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Drug · CHEMBL986

RETINOL

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. RETINOL. Drugs and targets, record CHEMBL986. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL986

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
RETINOL
ChEMBL
ChEMBL ID
CHEMBL986
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Arovit, Nepalm, Ro-a-vit, Vitamin a, Vitamin a 1
ChEMBL
Other names
NSC-122759, Retinol (vit a), Vitamin a
ChEMBL
Other form
GILDEURETINOL, CHEMBL5314606
Drugs and targets
DrugBank
DB00162
DrugBank
InChIKey
FPIPGXGPPPQFEQ-OVSJKPMPSA-N
ChEMBL
Open Targets' highest stage
Approval, for 4 of its 27 diseases, from ATC and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases27

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
SepsisPhase 3ClinicalTrials.gov33https://conductscience.org/library/drugs?q=HP_0100806
bronchopulmonary dysplasiaPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0019091
acneApprovalATC21https://conductscience.org/library/drugs?q=MONDO_0011438
Patent ductus arteriosusPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0001643
anemiaPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0002280
cervical cancerPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0002974
colorectal cancerPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005575
keratoconusPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0015486
malignant epithelial tumor of ovaryPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0018364
newborn respiratory distress syndromePhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0700081

Trials65

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 1 more that Open Targets linked to it is not shown, since the release's checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT02906566Retinol on Human Skin Aging in East Asian DescentPhase 41102019-04-16retinolIts nameClinicalTrials.gov
NCT02649192Influenza Virus Vaccine Plus Vitamin A and D Supplements for Prevention of Respiratory Virus Infections in ChildrenPhase 2872019-09-25vitamin AIts nameClinicalTrials.gov
NCT03112863Comparison of the Cosmetic Effects of Bakuchiol and RetinolEarly phase 1442021-11-02retinolIts nameClinicalTrials.gov
NCT01283464Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and WrinklesPhase 2242013-08-20retinolIts nameClinicalTrials.gov
NCT03870529High Dose Vitamin A Compound in Treating Participants With Resectable Non-Small Cell Lung CancerEarly phase 1202024-01-09vitamin AIts nameClinicalTrials.gov
NCT00222547Deworming and Enhanced Vitamin A Every 6 Month in Rural Indian Children Aged 1-6Phase 4720,000vitamin AIts nameClinicalTrials.gov
NCT01138449Efficacy of Newborn Vitamin A Supplementation Versus Placebo in Improving Child Survival (NeoVitA Trial)44,984vitamin AIts nameClinicalTrials.gov
NCT00198718Single-dose Postpartum Vitamin A Supplementation of Mothers and NeonatesPhase 228,220vitamin AIts nameClinicalTrials.gov
NCT00114868Vitamin A Supplementation in Newborns StudyPhase 314,035vitamin AIts nameClinicalTrials.gov
NCT00168636Different Doses of Vitamin A Supplementation and Male and Female Morbidity and MortalityPhase 411,000vitamin aIts nameClinicalTrials.gov

1 to 10 of 65

See all 65 trials

Comparisons in its trials5

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Older Group Ages 55-75 vs Young Group Ages 18-25: deaths from any cause0 of 240 of 1034NCT02906566Trial comparisons
Older Group Ages 55-75 vs Young Group Ages 18-25: serious adverse events0 of 240 of 1034NCT02906566Trial comparisons
Retinol vs Tretinoin: serious adverse events1 of 122 of 1224NCT01283464Trial comparisons
Vitamin A Compound vs Therapeutic Conventional Surgery: deaths from any cause0 of 110 of 920NCT03870529Trial comparisons
Vitamin A Compound vs Therapeutic Conventional Surgery: serious adverse events0 of 110 of 920NCT03870529Trial comparisons

Papers from its trials77

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
25499546RESULT1PubMed
24918554RESULT1PubMed
24289974RESULT1PubMed
22535764RESULT1PubMed
21164424RESULT1PubMed
19759098RESULT1PubMed
19437315RESULT1PubMed
18356336RESULT1PubMed
17951487RESULT1PubMed
16185228RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL986

GET https://conductscience.org/api/drugs/v1/CHEMBL986/diseases?page=2