Disease · MONDO_0002146
Trials118
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.
1 to 20 of 118
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03518034 | A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men | Phase 4 | 5,246 | 2024-03-13 | Hypogonadism, Cardiovascular Diseases | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT01143818 | ESPRIT Study in Hypogonadal Men | 1,053 | 2011-09-26 | Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov | |
| NCT01816295 | A Study in Men With Low Testosterone to Measure the Effects of Testosterone Solution on Testosterone Levels, Sex Drive and Energy | Phase 3 | 715 | 2015-10-02 | Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT04456296 | A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism | Phase 4 | 673 | 2025-03-14 | Hypogonadism, Hypogonadism, Male, Hypogonadotropic Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT00467870 | Long-term Safety Study of Intramuscular Injections of 750 mg and 1000 mg Testosterone Undecanoate in Hypogonadal Men | Phase 3 | 531 | 2017-03-07 | Hypogonadism, Primary Hypogonadism, Secondary Hypogonadism | TESTOSTERONE UNDECANOATE | Its record names the disease | ClinicalTrials.gov |
| NCT01403116 | Safety and Efficacy Trial of Oral Testosterone Undecanoate (TU) in Hypogonadal Men | Phase 3 | 325 | 2018-08-14 | Male Hypogonadism | TESTOSTERONE, TESTOSTERONE UNDECANOATE | Its record names the disease | ClinicalTrials.gov |
| NCT03198728 | Efficacy and Safety of Oral Testosterone Undecanoate in Hypogonadal Men | Phase 3 | 314 | 2023-06-28 | Hypogonadism, Male | TESTOSTERONE, TESTOSTERONE UNDECANOATE | Its record names the disease | ClinicalTrials.gov |
| NCT01446042 | Safety and Efficacy of Intranasal TBS-1 Treatment of Male Hypogonadism | Phase 3 | 306 | 2018-06-13 | Male Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT00433199 | Testosterone Treatment for Hypogonadal Men | Phase 3 | 274 | 2011-12-08 | Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT04274894 | A Study of the Effect of Topical Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism | Phase 4 | 246 | 2022-12-15 | Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT02722278 | A Study of Oral Testosterone Undecanoate (TU) in Hypogonadal Men | Phase 3 | 222 | 2018-02-23 | Hypogonadism | TESTOSTERONE UNDECANOATE | Its record names the disease | ClinicalTrials.gov |
| NCT01699178 | Open-label, Follow-up Study of Oral Testosterone Undecanoate in Hypogonadal Men | Phase 3 | 182 | 2018-10-30 | Male Hypogonadism | TESTOSTERONE, TESTOSTERONE UNDECANOATE | Its record names the disease | ClinicalTrials.gov |
| NCT01665599 | A Clinical Trial to Evaluate the Efficacy and Safety of Testosterone Gel | Phase 3 | 180 | 2017-09-20 | Adult Male Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT04320745 | A Study to Evaluate Androderm®'s Effect on Blood Pressure in Adult Hypogonodal Male Participants | Phase 4 | 168 | 2022-07-12 | Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT02149264 | A Clinical Trial to Evaluate the Efficacy and Safety of Testosterone Gel in Adult Hypogonadal Males | Phase 3 | 160 | 2017-07-28 | Adult Male Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT00702650 | A Titration Trial to Determine the Effectiveness of Testosterone MD-Lotion (Cutaneous Solution) Formulations | Phase 3 | 155 | 2011-01-05 | Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT04467697 | Ambulatory Blood Pressure Monitoring (ABPM) Extension Study of Oral Testosterone Undecanoate in Hypogonadal Men | Phase 3 | 155 | 2024-06-28 | Hypogonadism, Male | TESTOSTERONE UNDECANOATE | Its record names the disease | ClinicalTrials.gov |
| NCT02159469 | Subcutaneous Testosterone Replacement Efficacy and Safety in Adult Men Diagnosed With Hypogonadism | Phase 3 | 150 | 2018-01-09 | Hypogonadism | TESTOSTERONE ENANTHATE | Its record names the disease | ClinicalTrials.gov |
| NCT00522431 | A Study of Fortigel Testosterone Gel 2% in Males With Low Testosterone | Phase 3 | 149 | 2014-03-07 | Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
| NCT01703741 | A Multicenter Extension Trial to Evaluate the Safety of Testosterone Gel | Phase 3 | 145 | 2017-10-06 | Adult Male Hypogonadism | TESTOSTERONE | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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