Disease · MONDO_0043653
Trials23
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.
1 to 20 of 23
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02265913 | Comparative Safety and Efficacy of Two Antiviral Treatments in the Treatment of Recurrent Herpes Simplex Labialis | Phase 3 | 4,076 | 2021-01-05 | Herpes Labialis | ACYCLOVIR | Its record names the disease | ClinicalTrials.gov |
| NCT05098938 | A Study to Compare Sitavig (Acyclovir) Buccal Tablet With a Placebo in the Treatment of Herpes Labialis in Participants Whose Immune System Works Normally | Phase 3 | 2,020 | 2025-09-02 | Recurrent Herpes Labialis | ACYCLOVIR | Its record names the disease | ClinicalTrials.gov |
| NCT00769314 | Phase 3 Clinical Study for the Treatment of Cold Sore | Phase 3 | 1,727 | 2012-12-21 | Herpes Labialis | ACYCLOVIR | Its record names the disease | ClinicalTrials.gov |
| NCT01985321 | Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Treatment of Cold Sores | Phase 2 | 469 | 2015-05-28 | Recurrent Herpes Labialis | ALCOHOL, GLYCOLIC ACID | Its record names the disease | ClinicalTrials.gov |
| NCT03192306 | Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for Episodic Treatment of Cold Sores | Phase 2 | 451 | 2018-08-16 | Recurrent Herpes Labialis | ALCOHOL, ISOXAFLUTOLE | Its record names the disease | ClinicalTrials.gov |
| NCT02871492 | Trial on Efficacy and Safety of Pritelivir Ointment for Treatment of Labial Herpes | Phase 2 | 362 | 2021-07-13 | Herpes Labialis | ACYCLOVIR, PRITELIVIR | Its record names the disease | ClinicalTrials.gov |
| NCT01574612 | Open Label Safety Study of Xerese Cream in the Treatment of Recurrent Herpes Labialis in Children 6-11 Years Old | Phase 3 | 54 | 2014-05-22 | Herpes Labialis | ACYCLOVIR, HYDROCORTISONE | Its record names the disease | ClinicalTrials.gov |
| NCT01971385 | Safety and Efficacy of Squaric Acid Dibutyl Ester for the Treatment of Herpes Labialis | Phase 1 | 54 | 2017-10-02 | Herpes Labialis | SQUARIC ACID DIBUTYL ESTER | Its record names the disease | ClinicalTrials.gov |
| NCT00878072 | Safety and Pharmacokinetics of Famciclovir Single 1500 mg Dose in Adolescents With Recurrent Herpes Labialis | Phase 2/3 | 53 | 2021-06-25 | Herpes Labialis | FAMCICLOVIR | Its record names the disease | ClinicalTrials.gov |
| NCT03661541 | Immune Response and General Immune Health in Subjects Infected With Herpes Simplex Virus Type 1 (HSV-1) | Phase 1 | 36 | 2021-11-03 | HSV, Herpes Labialis | SQUARIC ACID DIBUTYL ESTER | Its record names the disease | ClinicalTrials.gov |
| NCT04893577 | EDTA Eye Drops Compared to Abreva for Herpes Simplex Virus Eruptions | Phase 2 | 10 | 2025-10-31 | Herpes Simplex Oral | DOCOSANOL, EDETIC ACID | Its record names the disease | ClinicalTrials.gov |
| NCT00453401 | Safety, Pharmacokinetics, and Efficacy Study of NB-001 to Treat Recurrent Herpes Labialis | Phase 2 | 1,000 | Herpes Labialis | NB-001 | Its record names the disease | ClinicalTrials.gov | |
| NCT01321359 | A Multicenter Study of NB-001 in the Treatment of Recurrent Herpes Labialis | Phase 3 | 907 | Recurrent Herpes Simplex Labialis | NB-001 | Its record names the disease | ClinicalTrials.gov | |
| NCT01324466 | A Multicenter Study of NB-001 in the Treatment of Recurrent Herpes Labialis (SHaRCS) | Phase 3 | 847 | Recurrent Herpes Labialis | NB-001 | Its record names the disease | ClinicalTrials.gov | |
| NCT00469300 | Iontophoretic Application of Acyclovir Gel to Treat Cold Sores | Phase 2 | 810 | Herpes Labialis | ACYCLOVIR | Its record names the disease | ClinicalTrials.gov | |
| NCT01695187 | NB-001 Treatment of Recurrent Herpes Labialis | Phase 3 | 362 | Herpes Labialis | NB-001 | Its record names the disease | ClinicalTrials.gov | |
| NCT00297011 | Valacyclovir+Temovate Gel for the Treatment of Herpes Labialis | Phase 2 | 300 | Herpes Labialis | CLOBETASOL, VALACYCLOVIR | Its record names the disease | ClinicalTrials.gov | |
| NCT00735761 | Study of ME-609 and Acyclovir for Treatment of Herpes Simplex Labialis in Immunocompromised Patients | Phase 3 | 201 | Herpes Labialis | ACYCLOVIR | Its record names the disease | ClinicalTrials.gov | |
| NCT03977792 | An Open Label Study to Evaluate the Safety and Efficacy of BOR15001L7 for the Treatment of Cold Sores in Patients With Recurrent Herpes Labialis | Phase 2 | 164 | Recurrent Herpes Labialis | DOCOSANOL | Its record names the disease | ClinicalTrials.gov | |
| NCT01257074 | Non-inferiority Comparison of Efficacy and Safety of Penciclovir 10mg/g to Acyclovir 50mg/g in the Treatment of Recurrent Herpes Labialis | Phase 3 | 76 | Herpes Labialis | PENCICLOVIR | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0043653/trials