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Disease · MONDO_0041052

Comparisons in its trials18

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
G-ER vs Placebo: serious adverse events4 of 2216 of 231452NCT00636636Trial comparisons
G-ER vs Placebo: Patient Global Impression of Change (PGIC)94 of 22077 of 230450NCT00636636Trial comparisons
G-ER vs Placebo: Clinical Global Impression of Change (CGIC)97 of 22078 of 230450NCT00636636Trial comparisons
Pregabalin CR DB vs Placebo DB: Participants With Secondary LTR Based on 5 Day Rolling Average Diary Results49 of 20887 of 205413NCT01270828Trial comparisons
Pregabalin CR DB vs Placebo DB: Number of Participants With Loss of Therapeutic Response.29 of 20863 of 205413NCT01270828Trial comparisons
Pregabalin vs Placebo: serious adverse events2 of 1110 of 109220NCT01455428Trial comparisons
XPF-002 vs Placebo: serious adverse events1 of 621 of 63125NCT01195636Trial comparisons
GEn 1200 mg vs GEn 3600 mg: Number of Participants Who Are Responders on the Patient Global Impression of Change (PGIC) at the Last Week of Each Treatment Period Using LOCF Data17 of 6328 of 61124NCT00617461Trial comparisons
XPF-002 vs Placebo: Proportion of Subjects Using Rescue Analgesic Medications During XPF-002 Treatment Compared to Placebo Treatment38 of 5740 of 57114NCT01195636Trial comparisons
XPF-002 vs Placebo: Proportion of Subjects Achieving 50% Improvement in Mean Daily Pain Score From Baseline to Week 3 on XPF-002 Treatment Compared to Placebo Treatment15 of 526 of 52104NCT01195636Trial comparisons
XPF-002 vs Placebo: Proportion of Subjects Achieving at Least a 1 Point Improvement in Mean Daily Pain Score (Measured Using the 11-point Likert NRS) From Baseline to Week 3 on XPF-002 Compared to Placebo
22 of 5219 of 52104NCT01195636Trial comparisons
XPF-002 vs Placebo: Proportion of Subjects Achieving 30% Improvement in Mean Daily Pain Score From Baseline to Week 3 on XPF-002 Treatment Compared to Placebo Treatment21 of 5212 of 52104NCT01195636Trial comparisons
GEn 1200 mg vs GEn 3600 mg: Number of Participants Who Are Responders on the Clinical Global Impression of Change (CGIC) Questionnaire at the Last Week of Each Treatment Period Using LOCF Data15 of 5318 of 48101NCT00617461Trial comparisons
Tapentadol vs Placebo: serious adverse events4 of 603 of 3191NCT01124617Trial comparisons
LX9211 vs Placebo: Number of Participants Discontinuing Treatment Due to Lack of Efficacy Defined as Increase in ADPS From Baseline of ≥30% Based on Question 5 of the ZBPI0 of 381 of 4179NCT04662281Trial comparisons
Moderate Renal Impairment vs Severe Renal Impairment: deaths from any cause0 of 300 of 535NCT02607280Trial comparisons
Moderate Renal Impairment vs Severe Renal Impairment: serious adverse events1 of 300 of 535NCT02607280Trial comparisons
Double Blind Treatment Period Civamide Nasal Spray vs Double Blind Treatment Period Placebo Nasal Spray: serious adverse events0 of 61 of 511NCT01886313Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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