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Disease · MONDO_0100491

Trials19

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT02672852BI 655066 / ABBV-066 (Risankizumab) in Moderate to Severe Plaque Psoriasis With Randomized Withdrawal and Re-treatmentPhase 35072019-05-28PsoriasisRISANKIZUMABIts record names the diseaseClinicalTrials.gov
NCT03782792Effisayil™ 1: A Study to Test Spesolimab (BI 655130) in Patients With a Flare-up of a Skin Disease Called Generalized Pustular PsoriasisPhase 2532022-03-09Generalized Pustular PsoriasisSPESOLIMABIts record names the diseaseClinicalTrials.gov
NCT05352893Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects With GPPPhase 3452026-03-17Generalized Pustular PsoriasisIMSIDOLIMABIts record names the diseaseClinicalTrials.gov
NCT05239039An Expanded Access Program in China to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment OptionsPhase 3392024-10-09Generalized Pustular PsoriasisSPESOLIMABIts record names the diseaseClinicalTrials.gov
NCT01794117Anakinra for Inflammatory Pustular Skin DiseasesPhase 2182021-04-30Sneddon-Wilkinson, Acrodermatitis Continua of Hallopeau, Pustular Psoriasis, Palmoplantar PustulosisANAKINRAIts record names the diseaseClinicalTrials.gov
NCT03022045A Study to Assess Efficacy and Safety of Two Different Dose Regimens of Risankizumab Administered Subcutaneously in Japanese Subjects With Generalized Pustular Psoriasis or Erythrodermic PsoriasisPhase 3182019-02-06PsoriasisRISANKIZUMABIts record names the diseaseClinicalTrials.gov
NCT01952015Study to Assess the Efficacy, Safety and Tolerability of Secukinumab in Japanese Subjects With Generalized Pustular Psoriasis (GPP)Phase 3122019-03-15PsoriasisSECUKINUMABIts record names the diseaseClinicalTrials.gov
NCT05200247An Expanded Access Trial in Japan to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment OptionsPhase 3112024-08-15Generalized Pustular PsoriasisSPESOLIMABIts record names the diseaseClinicalTrials.gov
NCT02533375Study to Investigate Efficacy and Safety of Adalimumab in Japanese Subjects With Generalized Pustular Psoriasis (GPP)Phase 3102019-01-14Generalized Pustular Psoriasis (GPP), Adalimumab, JapaneseADALIMUMABIts record names the diseaseClinicalTrials.gov
NCT03619902A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Generalized Pustular PsoriasisPhase 282022-03-29Generalized Pustular PsoriasisIMSIDOLIMABIts record names the diseaseClinicalTrials.gov
NCT02978690Spesolimab (BI 655130) Single Dose in Generalized Pustular PsoriasisPhase 172023-08-21PsoriasisSPESOLIMABIts record names the diseaseClinicalTrials.gov
NCT06952465A Study Comparing the Risk of Serious Infections and Malignancies With Deucravacitinib or Biologics in Japanese Patients With Psoriasis2,000PsoriasisDEUCRAVACITINIBIts record names the diseaseClinicalTrials.gov
NCT03886246Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous StudyPhase 2131Generalized Pustular PsoriasisSPESOLIMABIts record names the diseaseClinicalTrials.gov
NCT06391996Biologic Therapy for Generalized Pustular Psoriasis65Generalized Pustular PsoriasisSECUKINUMAB, USTEKINUMABIts record names the diseaseClinicalTrials.gov
NCT05670821PMS of Spesolimab I.V. in GPP Patients With Acute Symptoms52Generalized Pustular PsoriasisSPESOLIMABIts record names the diseaseClinicalTrials.gov
NCT05366855Study to Evaluate the Long-Term Safety and Efficacy of Imsidolimab (ANB019) in the Treatment of Subjects With GPPPhase 342Generalized Pustular PsoriasisIMSIDOLIMABIts record names the diseaseClinicalTrials.gov
NCT02343744An Efficacy and Safety Study of CNTO1959 (Guselkumab) in the Treatment of Participants With Generalized Pustular Psoriasis or Erythrodermic PsoriasisPhase 321Pustular PsoriasisGUSELKUMABIts record names the diseaseClinicalTrials.gov
NCT06323356A Study of TAK-279 in Adult Participants With Generalized Pustular Psoriasis or Erythrodermic PsoriasisPhase 318Generalized Pustular Psoriasis, Erythrodermic PsoriasisZASOCITINIBIts record names the diseaseClinicalTrials.gov
NCT06886009Spesolimab Post-marketing Surveillance in Korean Patients With Flares With Generalized Pustular Psoriasis0Generalized Pustular PsoriasisSPESOLIMABIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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