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Drug · CHEMBL4

OFLOXACIN

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. OFLOXACIN. Drugs and targets, record CHEMBL4. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL4

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
OFLOXACIN
ChEMBL
ChEMBL ID
CHEMBL4
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Exocin, Floxin, Floxin otic, Ocuflox, Tarivid, Tarivid 400, Tarivid i.v., Visiren
ChEMBL
Other names
DL-8280, HOE 280, HOE-280, J01MA01, NSC-727071, NSC-758178, Ofloxacine, Ofloxacino
ChEMBL
DrugBank
DB01165
DrugBank
InChIKey
GSDSWSVVBLHKDQ-UHFFFAOYSA-N
ChEMBL
Open Targets' highest stage
Approval, for 7 of its 19 diseases, from ATC, DailyMed and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases19

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
diabetic footPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=EFO_1001459
glaucomaPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0005041
Acute otitis mediaUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0000371
FeverPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0001945
epistaxisUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=EFO_0003895
infectious otitis mediaPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0024330
myopiaUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0001384
otitis mediaPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005441
pelvic inflammatory diseasePhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0000922
reactive arthritisUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0017376

Trials29

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT02567825Efficacy of Tympanostomy Tubes for Children With Recurrent Acute Otitis Media2502021-12-10ofloxacinIts nameClinicalTrials.gov
NCT00002850Antibiotic Therapy in Preventing Early Infection in Patients With Multiple Myeloma Who Are Receiving ChemotherapyPhase 32122015-02-13ofloxacinIts nameClinicalTrials.gov
NCT02528123VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia1142024-04-23ofloxacinIts nameClinicalTrials.gov
NCT02373137Descemet Endothelial Thickness Comparison TrialPhase 4382019-07-02ofloxacinIts nameClinicalTrials.gov
NCT00042289Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy1,5782022-07-22ofloxacinIts nameClinicalTrials.gov
NCT01799356Moxifloxacin Versus Ofloxacin Plus Metronidazole in Uncomplicated Pelvic Inflammatory Disease: Multicenter Randomized Controlled TrialsPhase 41,303ofloxacinIts nameClinicalTrials.gov
NCT00578474A Phase III Study of an Otic Formulation in Acute Otitis Media With Tympanostomy TubesPhase 3911ofloxacinIts nameClinicalTrials.gov
NCT00683865Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin.Phase 3749ofloxacinIts nameClinicalTrials.gov
NCT00563394MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic UlcersPhase 3584ofloxacinIts nameClinicalTrials.gov
NCT00563433MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic UlcersPhase 3342ofloxacinIts nameClinicalTrials.gov

1 to 10 of 29

See all 29 trials

Comparisons in its trials4

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Surgical Management vs Non-Surgical Management: deaths from any cause0 of 1290 of 121250NCT02567825Trial comparisons
Surgical Management vs Non-Surgical Management: serious adverse events3 of 1297 of 121250NCT02567825Trial comparisons
UT-DSAEK vs DMEK: deaths from any cause0 of 250 of 2550NCT02373137Trial comparisons
UT-DSAEK vs DMEK: serious adverse events0 of 250 of 2550NCT02373137Trial comparisons

Papers from its trials57

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
34435591RESULT1PubMed
34076612RESULT1PubMed
33318014RESULT1PubMed
33252495RESULT1PubMed
32451908RESULT1PubMed
32015036RESULT1PubMed
31489678RESULT1PubMed
30715324RESULT1PubMed
30530925RESULT1PubMed
30358179RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL4

GET https://conductscience.org/api/drugs/v1/CHEMBL4/trials?page=2