Disease · MONDO_0002039
Trials41
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 2 more are not shown, since the checks do not confirm them.
1 to 20 of 41
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02008773 | A Double-Blind Trial of Adjunctive Valacyclovir to Improve Cognition in Early Phase Schizophrenia | Phase 2 | 170 | 2019-01-30 | Schizophrenia | VALACYCLOVIR | Its record names the disease | ClinicalTrials.gov |
| NCT02793687 | Study of Efficacy and Safety of MEXIDOL® in Ischemic Stroke Therapy | Phase 3 | 150 | 2025-02-24 | Ischemic Stroke | EMOXYPINE SUCCINATE | Open Targets' reading of its record | ClinicalTrials.gov |
| NCT00853580 | A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1 | Phase 2 | 146 | 2018-03-12 | Neurofibromatosis Type 1 | LOVASTATIN | Its record names the disease | ClinicalTrials.gov |
| NCT00453921 | Methylphenidate (Ritalin) and Memory/Attention in Traumatic Brain Injury (TBI) | Not applicable | 76 | 2018-06-07 | Brain Injury | METHYLPHENIDATE | Its record names the disease | ClinicalTrials.gov |
| NCT00487942 | Efficacy and Safety of Armodafinil as Adjunctive Therapy in Schizophrenic Adults With Cognitive Deficits | Phase 2 | 60 | 2010-12-20 | Schizophrenia | ARMODAFINIL | Its record names the disease | ClinicalTrials.gov |
| NCT00635102 | Glycine and Oral D-Cycloserine in Alcoholic Patients and Healthy Subjects | Not applicable | 57 | 2016-12-16 | Alcohol Dependence | CYCLOSERINE, GLYCINE | Its record names the disease | ClinicalTrials.gov |
| NCT03711500 | D-serine Augmentation of Neuroplasticity | Phase 1/2 | 45 | 2022-06-14 | Schizophrenia, Schizo Affective Disorder | (D)-SERINE | Its record names the disease | ClinicalTrials.gov |
| NCT04602221 | A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by Ketamine | Phase 1 | 40 | 2024-03-12 | Healthy | ICLEPERTIN, LAMOTRIGINE, OSORESNONTRINE | Its record names the disease | ClinicalTrials.gov |
| NCT04251585 | Intranasal Insulin in Parkinson's Disease | Phase 2 | 31 | 2026-02-11 | Parkinson Disease | INSULIN HUMAN | Its record names the disease | ClinicalTrials.gov |
| NCT03172026 | Maraviroc to Augment Rehabilitation Outcomes After Stroke | Phase 2/3 | 2 | 2021-08-03 | Stroke | MARAVIROC | Its record names the disease | ClinicalTrials.gov |
| NCT00528905 | Proof of Concept Study of Cognitive Improvement in Patients With Schizophrenia | Phase 2 | 400 | Schizophrenia | ISPRONICLINE | Its record names the disease | ClinicalTrials.gov | |
| NCT01095562 | Safety and Efficacy Study for Cognitive Deficits in Adult Subjects With Schizophrenia | Phase 2 | 207 | Cognitive Deficits in Schizophrenia | ABT-126 | Its record names the disease | ClinicalTrials.gov | |
| NCT00400790 | Organ Protection for Coronary Artery Bypass Graft (CABG): Propofol Versus Desflurane | Not applicable | 182 | Coronary Artery Bypass, Delirium, Dementia, Amnesia, Cognition Disorders, Morbidity | DESFLURANE, PROPOFOL | Its record names the disease | ClinicalTrials.gov | |
| NCT01678755 | A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia | Phase 2 | 157 | Schizophrenia | ABT-126 | Its record names the disease | ClinicalTrials.gov | |
| NCT04291118 | Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management | Not applicable | 150 | Chronic Sinusitis | BUDESONIDE | Open Targets' reading of its record | ClinicalTrials.gov | |
| NCT06012552 | Randomized, Double-blind, Placebo-controlled Trial of the Efficacy and Safety of Tianeptine in the Treatment of Covid Fog Symptoms in Patients After COVID-19. | Phase 2 | 140 | Nervous System Diseases | TIANEPTINE | Its record names the disease | ClinicalTrials.gov | |
| NCT03237689 | Effects of Glucocorticoids on Cognition in HIV-infected Women | Early phase 1 | 136 | Hiv | HYDROCORTISONE | Its record names the disease | ClinicalTrials.gov | |
| NCT00407277 | Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With Schizophrenia | Not applicable | 120 | Smoking, Nicotine Dependence, Schizophrenia, Schizophreniform Disorders, Schizoaffective Disorder, Psychosis | (+/-)NICOTINE, NICOTINE | Its record names the disease | ClinicalTrials.gov | |
| NCT02291783 | Phase I, Healthy Subject, Safety, Tolerability and Pharmacokinetic Study of an M1 Agonist to Treat Cognitive Impairment | Phase 1 | 108 | Alzheimer's Disease | HTL-9936 | Open Targets' reading of its record | ClinicalTrials.gov | |
| NCT05986422 | Methylprednisolone in Patients With Cognitive Deficits in Post-COVID-19 Syndrome (PCS) | Phase 2 | 96 | Post-COVID-19 Syndrome | METHYLPREDNISOLONE | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0002039/trials