzheimer disease act on?
  • Which disease has the MeSH ID D000544, and what are its IDs in Orphanet and the Disease Ontology?