Disease · MONDO_0000256

systemic mycosis

6 sourcesdiseases-2026-09-18-0.1.0

Cite this record

ConductScience Library. systemic mycosis. Diseases, record MONDO_0000256. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0000256

On this page

Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name: systemic mycosis; Open Targets
Open Targets ID: MONDO_0000256; Open Targets
Disease Ontology: DOID:0050136; Disease Ontology
Highest stage of its drugs: Phase 3, for 2 of its 3 drugs, from ClinicalTrials.gov; Open Targets

Drugs3

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

Drug	ChEMBL ID	Type	Open Targets' stage	Stage reported by	Reports	Of them trials	Trials shown here	Source
VORICONAZOLE	CHEMBL638	Small molecule	Phase 3	ClinicalTrials.gov	5	5	5	Drugs and targets
ITRACONAZOLE	CHEMBL64391	Small molecule	Phase 3	ClinicalTrials.gov	1	1	1	Drugs and targets
FLUCONAZOLE	CHEMBL106	Small molecule	Unknown	ClinicalTrials.gov	1	1	1	Drugs and targets

Targets0

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

None in this release.

Trials7

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

Trial	Title	Phase	Participants	Results first posted	Conditions	Drugs	Linked by	Source
NCT00784368	A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection	Phase 3	55	2013-07-25	Mycoses, Candidiasis, Aspergillosis, Cryptococcosis, Blastomycosis, Histoplasmosis, Neutropenia	ITRACONAZOLE	Open Targets' reading of its record	ClinicalTrials.gov
NCT00739934	Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infection	Phase 2	40	2011-01-25	Candidiasis, Candidemia	VORICONAZOLE	Open Targets' reading of its record	ClinicalTrials.gov
NCT00556998	A Multiple-Dose Study To Evaluate The Pharmacokinetics And Safety Of Voriconazole In Immunocompromised Adolescents	Phase 2	26	2012-03-16	Pharmacokinetics	VORICONAZOLE	Open Targets' reading of its record	ClinicalTrials.gov
NCT00721578	A Study Of Indian Patients Receiving Therapy For Systemic Fungal Infections		23	2010-08-26	Systemic Fungal Infections	VORICONAZOLE	Open Targets' reading of its record	ClinicalTrials.gov
NCT01383993	Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To Less Than 15 Years Old Who Are At High Risk For Systemic Fungal Infection	Phase 2	21	2014-05-09	Aspergillosis, Aspergilloma	VORICONAZOLE	Open Targets' reading of its record	ClinicalTrials.gov
NCT00001810	An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections	Phase 3	300		Aspergillosis, Candidiasis, Fungemia, Mycoses	VORICONAZOLE	Open Targets' reading of its record	ClinicalTrials.gov
NCT00002038	Non-Comparative Study of Fluconazole in Patients With Serious Mycoses and Who Cannot Be Treated With Conventional Antifungal Therapy	Not applicable			Candidiasis, Mycoses, HIV Infections	FLUCONAZOLE	Open Targets' reading of its record	ClinicalTrials.gov

Comparisons in its trials2

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

Comparison	Group 1, with the outcome	Group 2, with the outcome	Participants	Trial	Source
Voriconazole IV vs Voriconazole Oral: serious adverse events	6 of 40	13 of 34	74	NCT00739934	Trial comparisons
Voriconazole IV vs Voriconazole Oral: serious adverse events	4 of 26	4 of 22	48	NCT00556998	Trial comparisons

Papers from its trials1

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMID	Listed as	Trials listing it
25451051	DERIVED	1

Source PubMed

Data dates

The date of each source this release read.

Open Targets: 2026-09-18; Open Targets
Drug links and their checks, from Drugs and targets: 2026-09-18; Drugs and targets
ClinicalTrials.gov, from Trials: 2026-11-12; Trials
Comparisons, from Trial comparisons: 2026-03-23; Trial comparisons
PubMed, for the checks: 2026-11-06; PubMed
MeSH, for the checks: 2026-11-10; MeSH

Sources 6

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
NLM's MeSHNLM's terms
Open TargetsCC0 1.0
PubMedNLM's terms

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
NLM's MeSHNLM's
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0000256

GET https://conductscience.org/api/diseases/v1/MONDO_0000256/drugs

API reference For AI assistants