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Drug · CHEMBL790

CHLORHEXIDINE

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. CHLORHEXIDINE. Drugs and targets, record CHEMBL790. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL790

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
CHLORHEXIDINE
ChEMBL
ChEMBL ID
CHEMBL790
ChEMBL
Type
Small molecule
ChEMBL
Other names
Avagard, Chlorhexadine, Clorhexidina, Dentisept, Merfen-incolore
ChEMBL
Other form
CHLORHEXIDINE DIACETATE, CHEMBL486819
Drugs and targets
Other form
CHLORHEXIDINE GLUCONATE, CHEMBL4297088
Drugs and targets
DrugBank
DB00878
DrugBank
InChIKey
GHXZTYHSJHQHIJ-UHFFFAOYSA-N
ChEMBL
Open Targets' highest stage
Approval, for 3 of its 20 diseases, from ATC and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases20

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
gingivitisPhase 3ClinicalTrials.gov3232https://conductscience.org/library/drugs?q=MONDO_0002508
periodontitisPhase 3ClinicalTrials.gov1717https://conductscience.org/library/drugs?q=MONDO_0005076
dental cariesPhase 3ClinicalTrials.gov99https://conductscience.org/library/drugs?q=MONDO_0005276
periodontal disorderPhase 3ClinicalTrials.gov88https://conductscience.org/library/drugs?q=MONDO_0002635
chronic periodontitisPhase 2ClinicalTrials.gov44https://conductscience.org/library/drugs?q=MONDO_0005593
bacterial infectious diseaseApprovalTTD32https://conductscience.org/library/drugs?q=MONDO_0005113
infectionApprovalATC32https://conductscience.org/library/drugs?q=EFO_0000544
Gingival bleedingUnknownClinicalTrials.gov22https://conductscience.org/library/drugs?q=HP_0000225
Peri-ImplantitisEarly phase 1ClinicalTrials.gov22https://conductscience.org/library/drugs?q=EFO_1001390
methicillin-resistant staphylococcus aureus infectious diseasePhase 2ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0100073

Trials245

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 1 more rests on that reading alone and is shown because the trial's posted result groups or NLM's indexing of its papers name the drug. 1 more that Open Targets linked to it is not shown, since the release's checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT00980980Cluster Randomized Trial of Hospitals to Assess Impact of Targeted Versus Universal Strategies to Reduce Methicillin-resistant Staphylococcus Aureus (MRSA) in Intensive Care Units (ICUs)74,2562014-07-30chlorhexidineIts nameClinicalTrials.gov
NCT03523962Pre-operative Alcohol Skin Solutions in Fractured ExtremitiesPhase 48,4852024-10-04chlorhexidineIts nameClinicalTrials.gov
NCT00719329Impact of Chlorhexidine Cleansing on Bacteria Colonizing the Umbilical Cord of Infants in Bangladesh1,9312012-04-20chlorhexidineIts nameClinicalTrials.gov
NCT01870583Comparison of Surgical Skin Preps During Cesarean Deliveries1,4042017-06-19chlorhexidineIts nameClinicalTrials.gov
NCT01472549The Skin Prep Study1,1472018-08-08chlorhexidineIts nameClinicalTrials.gov
NCT00290290Efficacy Study of Antiseptic Preoperative Scrubs in Prevention of Postoperative InfectionsPhase 38492014-08-11chlorhexidineIts nameClinicalTrials.gov
NCT02572791Staph Household Intervention for Eradication (SHINE)Phase 48352026-02-24chlorhexidineIts nameClinicalTrials.gov
NCT04954313Baseline Oral Health Study: UnCoVer the Connections to General HealthPhase 47862026-02-12chlorhexidineIts nameClinicalTrials.gov
NCT02831816Clinical Evaluation of Patient Preoperative PrepPhase 36402021-07-16chlorhexidineIts nameClinicalTrials.gov
NCT02831998In-vivo Efficacy of Patient Preoperative PrepPhase 34402021-07-19chlorhexidineIts nameClinicalTrials.gov

1 to 10 of 245

See all 245 trials

Comparisons in its trials44

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Arm 2: Decolonization vs Arm 1: Usual Care: deaths from any cause0 of 183,0130 of 156,889339,902NCT02063867Trial comparisons
Arm 2: Decolonization vs Arm 1: Usual Care: serious adverse events0 of 183,0130 of 156,889339,902NCT02063867Trial comparisons
Chlorhexidine-alcohol vs Iodine-alcohol: Number of Participants With Skin Irritation0 of 5723 of 5751,147NCT01472549Trial comparisons
Chlorhexidine-alcohol vs Iodine-alcohol: Number of Participants With Allergic Reaction2 of 5721 of 5751,147NCT01472549Trial comparisons
Chlorhexidine-alcohol vs Iodine-alcohol: Number of Participants With Surgical Site Infection23 of 57242 of 5751,147NCT01472549Trial comparisons
Chlorhexidine-alcohol vs Iodine-alcohol: deaths from any cause0 of 5720 of 5751,147NCT01472549Trial comparisons
Chlorhexidine-alcohol vs Iodine-alcohol: Number of Participants With Re-admissions or Office Visits for Wound-related Problems19 of 57225 of 5751,147NCT01472549Trial comparisons
Chlorhexidine-alcohol vs Iodine-alcohol: Number of Participants With Endometritis8 of 57211 of 5751,147NCT01472549Trial comparisons
Chlorhexidine-alcohol vs Iodine-alcohol: serious adverse events0 of 5720 of 5751,147NCT01472549Trial comparisons
Povidone-Iodine vs Chlorhexidine-Alcohol: serious adverse events3 of 4404 of 409849NCT00290290Trial comparisons

Papers from its trials185

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
39275820RESULT1PubMed
38594113RESULT1PubMed
37285925RESULT1PubMed
37272680RESULT1PubMed
36875531RESULT1PubMed
35968157RESULT1PubMed
35965392RESULT1PubMed
35287956RESULT1PubMed
34743107RESULT1PubMed
34134691RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL790

GET https://conductscience.org/api/drugs/v1/CHEMBL790/trials?page=2