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Disease · MONDO_0009891

Comparisons in its trials12

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
PEGASYS vs Hydroxyurea: Number of Participants With Major Cardiovascular Events After Therapy1 of 821 of 86168NCT01259856Trial comparisons
PEGASYS vs Hydroxyurea: deaths from any cause0 of 821 of 86168NCT01259856Trial comparisons
PEGASYS vs Hydroxyurea: serious adverse events14 of 824 of 86168NCT01259856Trial comparisons
Ruxolitinib vs Best Available Therapy (BAT): Number of Participants Achieving a Partial Remission Based on the European Leukemia Net (ELN) and International Working Group for Myelofibrosis Research and Treatment (IWG-MRT) Criteria at Week 28
7 of 740 of 75149NCT02038036Trial comparisons
Ruxolitinib vs Best Available Therapy (BAT): Number of Participants Achieving a Complete Hematological Remission at Week 2817 of 744 of 75149NCT02038036Trial comparisons
Ruxolitinib vs Best Available Therapy (BAT): Number of Participants With Transformation Free Survival Events4 of 743 of 75149NCT02038036Trial comparisons
Ruxolitinib vs Best Available Therapy (BAT): Number of Participants Developing Thrombosis0 of 740 of 75149NCT02038036Trial comparisons
Ruxolitinib vs Best Available Therapy (BAT): Number of Participants Achieving Hematocrit (Hct) Control at Week 2846 of 7414 of 75149NCT02038036Trial comparisons
Ruxolitinib vs Best Available Therapy (BAT): Number of Participants With Overall Survival (OS) Events3 of 746 of 75149NCT02038036Trial comparisons
Ruxolitinib vs Hydroxyurea: serious adverse events5 of 544 of 56110NCT01632904Trial comparisons
GIVINOSTAT + MTD Hydroxyurea_1 vs GIVINOSTAT + MTD Hydroxyurea_2: deaths from any cause0 of 220 of 2244NCT00928707Trial comparisons
GIVINOSTAT + MTD Hydroxyurea_1 vs GIVINOSTAT + MTD Hydroxyurea_2: serious adverse events2 of 221 of 2244NCT00928707Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0009891/comparisons