Disease · EFO_0004149
Comparisons in its trials25
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
1 to 20 of 25
Download this page as JSON| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Amitriptyline and Ketamine Hydrochloride Topical Analgesic cr vs Placebo Cream: serious adverse events | 4 of 227 | 4 of 231 | 458 | NCT00471445 | Trial comparisons |
| Arm A (Paclitaxel) vs Arm B (Docetaxel): deaths from any cause | 7 of 126 | 6 of 123 | 249 | NCT04001829 | Trial comparisons |
| Arm A (Paclitaxel) vs Arm B (Docetaxel): serious adverse events | 46 of 121 | 61 of 118 | 239 | NCT04001829 | Trial comparisons |
| Arm I/Group A (Duloxetine Then Placebo) vs Arm II/Group B (Placebo Then Duloxetine): serious adverse events | 1 of 108 | 3 of 107 | 215 | NCT00489411 | Trial comparisons |
| Baclofen-amitriptyline Hydrochloride-ketamine vs Placebo: serious adverse events | 1 of 101 | 1 of 102 | 203 | NCT00516503 | Trial comparisons |
| Diflunisal vs Placebo: serious adverse events | 3 of 64 | 4 of 66 | 130 | NCT00294671 | Trial comparisons |
| Arm I - Lamotrigine vs Arm II - Placebo: deaths from any cause | 0 of 61 | 0 of 63 | 124 | NCT00068445 | Trial comparisons |
| Arm I - Lamotrigine vs Arm II - Placebo: serious adverse events | 0 of 61 | 0 of 63 | 124 | NCT00068445 | Trial comparisons |
| Minocycline vs Placebo: deaths from any cause | 0 of 32 | 0 of 34 | 66 | NCT01906008 | Trial comparisons |
| Minocycline vs Placebo: serious adverse events | 0 of 32 | 0 of 34 | 66 | NCT01906008 | Trial comparisons |
| Pregabalin vs Placebo: deaths from any cause | 0 of 25 | 0 of 25 | 50 | NCT02394951 | Trial comparisons |
| Pregabalin vs Placebo: serious adverse events | 1 of 25 | 0 of 25 | 50 | NCT02394951 | Trial comparisons |
| Arm I: Glutamine vs Arm II: Placebo: Incidence of Vincristine-induced Peripheral Neuropathy | 24 of 24 | 25 of 25 | 49 | NCT00365768 | Trial comparisons |
| Arm I: Glutamine vs Arm II: Placebo: Number of Participants With Progression of Neuropathy | 11 of 24 | 19 of 25 | 49 | NCT00365768 | Trial comparisons |
| Arm I: Glutamine vs Arm II: serious adverse events | 0 of 24 | 0 of 25 | 49 | NCT00365768 | Trial comparisons |
| Gabapentin vs Placebo: deaths from any cause | 0 of 25 | 0 of 24 | 49 | NCT01506453 | Trial comparisons |
| Gabapentin vs Placebo: serious adverse events | 0 of 25 | 0 of 24 | 49 | NCT01506453 | Trial comparisons |
| Pregabalin vs Placebo: Number of Patients With Significant Pain Reduction | 5 of 24 | 3 of 24 | 48 | NCT02394951 | Trial comparisons |
| Arm I (Minocycline Hydrochloride) vs Arm II (Placebo): deaths from any cause | 0 of 22 | 0 of 23 | 45 | NCT02297412 | Trial comparisons |
| Arm I (Minocycline Hydrochloride) vs Arm II (Placebo): serious adverse events | 3 of 22 | 1 of 23 | 45 | NCT02297412 | Trial comparisons |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/EFO_0004149/comparisons