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Disease · MONDO_0005566

Comparisons in its trials17

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
A Methadone vs B Buprenorphine: Number of Children Requiring Treatment for Neonatal Abstinence Signs (NAS)41 of 7327 of 58131NCT00271219Trial comparisons
Clonidine vs Morphine: deaths from any cause1 of 600 of 60120NCT03396588Trial comparisons
Clonidine vs Morphine: serious adverse events9 of 6015 of 60120NCT03396588Trial comparisons
Methadone vs Neonatal Morphine Solution: Number of Infants Needing a Second NAS Medication10 of 5817 of 58116NCT01958476Trial comparisons
Methadone vs Neonatal Morphine Solution: Number of Infants Needing a Dose Increase22 of 5828 of 58116NCT01958476Trial comparisons
Methadone vs Neonatal Morphine Solution: deaths from any cause0 of 580 of 58116NCT01958476Trial comparisons
Methadone vs Neonatal Morphine Solution: serious adverse events5 of 583 of 58116NCT01958476Trial comparisons
NMS/Clonidine vs NMS/Phenobarbital: serious adverse events0 of 340 of 3468NCT01175668Trial comparisons
Standard Therapy ALONE vs Standard Therapy Plus Aromatherapy: deaths from any cause0 of 190 of 1938NCT03097484Trial comparisons
Standard Therapy ALONE vs Standard Therapy Plus Aromatherapy: serious adverse events0 of 190 of 1938NCT03097484Trial comparisons
Phenobarbital vs Clonidine: Readmission Rate0 of 110 of 1425NCT03670160Trial comparisons
Phenobarbital vs Clonidine: Number of Patients Requiring Triple Therapy4 of 1110 of 1425NCT03670160Trial comparisons
Phenobarbital vs Clonidine: deaths from any cause0 of 110 of 1425NCT03670160Trial comparisons
Phenobarbital vs Clonidine: serious adverse events0 of 110 of 1425NCT03670160Trial comparisons
Treatment vs Control: deaths from any cause0 of 60 of 612NCT01360450Trial comparisons
Treatment vs Control: serious adverse events0 of 60 of 612NCT01360450Trial comparisons
Methadone Treatment Group vs Comparison Group: Readmission to Hospital0 of 40 of 59NCT03134703Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005566/comparisons