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Disease · MONDO_0011719

Comparisons in its trials29

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Avapritinib vs Regorafinib: deaths from any cause89 of 23987 of 234473NCT03465722Trial comparisons
Avapritinib vs Regorafinib: serious adverse events106 of 23991 of 234473NCT03465722Trial comparisons
Ripretinib vs Sunitinib: deaths from any cause90 of 22395 of 221444NCT03673501Trial comparisons
Ripretinib vs Sunitinib: serious adverse events64 of 22361 of 221444NCT03673501Trial comparisons
Sunitinib Double-Blind Treatment vs Placebo Double-Blind Treatment: Confirmed Objective Response (CR or PR) in Subjects16 of 2430 of 118361NCT00075218Trial comparisons
Nilotinib vs Control/Cross Over to Nilotinib: Number of Responders With Confirmed Best Overall Response of Complete Response (CR) or Partial Response (PR) From Central Radiology Review During Primary Analysis (Data Cut-off: June, 2008)
1 of 1650 of 83248NCT00471328Trial comparisons
Sunitinib Double-Blind Treatment vs Placebo Double-Blind Treatment: Subjects With Pain Relief Response Using McGill Pain Questionnaire-present Pain Intensity (MPQ-PPI)46 of 15010 of 75225NCT00075218Trial comparisons
Imatinib Mesylate 400 mg vs Imatinib Mesylate 600 mg: serious adverse events46 of 7340 of 74147NCT00237185Trial comparisons
Ripretinib vs Placebo: deaths from any cause26 of 8526 of 43128NCT03353753Trial comparisons
Ripretinib vs Placebo: serious adverse events26 of 8519 of 43128NCT03353753Trial comparisons
Ripretinib vs Sunitinib: Objective Response Rate (ORR)16 of 5411 of 54108NCT04633122Trial comparisons
Ripretinib vs Sunitinib: deaths from any cause13 of 5415 of 54108NCT04633122Trial comparisons
Ripretinib vs Sunitinib: Disease Control Rate (DCR)24 of 5420 of 54108NCT04633122Trial comparisons
Ripretinib vs Sunitinib: serious adverse events9 of 5412 of 54108NCT04633122Trial comparisons
Nilotinib 800 mg vs Imatinib 800 mg: serious adverse events12 of 4810 of 4694NCT00751036Trial comparisons
Imatinib vs Placebo: serious adverse events1 of 412 of 4081NCT01151852Trial comparisons
All Participants Who Received Sunitinib vs Imatinib: serious adverse events11 of 435 of 2568NCT00372567Trial comparisons
Sunitinib (Phase 3) vs Imatinib: Number of Participants With Objective Response of Complete Response or Partial Response5 of 312 of 2657NCT00372567Trial comparisons
Cohort A vs Cohort B: Number of Participants With Physical Examination6 of 301 of 1545NCT01874665Trial comparisons
Cohort A vs Cohort B: deaths from any cause4 of 302 of 1545NCT01874665Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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