Genes
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One gene with its proteins, patents, drugs, trials, grants and papers.
ConductScience Library
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One record for each disease in Open Targets 26.09 that a drug is studied for. Each joins the disease to its names and its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus, the drugs Open Targets' clinical reports study for it, each with its stage and the sources of that stage, the targets ChEMBL's mechanism records give those drugs, and the ClinicalTrials.gov trials that study it, with the comparisons and papers of those trials. Comparisons are those in CTTI's AACT copy of 23 Mar 2026.
A disease's name or other name; its Open Targets ID, such as MONDO_0004975; or its ID in MeSH, Orphanet, the Disease Ontology or the NCI Thesaurus, such as D000544, ORPHA:238616, DOID:10652 or C2866, each Alzheimer disease's. Case and punctuation do not matter. Other words find the diseases whose names hold every one.
3,631 diseases from Open Targets.
Try searching
Most trials with posted results first1 to 20 of 3,631
| Disease | Drugs | Approved drugs | Trials | With posted results | Targets |
|---|---|---|---|---|---|
| breast cancer MONDO_0007254 | 1,032 | 82 | 4,781 | 1,278 | 609 |
| non-small cell lung carcinoma MONDO_0005233 | 1,066 | 59 | 4,857 | 1,247 | 629 |
| type 2 diabetes mellitus MONDO_0005148 | 613 | 70 | 3,432 | 1,174 | 333 |
| prostate cancer MONDO_0008315 | 757 | 33 | 2,173 | 705 | 537 |
| plasma cell myeloma MONDO_0009693 | 553 | 38 | 2,088 | 659 | 446 |
| rheumatoid arthritis MONDO_0008383 | 454 | 81 | 1,276 | 572 | 332 |
| acute myeloid leukemia MONDO_0018874 | 587 | 19 | 2,158 | 545 | 470 |
| chronic obstructive pulmonary disease MONDO_0005002 | 328 | 44 | 1,135 | 528 | 232 |
| asthma MONDO_0004979 | 423 | 90 | 1,387 | 526 | 247 |
| melanoma MONDO_0005105 | 589 | 22 | 1,589 | 503 | 429 |
| major depressive disorder MONDO_0002009 | 472 | 115 | 1,484 | 498 | 336 |
| colorectal cancer MONDO_0005575 | 741 | 20 | 2,239 | 435 | 531 |
| hepatitis C virus infection MONDO_0005231 | 206 | 17 | 933 | 429 | 156 |
| schizophrenia MONDO_0005090 | 345 | 58 | 1,137 | 408 | 269 |
| myelodysplastic syndrome MONDO_0018881 | 421 | 10 | 1,221 | 374 | 354 |
| HIV infectious disease MONDO_0005109 | 454 | 63 | 1,556 | 362 | 334 |
| B-cell chronic lymphocytic leukemia MONDO_0004948 | 345 | 14 | 1,022 | 335 | 417 |
| hypertensive disorder MONDO_0005044 | 417 | 187 | 1,037 | 309 | 246 |
| multiple sclerosis symptom measurement EFO_0803536 | 279 | 40 | 877 | 305 | 352 |
| head and neck squamous cell carcinoma MONDO_0010150 | 424 | 4 | 1,056 | 294 | 381 |
Code
curl "https://conductscience.org/api/diseases/v1"
Response
The first 2 of this page's 20 results. GET /api/diseases/v1
{
"data": {
"total": 3631,
"results": [
{
"id": "MONDO_0007254",
"title": "breast cancer",
"name": "breast cancer",
"summary": "1,032 drugs, 82 approved. 4,781 trials, 1,278 with posted results.",
"record": "/library/diseases/MONDO_0007254",
"stage": "Approval",
"counts": {
"drugs": 1032,
"approved": 82,
"targets": 609,
"trials": 4781,
"trials_with_results": 1278,
"comparisons": 1000,
"papers": 2768
}
},
{
"id": "MONDO_0005233",
"title": "non-small cell lung carcinoma",
"name": "non-small cell lung carcinoma",
"summary": "1,066 drugs, 59 approved. 4,857 trials, 1,247 with posted results.",
"record": "/library/diseases/MONDO_0005233",
"stage": "Approval",
"counts": {
"drugs": 1066,
"approved": 59,
"targets": 629,
"trials": 4857,
"trials_with_results": 1247,
"comparisons": 902,
"papers": 2691
}
}
],
"columns": [
{
"key": "name",
"label": "Disease",
"under": "id"
},
{
"key": "counts.drugs",
"label": "Drugs"
},
{
"key": "counts.approved",
"label": "Approved drugs"
},
{
"key": "counts.trials",
"label": "Trials"
},
{
"key": "counts.trials_with_results",
"label": "With posted results"
},
{
"key": "counts.targets",
"label": "Targets"
}
],
"order": "Most trials with posted results first",
"kinds": {
"all": 3631,
"with-results": 2111
}
},
"release": "diseases-2026-09-18-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ChEMBL, through Open Targets",
"license": "CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
"notice": null,
"short": "CC BY-SA 3.0"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
"short": "No license stated"
},
{
"source": "NLM's MeSH",
"license": "NLM's",
"notice": null,
"short": "NLM's terms"
},
{
"source": "Open Targets",
"license": "CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
"notice": null,
"short": "CC0 1.0"
},
{
"source": "PubMed",
"license": "NLM's terms",
"notice": null,
"short": "NLM's terms"
}
],
"next": "/api/diseases/v1?page=2",
"request_id": "njyOXuRctj47Xh_B"
}The 5 lists in a disease's record, and how many diseases have each.
The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
3,631100.0% of diseases
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
3,11585.8% of diseases
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 31 more are not shown, since the checks do not confirm them.
3,33491.8% of diseases
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
1,54342.5% of diseases
The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
2,41366.5% of diseases
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
ClinicalTrials.gov
Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.
ClinicalTrials.gov
Comparisons of the groups of clinical trials, such as a risk ratio or a number needed to treat, calculated from the counts each trial posted.
Patent publications
Paste a sequence and see the patents that disclose it.
Opens sequences.conductscience.org
The conductscience.com catalog
One instrument from the ConductScience store with the tests, measures and species it is used for, the papers that used it, and the MeSH topics of those papers.
Open Targets
One drug with its targets, the diseases it is studied for, and the trials that name it, with their comparisons, papers and cognitive tests.
ClinicalTrials.gov
One company with the trials it leads or helps run, the drugs those trials test, the conditions they study and the organizations it runs them with.
Cellosaurus
One cell line with the problems Cellosaurus records for it, its relatives, the cell banks that hold it, and the papers that used it.
For software
Every answer on this page is also JSON, under /api/diseases/v1. No key.
GET https://conductscience.org/api/diseases/v1?q=Alzheimer%27s%20disease
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