Drug · CHEMBL504
DIMETHYL SULFOXIDE
7 sourcespipelines-2026-09-18-0.3.1
Cite this record
ConductScience Library. DIMETHYL SULFOXIDE. Drugs and targets, record CHEMBL504. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL504
On this page
Drug
Names and IDs as ChEMBL gives them, through Open Targets.
- Open Targets' highest stage
- Approval, for 6 of its 11 diseases, from ATC, DailyMed, PMDA and TTD
- Open Targets
Targets0
The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.
None in this release.
Diseases11
The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Disease | Open Targets' stage | Stage reported by | Reports | Of them trials | Its drugs |
|---|---|---|---|---|---|
| chronic interstitial cystitis | Approval | PMDA | 5 | 4 | https://conductscience.org/library/drugs?q=EFO_1000869 |
| Urinary incontinence | Phase 3 | ClinicalTrials.gov | 2 | 2 | https://conductscience.org/library/drugs?q=HP_0000020 |
| overactive bladder | Phase 3 | ClinicalTrials.gov | 2 | 2 | https://conductscience.org/library/drugs?q=MONDO_0006624 |
| Thrombocytopenia | Phase 1 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=HP_0001873 |
| hemorrhage | Phase 1 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MP_0001914 |
| melanoma | Phase 1 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0005105 |
| Arthralgia | Approval | ATC | 1 | 0 | https://conductscience.org/library/drugs?q=HP_0002829 |
| Myalgia | Approval | ATC | 1 | 0 | https://conductscience.org/library/drugs?q=HP_0003326 |
| cystitis | Approval | DailyMed | 1 | 0 | https://conductscience.org/library/drugs?q=MONDO_0006032 |
| infection | Approval | DailyMed | 1 | 0 | https://conductscience.org/library/drugs?q=EFO_0000544 |
1 to 10 of 11Source Open Targets
See all 11 diseasesTrials14
Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 1 more rests on that reading alone and is shown because the trial's posted result groups or NLM's indexing of its papers name the drug. 2 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.
| Trial | Title | Phase | Participants | Results first posted | Named as | Linked by | Source |
|---|---|---|---|---|---|---|---|
| NCT02078284 | Phase 1 Safety Study of Dimethyl Sulfoxide Cryopreserved Platelets | Phase 1 | 28 | 2021-05-20 | dimethyl sulfoxide cryopreserved platelets | Open Targets' reading, confirmed by the trial's result groups and NLM's indexing of its papers | ClinicalTrials.gov |
| NCT00583219 | Botulin-A Toxin Instillations and Overactive Bladder | Phase 1/2 | 25 | 2014-04-21 | dimethyl sulfoxide | Its name | ClinicalTrials.gov |
| NCT00667095 | Over Active Bladder Instillation Study - Botox | Phase 3 | 25 | 2014-07-11 | dimethyl sulfoxide | Its name | ClinicalTrials.gov |
| NCT02206477 | DMSO for Prevention of Capsular Contraction in Alloplastic Breast Reconstruction | Phase 2/3 | 110 | dimethyl sulfoxide | Its name | ClinicalTrials.gov | |
| NCT05223244 | Bladder Capacity as Objective Measure of Intravesical Treatment of Newly Diagnosed IC | Phase 4 | 83 | dimethyl sulfoxide | Its name | ClinicalTrials.gov | |
| NCT05187494 | Enhancing the Efficiency of EMLA Cream in Palatal Anesthesia for Children | 75 | dimethyl sulfoxide | Its name | ClinicalTrials.gov | ||
| NCT01069263 | Comparative Study Between Hyperbaric Therapy and Intravesical Dimethyl Sulfoxide Instillation for Interstitial Cystitis | 60 | dimethyl sulfoxide | Its name | ClinicalTrials.gov | ||
| NCT03716583 | Melatonin Cream Against Acute Radiation Dermatitis in Patients With Early Breast Cancer | Phase 2 | 48 | dimethyl sulfoxide | Its name | ClinicalTrials.gov | |
| NCT07196618 | Bond Strength Evaluation | 30 | dimethyl sulfoxide | Its name | ClinicalTrials.gov | ||
| NCT02337192 | Antimicrobial Photodynamic Therapy Applied in Orthodontic. Orthodontic Patients. | Phase 1 | 24 | dmso | Its name | ClinicalTrials.gov |
1 to 10 of 14
See all 14 trialsComparisons in its trials1
Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.
| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial |
|---|---|---|---|---|
| Botox and DMSO Instillation vs DMSO Instillation: serious adverse events | 0 of 11 | 2 of 10 | 21 | NCT00667095 |
Source Trial comparisons
Papers from its trials3
The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Tests in its trials0
The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.
None in this release.
Data dates
The date of each source this release read.
Sources 7
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ConductCognition's list of its testsOur own data
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this drug from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/drugs/v1/CHEMBL504
GET https://conductscience.org/api/drugs/v1/CHEMBL504/targets