Drug · CHEMBL49
Comparisons in its trials26
Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.
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Download this page as JSON| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Buspirone Hydrochloride vs Placebo: serious adverse events | 3 of 213 | 3 of 219 | 432 | NCT00053846 | Trial comparisons |
| Buspirone vs Placebo: serious adverse events | 0 of 88 | 0 of 87 | 175 | NCT00875836 | Trial comparisons |
| Buspirone vs Placebo: deaths from any cause | 0 of 47 | 0 of 49 | 96 | NCT03587142 | Trial comparisons |
| Buspirone vs Placebo: serious adverse events | 1 of 47 | 1 of 49 | 96 | NCT03587142 | Trial comparisons |
| Buspirone Treatment vs Buspirone Placebo: deaths from any cause | 0 of 41 | 0 of 40 | 81 | NCT01821690 | Trial comparisons |
| Buspirone Treatment vs Buspirone Placebo: serious adverse events | 0 of 41 | 1 of 40 | 81 | NCT01821690 | Trial comparisons |
| Buspirone Treatment vs Buspirone Placebo: Neuropsychiatric Inventory-Irritability Domain - Observer-rated Proportion Improved ≥ 3 Points Baseline to Day-91 | 30 of 38 | 31 of 40 | 78 | NCT01821690 | Trial comparisons |
| Buspirone Treatment vs Buspirone Placebo: Neuropsychiatric Inventory-Aggression Domain - Observer-rated Proportion Improved ≥ 3 Points Baseline to Day-91 | 28 of 38 | 27 of 40 | 78 | NCT01821690 | Trial comparisons |
| Buspirone Plus TAU vs Placebo Plus TAU: serious adverse events | 3 of 35 | 0 of 27 | 62 | NCT01641159 | Trial comparisons |
| Buspirone vs Unmedicated: deaths from any cause | 0 of 26 | 0 of 26 | 52 | NCT03538431 | Trial comparisons |
| Buspirone vs Unmedicated: serious adverse events | 0 of 26 | 0 of 26 | 52 | NCT03538431 | Trial comparisons |
| Buspirone vs Placebo: serious adverse events | 0 of 19 | 0 of 23 | 42 | NCT02132832 | Trial comparisons |
| Buspirone vs Placebo: serious adverse events | 0 of 20 | 0 of 20 | 40 | NCT01267292 | Trial comparisons |
| Buspirone vs Placebo: The Number of Participants Who Fail to Complete the 12-week Study on Study Drug. | 7 of 17 | 0 of 4 | 21 | NCT02803749 | Trial comparisons |
| Buspirone vs Placebo: deaths from any cause | 0 of 17 | 0 of 4 | 21 | NCT02803749 | Trial comparisons |
| Buspirone vs Placebo: serious adverse events | 0 of 17 | 0 of 4 | 21 | NCT02803749 | Trial comparisons |
| Buspirone vs Placebo: deaths from any cause | 0 of 10 | 0 of 10 | 20 | NCT02674412 | Trial comparisons |
| Buspirone vs Placebo: serious adverse events | 0 of 10 | 0 of 10 | 20 | NCT02674412 | Trial comparisons |
| Buspirone vs Placebo: serious adverse events | 0 of 9 | 0 of 9 | 18 | NCT01639157 | Trial comparisons |
| Buspirone vs Placebo: deaths from any cause | 0 of 8 | 0 of 8 | 16 | NCT01843205 | Trial comparisons |
pipelines-2026-09-18-0.3.1
Sources 7
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ConductCognition's list of its testsOur own data
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/drugs/v1/CHEMBL49/comparisons