Disease · MONDO_0015486
Trials54
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.
1 to 20 of 54
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01143389 | Corneal Crosslinking in Patients With Keratoconus and Post-Refractive Ectasia | Phase 2 | 510 | 2018-05-04 | Keratoconus, Post-Refractive Ectasia | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov |
| NCT01398852 | Safety and Effectiveness Study of the VEGA UV-A System for Cross-linking in Eyes With Keratoconus and Ectasia | Phase 3 | 500 | 2013-03-04 | Keratoconus and Ectasia | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov |
| NCT03442751 | Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus | Phase 3 | 201 | 2024-01-30 | Progressive Keratoconus | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov |
| NCT00647699 | Corneal Collagen Cross-linking for Progressive Keratoconus | Phase 3 | 147 | 2016-07-07 | Progressive Keratoconus | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov |
| NCT01190306 | Safety Study of the VEGA UV-A System to Treat Keratoconus | Phase 3 | 127 | 2013-03-04 | Keratoconus | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov |
| NCT01459679 | Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery | Phase 3 | 1,721 | Keratoconus, Corneal Ectasia | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT01081561 | Collagen Cross-Linking for Keratoconus/Ectasia With and Without Intacs | Phase 2/3 | 600 | Keratoconus, Ectasia | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT04731727 | Treating Corneal Thinning Conditions With CCL Vario Riboflavin (CXL) | Early phase 1 | 600 | Keratoconus, Unstable | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT03922542 | Comparison of Standard vs. Accelerated Corneal Crosslinking | Phase 2/3 | 508 | Keratoconus, Ectasia Corneal | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT02095730 | Corneal Cross-Linking Comparing Variables | Phase 3 | 500 | Unstable Corneas | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT04094090 | Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia | Phase 2 | 500 | Keratoconus, Pellucid Marginal Corneal Degeneration, Corneal Ectasia | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT07124910 | Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases | Phase 3 | 485 | Keratoconus, Ectasia of Cornea, Pellucid Marginal Corneal Degeneration, Forme Fruste Keratoconus (FFK) | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT06100952 | Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus | Phase 3 | 398 | Keratoconus | RIBOFLAVIN, SODIUM IODIDE | Its record names the disease | ClinicalTrials.gov | |
| NCT06100939 | Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus | Phase 3 | 396 | Keratoconus | RIBOFLAVIN, SODIUM IODIDE | Its record names the disease | ClinicalTrials.gov | |
| NCT02762253 | Study of the Safety and Effectiveness of Photochemically Induced Collagen Cross-Linking in Eyes With Keratoconus. | Phase 2 | 320 | Keratoconus | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT03918408 | Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking | Phase 1 | 300 | Keratoconus, Unstable, Bacterial Keratitis, Ectasia of Cornea | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT04401865 | Safety and Effectiveness of the PXL-Platinum 330 System | Phase 1/2 | 300 | Corneal Ectasia, Keratoconus, Pellucid Marginal Corneal Degeneration | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT01325298 | UVA-Riboflavin Crosslinking Treatment of Corneal Ectasia | Phase 2 | 250 | Keratoconus, Ectasia, Corneal Ectasia | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT04667572 | Safety & Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution | Phase 1 | 249 | Keratoconus, Pellucid Marginal Corneal Degeneration, Corneal Degeneration, Corneal Ectasia | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov | |
| NCT01344187 | Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus | Phase 3 | 236 | Keratoconus | RIBOFLAVIN | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0015486/trials