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Disease · MONDO_0004822

Comparisons in its trials15

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Mannitol vs Control: Safety Profile - Sputum Microbiology81 of 23381 of 228461NCT00669331Trial comparisons
Mannitol vs Control: Safety Profile - Hematology13 of 2335 of 228461NCT00669331Trial comparisons
Mannitol vs Control: serious adverse events43 of 23351 of 228461NCT00669331Trial comparisons
CMS (Colistimethate Sodium) (SAF) vs Placebo (SAF): deaths from any cause1 of 1761 of 197373NCT03093974Trial comparisons
CMS (Colistimethate Sodium) (SAF) vs Placebo (SAF): serious adverse events31 of 17646 of 197373NCT03093974Trial comparisons
CMS (Colistimethate Sodium) (SAF) vs Placebo (SAF): deaths from any cause3 of 1522 of 135287NCT03460704Trial comparisons
CMS (Colistimethate Sodium) (SAF) vs Placebo (SAF): serious adverse events27 of 15217 of 135287NCT03460704Trial comparisons
N-acetylcysteine Group vs Control Group: Change of Number of Patients With a Positive Sputum Culture for Pseudomonas Aeruginosa8 of 815 of 80161NCT02088216Trial comparisons
N-acetylcysteine Group vs Control Group: Adverse Events (AEs) (Elevation of Liver Enzymes)3 of 810 of 80161NCT02088216Trial comparisons
N-acetylcysteine Group vs Control Group: Nature of Sputum (Number of Patients With Yellow Purulent)12 of 8131 of 80161NCT02088216Trial comparisons
N-acetylcysteine Group vs Control Group: deaths from any cause2 of 813 of 80161NCT02088216Trial comparisons
N-acetylcysteine Group vs Control Group: serious adverse events0 of 810 of 80161NCT02088216Trial comparisons
Ciprofloxacin Inhale (BAYQ3939) vs Placebo: serious adverse events4 of 606 of 64124NCT00930982Trial comparisons
QBW251 300 mg b.i.d vs Placebo: Number of Participants With Absence of Any Colony-forming Units of Potentially Pathogenic Bacteria Sputum0 of 210 of 2142NCT04396366Trial comparisons
AZD9668 vs Placebo: serious adverse events0 of 220 of 1638NCT00769119Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0004822/comparisons