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Disease · MONDO_0005249

Comparisons in its trials100

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Enhanced Treatment vs Current Practice: serious adverse events6 of 1,01715 of 2,1083,125NCT00513500Trial comparisons
Enhanced Treatment vs Current Practice: Number of Children With Fever Who Received Coartem (Artemether-lumefantrine)265 of 9632,066 of 2,0843,047NCT00513500Trial comparisons
Amikacin Inhale (BAY41-6551) vs Placebo: Number of Participants Who Received at Least One Dose of Study Drug and Reported an Adverse Event295 of 353303 of 359712NCT01799993Trial comparisons
Amikacin Inhale (BAY41-6551) vs Placebo: Number of Participants With Organ Failure69 of 35367 of 359712NCT01799993Trial comparisons
Amikacin Inhale (BAY41-6551) vs Placebo: Number of Participants Who Received at Least One Dose of Study Drug and Reported a Serious Adverse Event101 of 35397 of 359712NCT01799993Trial comparisons
Amikacin Inhale 400mg q12h vs Placebo: deaths from any cause86 of 35385 of 359712NCT01799993Trial comparisons
Amikacin Inhale 400mg q12h vs Placebo: serious adverse events101 of 35397 of 359712NCT01799993Trial comparisons
Enhanced Treatment vs Current Practice: Number of Children Who do Not Respond to Treatment for Pneumonia41 of 36241 of 203565NCT00513500Trial comparisons
Amoxicillin vs Penicillin: Treatment Failure at or Before Discharge / Day 5 Post Enrollment (Whichever Occurs First)30 of 26329 of 263526NCT01399723Trial comparisons
Amoxicillin vs Penicillin: Treatment Failure at 48 Hours (Two Full Days After Enrollment)20 of 26321 of 263526NCT01399723Trial comparisons
Amoxicillin vs Benzyl Penicillin: serious adverse events1 of 2633 of 263526NCT01399723Trial comparisons
Amikacin Inhale (BAY41-6551) vs Placebo: Number of Participants With Microbiological Response at TOC Visit150 of 255118 of 253508NCT01799993Trial comparisons
Amikacin Inhale (BAY41-6551) vs Placebo: Number of Participants With Emergence of New Respiratory Pathogens During the Aerosol Treatment Period21 of 25534 of 253508NCT01799993Trial comparisons
Amikacin Inhale (BAY41-6551) vs Placebo: Number of Participants With Microbiological Recurrence at LFU Visit12 of 25512 of 253508NCT01799993Trial comparisons
Amoxicillin vs Penicillin: Outcome (Death/Readmission) at 14 Days as Determined by Telephone or Direct Interview33 of 24442 of 250494NCT01399723Trial comparisons
Opaganib vs Placebo: Number of Subjects With Improvement to a Score of 3 or Less on the WHO Ordinal Scale for Clinical Improvement With a Scale Ranging From 8 Down to 0145 of 230138 of 233463NCT04467840Trial comparisons
Opaganib vs Placebo: Number of Participants With Low Oxygen Flow Via Nasal Cannula169 of 230167 of 233463NCT04467840Trial comparisons
Opaganib vs Placebo: Number of Participants With Treatment Emergent Adverse Events (TEAEs)155 of 230147 of 233463NCT04467840Trial comparisons
Opaganib vs Placebo: deaths from any cause44 of 23047 of 233463NCT04467840Trial comparisons
Opaganib vs Placebo: serious adverse events52 of 23052 of 233463NCT04467840Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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