Drug · CHEMBL1237105

CARBOPROST TROMETHAMINE

7 sourcespipelines-2026-09-18-0.3.1

Cite this record

ConductScience Library. CARBOPROST TROMETHAMINE. Drugs and targets, record CHEMBL1237105. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL1237105

On this page

Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name: CARBOPROST TROMETHAMINE; ChEMBL
ChEMBL ID: CHEMBL1237105; ChEMBL
Type: Small molecule; ChEMBL
Brand names: Hemabate, Prostin/15m; ChEMBL
Other names: Carboprost trometamol, Carboprost trometanol, Carboprost tromethamine salt, U-32,921E, U-32921E; ChEMBL
Parent form: CARBOPROST, CHEMBL1237122; Drugs and targets
DrugBank: DB00429; DrugBank
InChIKey: UMMADZJLZAPZAW-XOWPVRJPSA-N; ChEMBL
Open Targets' highest stage: Approval, for 3 of its 4 diseases, from DailyMed and TTD; Open Targets

Targets1

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

Target	Protein	Mechanism	Action	Gene in Genes
PTGFR	Prostaglandin F2-alpha receptor	Prostanoid FP receptor agonist	AGONIST	https://conductscience.org/library/genes/5737

Source ChEMBL

Diseases4

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

Disease	Open Targets' stage	Stage reported by	Reports	Of them trials	Its drugs
postpartum hemorrhage	Approval	DailyMed	2	1	https://conductscience.org/library/drugs?q=EFO_0009579
uterine corpus leiomyoma	Early phase 1	ClinicalTrials.gov	1	1	https://conductscience.org/library/drugs?q=MONDO_0007886
abortion	Approval	TTD	1	0	https://conductscience.org/library/drugs?q=EFO_1001491
hemorrhage	Approval	DailyMed	1	0	https://conductscience.org/library/drugs?q=MP_0001914

Source Open Targets

Trials2

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

Trial	Title	Phase	Participants	Results first posted	Named as	Linked by	Source
NCT02861482	Early Usage of Bakri Ballon in Managing Postpartum Hemorrhage		472		hemabate	Its name	ClinicalTrials.gov
NCT05518812	Carboprost (Hemabate) for Fibroid Resection	Early phase 1	19		carboprost tromethamine	Its name	ClinicalTrials.gov

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

None in this release.

Papers from its trials1

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMID	Listed as	Trials listing it
38604533	DERIVED	1

Source PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets: 2026-09-18; Open Targets
ClinicalTrials.gov: 2026-11-05; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
Papers the trials list, from Trials: 2026-11-12; Trials
Comparisons, from Trial comparisons: 2026-03-23; Trial comparisons
Tests named in the trials, as ScienceGraph matched them: 2026-11-12; ConductCognition

Sources 7

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ChEMBL, through Open TargetsCC BY-SA 3.0
ConductCognition's list of its testsOur own data
ClinicalTrials.govNo license stated
NLM's MeSHNLM's terms
Open TargetsCC0 1.0
PubMedNLM's terms

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
ClinicalTrials.govnone stated
NLM's MeSHNLM's
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL1237105

GET https://conductscience.org/api/drugs/v1/CHEMBL1237105/targets

API reference For AI assistants