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Disease · MONDO_0005477

Trials20

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT01401647Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or TachycardiaPhase 33,0242017-01-30Cardiac ArrestAMIODARONE, LIDOCAINEIts record names the diseaseClinicalTrials.gov
NCT01215253Ranolazine Implantable Cardioverter-Defibrillator TrialPhase 31,0122018-06-15Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy, Heart FailureRANOLAZINEIts record names the diseaseClinicalTrials.gov
NCT04134845A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias.Phase 2/3682025-08-15Ventricular TachycardiaDANTROLENEIts record names the diseaseClinicalTrials.gov
NCT02301390INTERVENE: Indian Trial of Endocardial Ventricular Substrate Ablation to Prevent Recurrent VT EventsNot applicable532020-01-27Ventricular TachycardiaAMIODARONEIts record names the diseaseClinicalTrials.gov
NCT01576042Pilot Study of Catheter Ablation for Ventricular Tachycardia in Patients With an Implantable Cardioverter DefibrillatorNot applicable272014-09-25Ventricular TachycardiaAMIODARONE, SOTALOLIts record names the diseaseClinicalTrials.gov
NCT03685149Pilot Randomized Trial With Flecainide in ARVC PatientsPhase 2222024-08-20Arrhythmogenic Right Ventricular CardiomyopathyFLECAINIDEIts record names the diseaseClinicalTrials.gov
NCT01097330Catheter Ablation Versus Amiodarone for Shock Prophylaxis in Defibrillator Patients With Ventricular TachycardiaPhase 3122020-01-29Defibrillators, Implantable, Tachycardia, VentricularAMIODARONEIts record names the diseaseClinicalTrials.gov
NCT02360397Ranolazine Mediated PVC Reduction in Ischemic Heart DiseasePhase 262020-01-29Ventricular Premature Complexes, Myocardial IschemiaRANOLAZINEIts record names the diseaseClinicalTrials.gov
NCT03853369Post-marketing Registration Study of Nifekalant Hydrochloride (NIF) Injection2,000Ventricular Tachycardia, Ventricular FibrillationNIFEKALANTIts record names the diseaseClinicalTrials.gov
NCT06680869Early Amiodarone in Shockable Cardiac ArrestPhase 3585Cardiac ArrestAMIODARONE HYDROCHLORIDEIts record names the diseaseClinicalTrials.gov
NCT03734562Trial to Evaluate the Efficacy and Safety of Substrate Ablation of Monomorphic Ventricular TachycardiaNot applicable180Monomorphic Ventricular TachycardiaAMIODARONE, SOTALOLIts record names the diseaseClinicalTrials.gov
NCT05524077Catheter Ablation Versus Anti-arrhythmic Drugs for Ventricular TachycardiaNot applicable162
Heart Disease Structural Disorder, Ventricular Tachycardia, Cardiomyopathy, Dilated, Sarcoidosis, Cardiomyopathy, Hypertrophic, Cardiomyopathy Ischemic, Cardiomyopathy, Familial, Arrhythmogenic Right Ventricular Cardiomyopathy 1, Arrhythmogenic Left Ventricular Cardiomyopathy
AMIODARONEIts record names the diseaseClinicalTrials.gov
NCT05511246Venous Ethanol for Ventricular TachycardiaPhase 2156Ventricular Tachycardia, Ischemic CardiomyopathyALCOHOLIts record names the diseaseClinicalTrials.gov
NCT06780215Efficacy of Varenicline Tartrate in Treating Frequent Premature Ventricular ContractionsPhase 2116Premature Ventricular Contraction (PVC)VARENICLINE, VARENICLINE TARTRATEIts record names the diseaseClinicalTrials.gov
NCT06669299Non-Invasive Programmed Stimulation (NIPS) to Guide the Subsequent VT Therapeutic StrategiesNot applicable51Ventricular Tachycardia (VT)AMIODARONE, MEXILETINE, SOTALOLIts record names the diseaseClinicalTrials.gov
NCT05619120The Effect of Late Na Current Blocker Mexiletine on Giant T-wave Electrical Alternans(STOP-TWA)Not applicable50Giant T-wave Electrical AlternansMEXILETINEIts record names the diseaseClinicalTrials.gov
NCT07566208Using Mirabegron to Control Arrhythmia-1Phase 220Ventricular Arrhythmias and Cardiac ArrestMIRABEGRONIts record names the diseaseClinicalTrials.gov
NCT00721032Anti-arrhythmic Medication v. MRI-Merge Ablation in the Treatment of Ventricular TachycardiaNot applicable0Ventricular TachycardiaAMIODARONEIts record names the diseaseClinicalTrials.gov
NCT01798277Trial Comparing Ablation With Medical Therapy in Patients With Ventricular TachycardiaPhase 30Ventricular Tachycardia, Coronary Artery DiseaseAMIODARONE, SOTALOLIts record names the diseaseClinicalTrials.gov
NCT00000518Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)Phase 3Arrhythmia, Cardiovascular Diseases, Death, Sudden, Cardiac, Heart Diseases, Tachycardia, Ventricular, Ventricular Arrhythmia, Ventricular FibrillationIMIPRAMINE, MEXILETINE, PROCAINAMIDE, QUINIDINE, SOTALOLIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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