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Disease · MONDO_0002050

Comparisons in its trials186

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Vortioxetine Treatment vs SSRI Treatment: Number of Participants Who Experienced of Intracranial Hemorrhage in Total Follow-up Period2 of 22,82725 of 124,950147,777NCT05932407Trial comparisons
FSC Cohort vs AC Cohort: Number of Participants With Any Chronic Obstructive Pulmonary Disease (COPD)-Related Exacerbation200 of 1,078674 of 2,9234,001NCT01337336Trial comparisons
Vortioxetine vs Placebo: serious adverse events7 of 2994 of 298597NCT00672958Trial comparisons
Venlafaxine Extended Release (ER) vs Venlafaxine Extended Release (ER) Plus Dialogues: serious adverse events10 of 26918 of 268537NCT00401726Trial comparisons
Venlafaxine Extended Release (ER) vs Venlafaxine Extended Release (ER) Plus Dialogues: Number of Patients Compliant With Therapy248 of 254232 of 239493NCT00401726Trial comparisons
Venlafaxine Extended Release (ER) vs Venlafaxine Extended Release (ER) Plus Dialogues: Number of Patients Responding Very Satisfied on Satisfaction With Depression Care Scale (SDCS)160 of 254138 of 239493NCT00401726Trial comparisons
Lumateperone 42 mg vs Placebo: deaths from any cause0 of 2410 of 243484NCT04985942Trial comparisons
Lumateperone 42 mg vs Placebo: serious adverse events1 of 2411 of 243484NCT04985942Trial comparisons
Sertraline vs Placebo: serious adverse events57 of 23463 of 235469NCT00078286Trial comparisons
Electroconvulsive Therapy (ECT) vs Ketamine Infusion: Number of Participants With Treatment Responses Based on the 16-item Quick Inventory of Depressive Symptomatology-Self-Report Scale (QIDS-SR-16)70 of 170108 of 195365NCT03113968Trial comparisons
Electroconvulsive Therapy (ECT) vs Ketamine Infusion: deaths from any cause0 of 1700 of 195365NCT03113968Trial comparisons
Electroconvulsive Therapy (ECT) vs Ketamine Infusion: serious adverse events4 of 1705 of 195365NCT03113968Trial comparisons
Electroconvulsive Therapy (ECT) vs Ketamine Infusion: Number of Participants With Treatment Responses Based on the Montgomery-Åsberg Rating Scale (MADRS)70 of 16999 of 195364NCT03113968Trial comparisons
Pregabalin vs Placebo: serious adverse events3 of 1811 of 177358NCT01432236Trial comparisons
60 mg Duloxetine vs 120 mg Duloxetine: Number of Patients With Treatment Emergent Adverse Event97 of 16789 of 171338NCT02229825Trial comparisons
60 mg Duloxetine vs 120 mg Duloxetine: Number of Patients Withdrawn Due to Adverse Events11 of 1679 of 171338NCT02229825Trial comparisons
60 mg Duloxetine vs 120 mg Duloxetine: deaths from any cause0 of 1670 of 171338NCT02229825Trial comparisons
60 mg Duloxetine vs 120 mg Duloxetine: serious adverse events6 of 1676 of 171338NCT02229825Trial comparisons
Duloxetine vs Placebo: Number of Participants With Abnormal Laboratory Values - Low Leukocyte Count11 of 2250 of 109334NCT00406848Trial comparisons
Ziprasidone vs Placebo: serious adverse events1 of 1476 of 147294NCT00483548Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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