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Disease · MONDO_0021245

Trials17

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT03638622Low-cost Enabling Technology for Image-guided Photodynamic Therapy (PDT) of Oral Cancer Cancer.Phase 1/2302021-02-21Oral CancerAMINOLEVULINIC ACIDIts record names the diseaseClinicalTrials.gov
NCT00953849Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune ReactivityPhase 1/2212016-12-21Mouth NeoplasmsCALCITRIOL, CELECOXIBIts record names the diseaseClinicalTrials.gov
NCT01434394Neoadjuvant Erbitux Based Chemotherapy for Locally Advanced Oral/Oropharyngeal CancerPhase 2/3243Locally Advanced Malignant Neoplasm, Oral Cancer, Oropharyngeal Carcinoma, Effects of ChemotherapyCETUXIMABIts record names the diseaseClinicalTrials.gov
NCT00002747Surgery and Radiation Therapy With or Without Chemotherapy in Treating Patients With Mouth CancerPhase 3240Head and Neck CancerCISPLATIN, FLUOROURACILIts record names the diseaseClinicalTrials.gov
NCT01440270Neo-adjuvant Erbitux-based Chemotherapy for Locally Advanced Oral/Oropharyngeal CancerPhase 2145Locally Advanced Malignant Neoplasm, Oral Cancer, Oropharyngeal CarcinomaCETUXIMABIts record names the diseaseClinicalTrials.gov
NCT06876038Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral LesionsPhase 265Oral Cancer, Oral Cavity Cancer, Oral Leukoplakia, Oral Lichen Planus, Oral Squamous Cell CarcinomaAMINOLEVULINIC ACIDIts record names the diseaseClinicalTrials.gov
NCT05865548Addition of Aspirin to Standard of Care in Oral CancerPhase 2/360Oral CancerASPIRINIts record names the diseaseClinicalTrials.gov
NCT07082621N Acetylcystene in Treatment of Radiotherapy Induced Oral Mucositis in Oral Cancer PatientsNot applicable40Oral MucositisACETYLCYSTEINEIts record names the diseaseClinicalTrials.gov
NCT07015333Case Review of Patients With Betel Nut-induced Oral Cancer Treated With Pembrolizumab and Cetuximab31Oral Squamous Cell Carcinoma (OSCC)CETUXIMAB, PEMBROLIZUMABIts record names the diseaseClinicalTrials.gov
NCT03288051Effects of Intraoperative, Goal-directed Crystalloid vs. Colloid Fluid Resuscitation on Free FlapsNot applicable30Optimal Tissue PerfusionDOBUTAMINE, NOREPINEPHRINEOpen Targets' reading of its recordClinicalTrials.gov
NCT06627270Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral CancerPhase 230Oral Squamous Cell Carcinoma, Oral Cancer, Head and Neck Cancer, Head and Neck CarcinomaMETRONIDAZOLEIts record names the diseaseClinicalTrials.gov
NCT03934294Acupuncture Effect on Digestion in Critically Ill Post-Operative Oral and Hypo-pharyngeal Cancer PatientsNot applicable28Oral Cancer, Hypopharyngeal CancerMETOCLOPRAMIDEIts record names the diseaseClinicalTrials.gov
NCT05308732Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to RadiotherapyPhase 120Head and Neck Neoplasms, Mucositis Oral, Radiotherapy; ComplicationsCISPLATIN, FLUCONAZOLEIts record names the diseaseClinicalTrials.gov
NCT03843515Neoadjuvant Nivolumab for Oral Cancer Combined With FDG and Anti-PD-L1 PET/CT Imaging for Response PredictionPhase 117Oral Cavity Squamous Cell CarcinomaNIVOLUMABIts record names the diseaseClinicalTrials.gov
NCT02946671Study of Pre-operative Combination Therapy With Mogamulizumab and Nivolumab Against Solid Cancer PatientsPhase 116Gastric Cancer, Esophageal Cancer, Lung Cancer, Renal Cancer, Oral CancerMOGAMULIZUMAB, NIVOLUMABIts record names the diseaseClinicalTrials.gov
NCT00004094Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Advanced Cancer of the Mouth, Pharynx, or LarynxPhase 2Head and Neck CancerCARBOPLATIN, FLUOROURACIL, HYDROXYUREA, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT00004901Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Mouth CancerPhase 1/2Head and Neck CancerFLUOROURACIL, HYDROXYUREAIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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