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Disease · MONDO_0018975

Comparisons in its trials12

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Selumetinib 25 mg/m2 vs Placebo: deaths from any cause0 of 710 of 74145NCT04924608Trial comparisons
Selumetinib 25 mg/m2 vs Placebo: serious adverse events10 of 719 of 74145NCT04924608Trial comparisons
Lovastatin vs Placebo: deaths from any cause0 of 740 of 70144NCT00853580Trial comparisons
Lovastatin vs Placebo: serious adverse events6 of 741 of 70144NCT00853580Trial comparisons
Phase II Stratum 1 vs Phase II Stratum 2: Best Overall Response Rate (Strata 1 and 2)15 of 2712 of 2148NCT02285439Trial comparisons
Cohort A vs Cohort B: Number of Participants With Adverse Events20 of 2321 of 2245NCT02101736Trial comparisons
Cohort A vs Cohort B: deaths from any cause0 of 230 of 2245NCT02101736Trial comparisons
Cohort A vs Cohort B: serious adverse events2 of 235 of 2245NCT02101736Trial comparisons
Lapatinib vs Control: Assess the Level of ErbB2 Phosphorylation in VS.5 of 92 of 413NCT00863122Trial comparisons
N-Acetylcysteine Treatment vs Placebo: deaths from any cause0 of 50 of 510NCT04481035Trial comparisons
N-Acetylcysteine Treatment vs Placebo: serious adverse events0 of 50 of 510NCT04481035Trial comparisons
Stratum 1 vs Stratum 2: serious adverse events1 of 40 of 59NCT01365468Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0018975/comparisons