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Disease · MONDO_0100347

Trials17

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT03223428Real-world Evidence Study EvaLuating PAtient-Reported Outcomes With XERMELO2232024-07-15Carcinoid SyndromeTELOTRISTAT ETHYLIts record names the diseaseClinicalTrials.gov
NCT01677910TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome)Phase 31352017-09-18Carcinoid SyndromeTELOTRISTATIts record names the diseaseClinicalTrials.gov
NCT00774930An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid SyndromePhase 31152016-02-09Carcinoid SyndromeLANREOTIDEIts record names the diseaseClinicalTrials.gov
NCT04810091Telotristat Ethyl for the Treatment of Carcinoid Heart Disease in Patients With Metastatic Neuroendocrine TumorPhase 3792026-02-05Locally Advanced Neuroendocrine Neoplasm, Metastatic Neuroendocrine NeoplasmTELOTRISTAT ETHYLIts record names the diseaseClinicalTrials.gov
NCT05361668Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid SyndromePhase 2362025-10-31
Carcinoid Syndrome, Carcinoid, Carcinoid Tumor, Carcinoid Tumor of Ileum, Carcinoid Tumor of Cecum, Carcinoid Syndrome Diarrhea, Carcinoid Intestine Tumor, Carcinoid Tumor of Liver, Carcinoid Tumor of Pancreas
PALTUSOTINEIts record names the diseaseClinicalTrials.gov
NCT00853047Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide TherapyPhase 2232018-12-26Carcinoid SyndromeOCTREOTIDE, TELOTRISTATIts record names the diseaseClinicalTrials.gov
NCT01104415Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid SyndromePhase 2152018-04-06Carcinoid SyndromeTELOTRISTATIts record names the diseaseClinicalTrials.gov
NCT01018953Study to Assess the Efficacy and Safety of Different Doses of BIM 23A760 in Patients With Carcinoid SyndromePhase 282015-09-07Carcinoid SyndromeONZIGOLIDEIts record names the diseaseClinicalTrials.gov
NCT01886287P:II Above-Label Octreotide-LAR With Insufficiently Controlled Carcinoid SyndromePhase 222015-01-12Neuroendocrine CarcinomaOCTREOTIDEIts record names the diseaseClinicalTrials.gov
NCT07087054Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine RegimenPhase 3141
Carcinoid Syndrome, Carcinoid, Carcinoid Tumor, Carcinoid Tumor of Ileum, Carcinoid Tumor of Cecum, Carcinoid Tumor of Liver, Carcinoid Tumor of Pancreas, Carcinoid Syndrome Diarrhea, Carcinoid Intestine Tumor
PALTUSOTINEIts record names the diseaseClinicalTrials.gov
NCT04039516Carcinoid Heart Disease and Peptide Receptor Radiotargetted TherapyPhase 220Carcinoid Heart Disease, Carcinoid Syndrome, Carcinoid TumorLUTETIUM OXODOTREOTIDE LU-177Its record names the diseaseClinicalTrials.gov
NCT00884715Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid SyndromePhase 1/210Carcinoid SyndromeOCTREOTIDEIts record names the diseaseClinicalTrials.gov
NCT00092287Comparison of Lanreotide Autogel® and Sandostatin LAR Depot in the Treatment of Clinical Symptoms Associated With Carcinoid SyndromePhase 34Malignant Carcinoid SyndromeLANREOTIDEIts record names the diseaseClinicalTrials.gov
NCT01172717Study of Panitumumab in the Treatment of Carcinoid SyndromePhase 20Carcinoid SyndromePANITUMUMABIts record names the diseaseClinicalTrials.gov
NCT04065165
Lanreotide Combined With Telotristat Ethyl or Placebo for the First-line Treatment in Patients With Advanced Well Differentiated Small Intestinal Neuroendocrine Tumours (siNET) With Highly-functioning Carcinoid Syndrome
Phase 30Small Intestinal NET, Carcinoid Heart DiseaseLANREOTIDE, TELOTRISTAT ETHYLIts record names the diseaseClinicalTrials.gov
NCT04713202
Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl
Phase 20Neuroendocrine Tumors, Carcinoid Syndrome, DiarrheaTELOTRISTAT ETHYLIts record names the diseaseClinicalTrials.gov
NCT04776876Retifanlimab (INCMGA00012) and Telotristat Ethyl for the Treatment of Advanced Neuroendocrine Tumors and Carcinoid SyndromePhase 20Advanced Neuroendocrine Neoplasm, Carcinoid SyndromeRETIFANLIMAB, TELOTRISTAT ETHYLIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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