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Drug · CHEMBL424

SALICYLIC ACID

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. SALICYLIC ACID. Drugs and targets, record CHEMBL424. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL424

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
SALICYLIC ACID
ChEMBL
ChEMBL ID
CHEMBL424
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Acnisal, Bazuka, Compound v, Compound w, Cuplex verruca, Dr. scholl's callus removers, Duofilm, Edinburgh, Erytex, Freezone, Gppe paint, Jadit, Keralyt, Metanium, Necol, Noxacorn, Occlusal, Phiso-clear, Phytex, Phytocil, Posalfilin, Pyralvex, Salactol, Salatac, Thwart, Toepedo, Verrugon, Wartex
ChEMBL
Other names
2-hydroxybenzoic acid, FEMA NO. 3985, K-557, Lamivudine impurity, salicylic acid-, Lamivudine related compound salicylic acid, NSC-180, Salicylic acid rs
ChEMBL
DrugBank
DB00936
DrugBank
InChIKey
YGSDEFSMJLZEOE-UHFFFAOYSA-N
ChEMBL
Open Targets' highest stage
Approval, for 12 of its 17 diseases, from ATC and DailyMed
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases17

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
acneApprovalDailyMed109https://conductscience.org/library/drugs?q=MONDO_0011438
psoriasisApprovalDailyMed302https://conductscience.org/library/drugs?q=MONDO_0005083
common wartApprovalDailyMed62https://conductscience.org/library/drugs?q=MONDO_0001209
plantar wartPhase 2/3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0001795
rosaceaUnknownClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0006604
actinic keratosisPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005173
frecklesEarly phase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=EFO_0003963
otomycosisUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0000262
PruritusApprovalDailyMed230https://conductscience.org/library/drugs?q=HP_0000989
seborrheic dermatitisApprovalDailyMed220https://conductscience.org/library/drugs?q=MONDO_0006608

Trials33

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 2 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT01706263U0289-402: An Open Label, 8 Week Study to Evaluate the Efficacy and Tolerability of MAXCLARITY II in Subjects With AcnePhase 4282018-01-08salicylic acidIts nameClinicalTrials.gov
NCT00616239Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic WomenPhase 4202013-12-30salicylic acidIts nameClinicalTrials.gov
NCT00848744Comparison of Two Salicylic Acid Formulations102010-07-05salicylic acidIts nameClinicalTrials.gov
NCT00944216Efficacy and Safety of Salkera Emollient Foam in the Treatment of Moderate to Severe Keratosis Pilaris, a Prospective StudyPhase 412022-02-04salicylic acidIts nameClinicalTrials.gov
NCT01059110Comparison of Five Treatments in Patients With Plantar WartsPhase 4358salicylic acidIts nameClinicalTrials.gov
NCT05497323Effectivity and Safety of Combination Cream of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad and Zinc PCAPhase 1284salicylic acidIts nameClinicalTrials.gov
NCT05862441A Study to Assess the Efficacy of Omnivirol-Salicylic Acid Combination Therapy for Cutaneous Warts With Emphasis on Persistent WartsPhase 2/3260salicylic acidIts nameClinicalTrials.gov
NCT03832647
Anti-acne Efficacy of a Dermo-cosmetic Product Associated With the Fixed Combination Adapalene 0.1%/ Benzoyl Peroxide 2.5% Treatment Versus This Treatment Associated With a Standard Moisturizer in Male and Female Subjects Presenting With Mild to Moderate Acne
Phase 4200salicylic acidIts nameClinicalTrials.gov
NCT02289768Study To Evaluate The Efficacy And Safety Of Actikerall® Solution In Patients With Grade I-II Actinic KeratosesPhase 3166salicylic acidIts nameClinicalTrials.gov
NCT07329907Combination Therapy for Warts: Candida Antigen vs. Topical KeratolyticPhase 2126salicylic acidIts nameClinicalTrials.gov

1 to 10 of 33

See all 33 trials

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

None in this release.

Papers from its trials38

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
37894698RESULT1PubMed
37806681RESULT1PubMed
36912427RESULT1PubMed
36117771RESULT1PubMed
35796684RESULT1PubMed
35600452RESULT1PubMed
35096502RESULT1PubMed
34889041RESULT1PubMed
33769633RESULT1PubMed
33690945RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL424

GET https://conductscience.org/api/drugs/v1/CHEMBL424/trials?page=2