ConductScience.org, home

Drug · CHEMBL182

GANCICLOVIR

7 sourcespipelines-2026-09-18-0.3.1

Download JSON
Cite this record

ConductScience Library. GANCICLOVIR. Drugs and targets, record CHEMBL182. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL182

On this page

Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
GANCICLOVIR
ChEMBL
ChEMBL ID
CHEMBL182
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Cymevene, Cytovene, Ganzyk-rtu, Virgan, Vitrasert, Vitrasert implant, Zirgan
ChEMBL
Other names
BW 759U, BW-759U, Gancyclovir, NSC-759656, RS-21592, Valganciclovir hydrochloride impurity a
ChEMBL
Other form
GANCICLOVIR SODIUM, CHEMBL1200850
Drugs and targets
DrugBank
DB01004
DrugBank
InChIKey
IRSCQMHQWWYFCW-UHFFFAOYSA-N
ChEMBL
Open Targets' highest stage
Approval, for 4 of its 37 diseases, from ATC and DailyMed
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases37

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
cytomegalovirus retinitisApprovalDailyMed2725https://conductscience.org/library/drugs?q=MONDO_0000878
cytomegalovirus infectionPhase 3ClinicalTrials.gov1414https://conductscience.org/library/drugs?q=MONDO_0005132
AIDSPhase 3ClinicalTrials.gov44https://conductscience.org/library/drugs?q=MONDO_0012268
HIV infectious diseaseApprovalDailyMed42https://conductscience.org/library/drugs?q=MONDO_0005109
anterior uveitisPhase 2/3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0006651
malignant gliomaPhase 2ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0100342
melanomaPhase 1ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0005105
B-cell chronic lymphocytic leukemiaPhase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0004948
Global developmental delayPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0001263
acute lymphoblastic leukemiaPhase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0004967

Trials108

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT02931539
Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir
Phase 33522021-09-23ganciclovirIts nameClinicalTrials.gov
NCT00497796Maribavir Versus Oral Ganciclovir For The Prevention of Cytomegalovirus (CMV) Disease in Liver Transplant RecipientsPhase 33072015-06-04ganciclovirIts nameClinicalTrials.gov
NCT00000134Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT)Phase 32792015-09-14ganciclovirIts nameClinicalTrials.gov
NCT00000136Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT)Phase 32342015-10-22ganciclovirIts nameClinicalTrials.gov
NCT04706507Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and SepsisPhase 32052025-12-12ganciclovirIts nameClinicalTrials.gov
NCT01335932Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory FailurePhase 21602017-09-13ganciclovirIts nameClinicalTrials.gov
NCT00141037Steroid-Free Versus Steroid-Based Immunosuppression in Pediatric Renal (Kidney) TransplantationPhase 1/21302013-07-11ganciclovirIts nameClinicalTrials.gov
NCT00000143Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT)Phase 3612016-03-14ganciclovirIts nameClinicalTrials.gov
NCT00530218Ganciclovir by Infusion and by Mouth in Treating Patients With Cytomegalovirus After Donor Bone Marrow TransplantPhase 2612017-12-02ganciclovirIts nameClinicalTrials.gov
NCT03586284Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis: Treatment OutcomesPhase 2/3512026-02-10ganciclovirIts nameClinicalTrials.gov

1 to 10 of 108

See all 108 trials

Comparisons in its trials24

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Investigator-assigned Anti-CMV Treatment (IAT) vs Maribavir 400 mg: Number of Participants With All-cause Mortality by the End of the Study13 of 11727 of 235352NCT02931539Trial comparisons
Maribavir 100 mg BID vs Ganciclovir 1000 mg TID: Number of Participants Who Died Within 6 Months Post-Transplantation9 of 1476 of 156303NCT00497796Trial comparisons
Maribavir 100 mg BID vs Ganciclovir 1000 mg TID: serious adverse events71 of 14776 of 156303NCT00497796Trial comparisons
Foscarnet vs Ganciclovir: Mortality107 of 107127 of 127234NCT00000136Trial comparisons
Foscarnet vs Ganciclovir: serious adverse events60 of 10773 of 127234NCT00000136Trial comparisons
Maribavir 100 mg BID vs Ganciclovir 1000 mg TID: Number of Participants With EC-confirmed CMV Disease Within 100 Days Post-Transplantation10 of 1130 of 120233NCT00497796Trial comparisons
IV Ganciclovir vs Placebo: To Evaluate Whether Mortality and Time to Death in the 28 Days is Different Among Ganciclovir Recipients Relative to Placebo Recipients, Respectively.34 of 10613 of 99205NCT04706507Trial comparisons
IV Ganciclovir vs Placebo: To Evaluate Whether Mortality and Time to Death in the 180 Days is Different Among Ganciclovir Recipients Relative to Placebo Recipients, Respectively.45 of 10622 of 99205NCT04706507Trial comparisons
IV Ganciclovir vs Placebo: deaths from any cause45 of 10622 of 99205NCT04706507Trial comparisons
IV Ganciclovir vs Placebo: serious adverse events0 of 1060 of 99205NCT04706507Trial comparisons

Papers from its trials50

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
28829877RESULT1PubMed
25661673RESULT1PubMed
24837889RESULT1PubMed
24656016RESULT1PubMed
23665863RESULT1PubMed
23009139RESULT1PubMed
22694755RESULT1PubMed
22694733RESULT1PubMed
22510347RESULT1PubMed
21538345RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL182

GET https://conductscience.org/api/drugs/v1/CHEMBL182/diseases?page=2