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Disease · MONDO_0006486

Comparisons in its trials15

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Tebentafusp vs Investigator's Choice: Safety: Number of Participants With Treatment Emergent Adverse Events245 of 245105 of 111356NCT03070392Trial comparisons
Tebentafusp vs Investigator's Choice: deaths from any cause84 of 24557 of 111356NCT03070392Trial comparisons
Tebentafusp vs Investigator's Choice: serious adverse events69 of 24526 of 111356NCT03070392Trial comparisons
Placebo + Dacarbazine 1000 mg/m2 vs Selumetinib 75 mg BD + Dacarbazine 1000 mg/m2: serious adverse events2 of 3220 of 97129NCT01974752Trial comparisons
Cohort 1 vs Cohort 2: Disease Control Rate18 of 358 of 1954NCT00506142Trial comparisons
Cohort 1 vs Cohort 2: serious adverse events15 of 359 of 1954NCT00506142Trial comparisons
Immunoembolization vs Plain Embolization: serious adverse events3 of 265 of 2753NCT00661622Trial comparisons
Arm A (Trametinib) vs Arm B (Trametinib, Akt Inhibitor GSK2141795): Number of Participants With Toxicity, Graded According to the National Cancer Institute CTCAE v4.0, Who Were Treated and Did Not Withdraw Consent
21 of 2121 of 2142NCT01979523Trial comparisons
Cohort A vs Cohort B: deaths from any cause23 of 2314 of 1437NCT03207347Trial comparisons
Cohort A vs Cohort B: serious adverse events8 of 237 of 1437NCT03207347Trial comparisons
Vaccine (Cycle 1, Day 1) + Dasatinib (Cycle 2, D1) vs Vaccine + Dasatinib (Cycle 1, D1): deaths from any cause8 of 95 of 615NCT01876212Trial comparisons
Vaccine (Cycle 1, Day 1) + Dasatinib (Cycle 2, D1) vs Vaccine + Dasatinib (Cycle 1, D1): serious adverse events7 of 94 of 615NCT01876212Trial comparisons
A. Stereotactic Body Radiation Therapy, Ziv-aflibercept vs B. Stereotactic Body Radiation Therapy, Ziv-aflibercept: Incidence of Adverse Events0 of 10 of 23NCT03712904Trial comparisons
A. Stereotactic Body Radiation Therapy, Ziv-aflibercept vs B. Stereotactic Body Radiation Therapy, Ziv-aflibercept: deaths from any cause0 of 11 of 23NCT03712904Trial comparisons
A. Stereotactic Body Radiation Therapy, Ziv-aflibercept vs B. Stereotactic Body Radiation Therapy, Ziv-aflibercept: serious adverse events0 of 11 of 23NCT03712904Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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